Intrinsic antibiotic resistance: mechanisms, origins, challenges and solutions G Cox, GD Wright International Journal of Medical Microbiology 303 (6-7), 287-292, 2013 | 373 | 2013 |
Plazomicin retains antibiotic activity against most aminoglycoside modifying enzymes G Cox, L Ejim, PJ Stogios, K Koteva, E Bordeleau, E Evdokimova, ... ACS infectious diseases 4 (6), 980-987, 2018 | 59 | 2018 |
A common platform for antibiotic dereplication and adjuvant discovery G Cox, A Sieron, AM King, G De Pascale, AC Pawlowski, K Koteva, ... Cell chemical biology 24 (1), 98-109, 2017 | 47 | 2017 |
Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid G Cox, GS Thompson, HT Jenkins, F Peske, A Savelsbergh, MV Rodnina, ... Proceedings of the National Academy of Sciences 109 (6), 2102-2107, 2012 | 44 | 2012 |
Inhibition of the ANT (2 ″)-Ia resistance enzyme and rescue of aminoglycoside antibiotic activity by synthetic α-hydroxytropolones DR Hirsch, G Cox, MP D’Erasmo, T Shakya, C Meck, N Mohd, GD Wright, ... Bioorganic & medicinal chemistry letters 24 (21), 4943-4947, 2014 | 39 | 2014 |
An unusual class of anthracyclines potentiate Gram-positive antibiotics in intrinsically resistant Gram-negative bacteria G Cox, K Koteva, GD Wright Journal of Antimicrobial Chemotherapy 69 (7), 1844-1855, 2014 | 38 | 2014 |
Structural and molecular basis for resistance to aminoglycoside antibiotics by the adenylyltransferase ANT (2 ″)-Ia G Cox, PJ Stogios, A Savchenko, GD Wright MBio 6 (1), 2015 | 37 | 2015 |
Rifampin phosphotransferase is an unusual antibiotic resistance kinase PJ Stogios, G Cox, P Spanogiannopoulos, MC Pillon, N Waglechner, ... Nature communications 7, 11343, 2016 | 26 | 2016 |
Rox, a rifamycin resistance Enzyme with an unprecedented mechanism of action K Koteva, G Cox, JK Kelso, MD Surette, HL Zubyk, L Ejim, P Stogios, ... Cell chemical biology 25 (4), 403-412. e5, 2018 | 18 | 2018 |
“tet (U)” is not a tetracycline resistance determinant JA Caryl, G Cox, S Trimble, AJ O'Neill Antimicrobial agents and chemotherapy 56 (6), 3378-3379, 2012 | 17 | 2012 |
Substrate Recognition by a Colistin Resistance Enzyme from Moraxella catarrhalis PJ Stogios, G Cox, HL Zubyk, E Evdokimova, Z Wawrzak, GD Wright, ... ACS chemical biology 13 (5), 1322-1332, 2018 | 13 | 2018 |
Mutagenesis mapping of the protein-protein interaction underlying FusB-type fusidic acid resistance G Cox, TA Edwards, AJ O'Neill Antimicrobial agents and chemotherapy 57 (10), 4640-4644, 2013 | 6 | 2013 |
Bacterial Anti-adhesives: Inhibition of Staphylococcus aureus Nasal Colonization AC Leonard, LE Petrie, G Cox ACS infectious diseases 5 (10), 1668-1681, 2019 | 5 | 2019 |
The evolutionary conservation of Escherichia coli drug efflux pumps supports physiological functions T Teelucksingh, LK Thompson, G Cox Journal of Bacteriology 202 (22), 2020 | 2 | 2020 |
Antibiotic Dereplication Using the Antibiotic Resistance Platform. HL Zubyk, G Cox, GD Wright Journal of visualized experiments: JoVE, 2019 | 2 | 2019 |
Development and validation of a high-throughput whole cell assay to investigate Staphylococcus aureus adhesion to host ligands LE Petrie, AC Leonard, J Murphy, G Cox Journal of Biological Chemistry 295 (49), 16700-16712, 2020 | 1 | 2020 |
Full wwPDB X-ray Structure Validation Report i Y Wang Word wide protein data bank, 2009 | 1 | 2009 |
Old Problems and New Solutions: Antibiotic Alternatives in Food Animal Production C Stoica, G Cox Canadian Journal of Microbiology, 2021 | | 2021 |
Resistance-Guided Discovery of Elfamycin Antibiotic Producers with Antigonococcal Activity V Yarlagadda, R Medina, TA Johnson, KP Koteva, G Cox, MN Thaker, ... ACS Infectious Diseases 6 (12), 3163-3173, 2020 | | 2020 |
Full wwPDB X-ray Structure Validation Report i K Das, E Arnold | | |