| A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear LD Landegger, B Pan, C Askew, SJ Wassmer, SD Gluck, A Galvin, ... Nature biotechnology 35 (3), 280-284, 2017 | 311 | 2017 |
| Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c B Pan, C Askew, A Galvin, S Heman-Ackah, Y Asai, AA Indzhykulian, ... Nature biotechnology 35 (3), 264-272, 2017 | 279 | 2017 |
| Tmc gene therapy restores auditory function in deaf mice C Askew, C Rochat, B Pan, Y Asai, H Ahmed, E Child, BL Schneider, ... Science translational medicine 7 (295), 295ra108-295ra108, 2015 | 259 | 2015 |
| The postnatal accumulation of junctional E-cadherin is inversely correlated with the capacity for supporting cells to convert directly into sensory hair cells in mammalian … MS Collado, BR Thiede, W Baker, C Askew, LM Igbani, JT Corwin Journal of Neuroscience 31 (33), 11855-11866, 2011 | 68 | 2011 |
| The mechanosensory structure of the hair cell requires clarin-1, a protein encoded by Usher syndrome III causative gene R Geng, S Melki, DHC Chen, G Tian, DN Furness, T Oshima-Takago, ... Journal of Neuroscience 32 (28), 9485-9498, 2012 | 65 | 2012 |
| Deletion of PDZD7 disrupts the Usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice J Zou, T Zheng, C Ren, C Askew, XP Liu, B Pan, JR Holt, Y Wang, J Yang Human molecular genetics 23 (9), 2374-2390, 2014 | 62 | 2014 |
| Hair cell and neural contributions to the cochlear summating potential AK Pappa, KA Hutson, WC Scott, JD Wilson, KE Fox, MM Masood, ... Journal of neurophysiology 121 (6), 2163-2180, 2019 | 55 | 2019 |
| Localization and expression of clarin-1, the Clrn1 gene product, in auditory hair cells and photoreceptors M Zallocchi, DT Meehan, D Delimont, C Askew, S Garige, MA Gratton, ... Hearing research 255 (1-2), 109-120, 2009 | 51 | 2009 |
| Matrix metalloproteinase dysregulation in the stria vascularis of mice with Alport syndrome: implications for capillary basement membrane pathology MA Gratton, VH Rao, DT Meehan, C Askew, D Cosgrove The American journal of pathology 166 (5), 1465-1474, 2005 | 48 | 2005 |
| Adeno-associated virus gene replacement for recessive inner ear dysfunction: Progress and challenges C Askew, WW Chien Hearing research 394, 107947, 2020 | 28 | 2020 |
| Development of AAV variants with human hepatocyte tropism and neutralizing antibody escape capacity X Pei, W Shao, A Xing, C Askew, X Chen, C Cui, YL Abajas, DA Gerber, ... Molecular Therapy Methods & Clinical Development 18, 259-268, 2020 | 27 | 2020 |
| Superior human hepatocyte transduction with adeno-associated virus vector serotype 7 W Shao, X Pei, C Cui, C Askew, A Dobbins, X Chen, YL Abajas, ... Gene therapy 26 (12), 504-514, 2019 | 17 | 2019 |
| Grxcr2 is required for stereocilia morphogenesis in the cochlea MR Avenarius, JY Jung, C Askew, SM Jones, KL Hunker, H Azaiez, ... PloS one 13 (8), e0201713, 2018 | 13 | 2018 |
| Customized blood-brain barrier shuttle peptide to increase AAV9 vector crossing the BBB and augment transduction in the brain X Zhang, Z Chai, AL Dobbins, MS Itano, C Askew, Z Miao, H Niu, ... Biomaterials 281, 121340, 2022 | 9 | 2022 |
| Self-complementarity in adeno-associated virus enhances transduction and gene expression in mouse cochlear tissues G Casey, C Askew, MA Brimble, RJ Samulski, AM Davidoff, C Li, ... Plos one 15 (11), e0242599, 2020 | 5 | 2020 |
| A Vector Independent Method of Neutralizing Antibody Evasion Potently Protects AAV for Efficient Gene Delivery C Askew, C Li Molecular Therapy 28 (4), 22-22, 2020 | 3 | 2020 |
| Compositions and methods for binding antibodies and inhibiting neutralizing antibodies C Li, C Askew, B Kuhlman, DF Thieker | 1 | 2021 |
| Elastin‐Like Polypeptides Facilitate Adeno‐Associated Virus Transduction in the Presence of Pre‐Existing Neutralizing Antibodies K Wang, M Zheng, C Askew, X Zhang, C Li, Z Han Advanced Therapeutics, 2022 | | 2022 |
| Engineered Protein M Analogs Enhance the Ability to Suppress Vector Neutralizing Antibodies and Generate a Window for Successful Gene Delivery C Askew, D Thieker, Z Chai, B Kuhlman, C Li MOLECULAR THERAPY 29 (4), 91-91, 2021 | | 2021 |
| Elastin-Like Polypeptide Mediated AAV Delivery Improved Transduction Efficiency and Reduced Immune Response K Wang, M Zheng, C Askew, C Li, Z Han MOLECULAR THERAPY 28 (4), 24-24, 2020 | | 2020 |
