Cannabinoid CB2 receptors and fatty acid amide hydrolase are selectively overexpressed in neuritic plaque-associated glia in Alzheimer's disease brains C Benito, E Núñez, RM Tolón, EJ Carrier, A Rábano, CJ Hillard, J Romero Journal of Neuroscience 23 (35), 11136-11141, 2003 | 802 | 2003 |
Cannabinoid CB2 receptor: a new target for controlling neural cell survival? J Fernandez-Ruiz, J Romero, G Velasco, RM Tolon, JA Ramos, ... Trends in pharmacological sciences 28 (1), 39-45, 2007 | 466 | 2007 |
Cannabinoid CB2 receptors are expressed by perivascular microglial cells in the human brain: An immunohistochemical study E Núñez, C Benito, MR Pazos, A Barbachano, O Fajardo, S González, ... Synapse 53 (4), 208-213, 2004 | 464 | 2004 |
Cannabinoid CB2 receptors in human brain inflammation C Benito, RM Tolón, MR Pazos, E Núñez, AI Castillo, J Romero British journal of pharmacology 153 (2), 277-285, 2008 | 379 | 2008 |
Cannabinoid CB1 and CB2 receptors and fatty acid amide hydrolase are specific markers of plaque cell subtypes in human multiple sclerosis C Benito, JP Romero, RM Tolón, D Clemente, F Docagne, CJ Hillard, ... Journal of Neuroscience 27 (9), 2396-2402, 2007 | 296 | 2007 |
Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: Relevance for Huntington's disease O Sagredo, S González, I Aroyo, MR Pazos, C Benito, I Lastres‐Becker, ... Glia 57 (11), 1154-1167, 2009 | 212 | 2009 |
A glial endogenous cannabinoid system is upregulated in the brains of macaques with simian immunodeficiency virus-induced encephalitis C Benito, WK Kim, I Chavarría, CJ Hillard, K Mackie, RM Tolón, K Williams, ... Journal of Neuroscience 25 (10), 2530-2536, 2005 | 188 | 2005 |
The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages RM Tolón, E Núñez, MR Pazos, C Benito, AI Castillo, JA Martínez-Orgado, ... Brain research 1283, 148-154, 2009 | 175 | 2009 |
Functional neuroanatomy of the endocannabinoid system MR Pazos, E Núñez, C Benito, RM Tolón, J Romero Pharmacology Biochemistry and Behavior 81 (2), 239-247, 2005 | 166 | 2005 |
A double-blind, randomized, cross-over, placebo-controlled, pilot trial with Sativex in Huntington’s disease JL López-Sendón Moreno, J García Caldentey, P Trigo Cubillo, ... Journal of neurology 263, 1390-1400, 2016 | 154 | 2016 |
Cannabidiol reduces lipopolysaccharide-induced vascular changes and inflammation in the mouse brain: an intravital microscopy study L Ruiz-Valdepeñas, JA Martínez-Orgado, C Benito, Á Millán, RM Tolón, ... Journal of neuroinflammation 8, 1-10, 2011 | 143 | 2011 |
Cannabinoid CB2 receptors in the mouse brain: relevance for Alzheimer’s disease A López, N Aparicio, MR Pazos, MT Grande, MA Barreda-Manso, ... Journal of neuroinflammation 15, 1-11, 2018 | 132 | 2018 |
Cannabinoid pharmacology/therapeutics in chronic degenerative disorders affecting the central nervous system MS Aymerich, E Aso, MA Abellanas, RM Tolon, JA Ramos, I Ferrer, ... Biochemical pharmacology 157, 67-84, 2018 | 113 | 2018 |
Glial expression of cannabinoid CB2 receptors and fatty acid amide hydrolase are beta amyloid–linked events in Down’s syndrome E Nunez, C Benito, RM Tolon, CJ Hillard, WST Griffin, J Romero Neuroscience 151 (1), 104-110, 2008 | 106 | 2008 |
Role of the endocannabinoid system in Alzheimer's disease: new perspectives MR Pazos, E Nunez, C Benito, RM Tolon, J Romero Life sciences 75 (16), 1907-1915, 2004 | 99 | 2004 |
β− Amyloid exacerbates inflammation in astrocytes lacking fatty acid amide hydrolase through a mechanism involving PPAR‐α, PPAR‐γ and TRPV1, but not CB1 or CB2 receptors C Benito, RM Tolón, AI Castillo, L Ruiz‐Valdepeñas, JA Martínez‐Orgado, ... British journal of pharmacology 166 (4), 1474-1489, 2012 | 98 | 2012 |
The cannabinoid agonist WIN55212 reduces brain damage in an in vivo model of hypoxic-ischemic encephalopathy in newborn rats D Fernández-López, MR Pazos, RM Tolon, M Moro, J Romero, ... Pediatric research 62 (3), 255-260, 2007 | 92 | 2007 |
Growth hormone induces somatostatin and insulin-like growth factor I gene expression in the cerebral hemispheres of aging rats J Lopez-Fernandez, F Sanchez-Franco, B Velasco, RM Tolon, F Pazos, ... Endocrinology 137 (10), 4384-4391, 1996 | 82 | 1996 |
Synergistic activation of the prolactin promoter by vitamin D receptor and GHF-1: role of the coactivators, CREB-binding protein and steroid hormone receptor coactivator-1 (SRC-1) AI Castillo, AM Jimenez-Lara, RM Tolon, A Aranda Molecular Endocrinology 13 (7), 1141-1154, 1999 | 74 | 1999 |
The endocannabinoid system and Alzheimer’s disease C Benito, E Núñez, MR Pazos, RM Tolón, J Romero Molecular neurobiology 36, 75-81, 2007 | 72 | 2007 |