Obesity and adverse breast cancer risk and outcome: Mechanistic insights and strategies for intervention M Picon‐Ruiz, C Morata‐Tarifa, JJ Valle‐Goffin, ER Friedman, ... CA: a cancer journal for clinicians 67 (5), 378-397, 2017 | 984 | 2017 |
VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2 D Zhao, C Pan, J Sun, C Gilbert, K Drews-Elger, DJ Azzam, M Picon-Ruiz, ... Oncogene 34 (24), 3107-3119, 2015 | 288 | 2015 |
Interactions between adipocytes and breast cancer cells stimulate cytokine production and drive Src/Sox2/miR-302b–mediated malignant progression M Picon-Ruiz, C Pan, K Drews-Elger, K Jang, AH Besser, D Zhao, ... Cancer research 76 (2), 491-504, 2016 | 189 | 2016 |
Low adherent cancer cell subpopulations are enriched in tumorigenic and metastatic epithelial-to-mesenchymal transition-induced cancer stem-like cells C Morata-Tarifa, G Jiménez, MA García, JM Entrena, C Griñán-Lisón, ... Scientific reports 6 (1), 18772, 2016 | 125 | 2016 |
VEGFA links self-renewal and metastasis by inducing Sox2 to repress miR-452, driving Slug M Kim, K Jang, P Miller, M Picon-Ruiz, TM Yeasky, D El-Ashry, ... Oncogene 36 (36), 5199-5211, 2017 | 110 | 2017 |
Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ‐secretase inhibitor drug responses DJ Azzam, D Zhao, J Sun, AJ Minn, P Ranganathan, K Drews‐Elger, ... EMBO molecular medicine 5 (10), 1502-1522, 2013 | 85 | 2013 |
Chondrocytes extract from patients with osteoarthritis induces chondrogenesis in infrapatellar fat pad-derived stem cells E López-Ruiz, M Perán, J Cobo-Molinos, G Jiménez, M Picón, ... Osteoarthritis and Cartilage 21 (1), 246-258, 2013 | 84 | 2013 |
The major pre-and postmenopausal estrogens play opposing roles in obesity-driven mammary inflammation and breast cancer development R Qureshi, M Picon-Ruiz, I Aurrekoetxea-Rodriguez, VN de Paiva, ... Cell Metabolism 31 (6), 1154-1172. e9, 2020 | 82 | 2020 |
Vitamin D and androgen receptor-targeted therapy for triple-negative breast cancer A Thakkar, B Wang, M Picon-Ruiz, P Buchwald, TA Ince Breast cancer research and treatment 157, 77-90, 2016 | 76 | 2016 |
Purification and long-term expansion of multipotent endothelial-like cells with potential cardiovascular regeneration JA Marchal, M Picón, M Perán, C Bueno, M Jiménez-Navarro, E Carrillo, ... Stem Cells and Development 21 (4), 562-574, 2012 | 45 | 2012 |
HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib A Ramirez, H Boulaiz Tassi, C Morata Tarifa, M Perán Quesada, ... Impact Journals, 2014 | 32 | 2014 |
Validation of suitable normalizers for miR expression patterns analysis covering tumour heterogeneity C Morata-Tarifa, M Picon-Ruiz, C Griñan-Lison, H Boulaiz, M Perán, ... Scientific Reports 7 (1), 39782, 2017 | 24 | 2017 |
Promotion of human adipose‐derived stem cell proliferation mediated by exogenous nucleosides F Rodríguez‐Serrano, P Alvarez, O Caba, M Picon, JA Marchal, M Perán, ... Cell biology international 34 (9), 917-924, 2010 | 23 | 2010 |
Dual role of fibroblasts educated by tumour in cancer behavior and therapeutic perspectives B Toledo, M Picon-Ruiz, JA Marchal, M Perán International journal of molecular sciences 23 (24), 15576, 2022 | 20 | 2022 |
Apoptosis as a therapeutic target in cancer and cancer stem cells: novel strategies and futures perspectives MA García, E Carrasco, A Ramírez, G Jiménez, E López-Ruiz, M Perán, ... Apoptosis and medicine, 2012 | 19 | 2012 |
Estrone, the major postmenopausal estrogen, binds ERa to induce SNAI2, epithelial-to-mesenchymal transition, and ER+ breast cancer metastasis R Qureshi, M Picon-Ruiz, M Sho, D Van Booven, VN de Paiva, ... Cell reports 41 (7), 2022 | 15 | 2022 |
Estradiol and estrone have different biological functions to induce NF-κB-driven inflammation, EMT and stemness in ER+ cancer cells AB Diaz-Ruano, N Martinez-Alarcon, M Perán, K Benabdellah, ... International Journal of Molecular Sciences 24 (2), 1221, 2023 | 11 | 2023 |
Cardiomyogenic differentiation potential of human endothelial progenitor cells isolated from patients with myocardial infarction E López-Ruiz, M Perán, M Picón-Ruiz, MA García, E Carrillo, ... Cytotherapy 16 (9), 1229-1237, 2014 | 11 | 2014 |
Obtaining human breast adipose cells for breast cancer cell co-culture studies M Picon-Ruiz, JA Marchal, JM Slingerland STAR protocols 1 (3), 100197, 2020 | 9 | 2020 |
Mammary adipocytes mediate cytokine production and malignant progression of ER-positive breast cancer through NF-kB activation MP Ruiz, CM Tarifa, R Qureshi, H Yoon, M Shin, H Kurani, JM Slingerland Cancer Research 78 (13_Supplement), 4501-4501, 2018 | 3 | 2018 |