Rosa Tolón rafael
Rosa Tolón rafael
Profesor de Farmacia. Universidad Francisco de Vitoria
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Cannabinoid CB2 receptors and fatty acid amide hydrolase are selectively overexpressed in neuritic plaque-associated glia in Alzheimer's disease brains
C Benito, E Núñez, RM Tolón, EJ Carrier, A Rábano, CJ Hillard, J Romero
Journal of Neuroscience 23 (35), 11136-11141, 2003
Cannabinoid CB2 receptor: a new target for controlling neural cell survival?
J Fernández-Ruiz, J Romero, G Velasco, RM Tolón, JA Ramos, ...
Trends in pharmacological sciences 28 (1), 39-45, 2007
Cannabinoid CB2 receptors are expressed by perivascular microglial cells in the human brain: An immunohistochemical study
E Núñez, C Benito, MR Pazos, A Barbachano, O Fajardo, S González, ...
Synapse 53 (4), 208-213, 2004
Cannabinoid CB2 receptors in human brain inflammation
C Benito, RM Tolon, MR Pazos, E Nunez, AI Castillo, J Romero
British journal of pharmacology 153 (2), 277-285, 2008
Cannabinoid CB1 and CB2 receptors and fatty acid amide hydrolase are specific markers of plaque cell subtypes in human multiple sclerosis
C Benito, JP Romero, RM Tolón, D Clemente, F Docagne, CJ Hillard, ...
Journal of Neuroscience 27 (9), 2396-2402, 2007
Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: Relevance for Huntington's disease
O Sagredo, S González, I Aroyo, MR Pazos, C Benito, I Lastres‐Becker, ...
Glia 57 (11), 1154-1167, 2009
A glial endogenous cannabinoid system is upregulated in the brains of macaques with simian immunodeficiency virus-induced encephalitis
C Benito, WK Kim, I Chavarría, CJ Hillard, K Mackie, RM Tolón, K Williams, ...
Journal of Neuroscience 25 (10), 2530-2536, 2005
Functional neuroanatomy of the endocannabinoid system
MR Pazos, E Núñez, C Benito, RM Tolón, J Romero
Pharmacology Biochemistry and Behavior 81 (2), 239-247, 2005
The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages
RM Tolón, E Núñez, MR Pazos, C Benito, AI Castillo, JA Martínez-Orgado, ...
Brain research 1283, 148-154, 2009
Cannabidiol reduces lipopolysaccharide-induced vascular changes and inflammation in the mouse brain: an intravital microscopy study
L Ruiz-Valdepeñas, JA Martínez-Orgado, C Benito, Á Millán, RM Tolón, ...
Journal of neuroinflammation 8 (1), 1-10, 2011
Role of the endocannabinoid system in Alzheimer's disease: new perspectives
MR Pazos, E Nunez, C Benito, RM Tolon, J Romero
Life sciences 75 (16), 1907-1915, 2004
A double-blind, randomized, cross-over, placebo-controlled, pilot trial with Sativex in Huntington’s disease
JLLS Moreno, JG Caldentey, PT Cubillo, CR Romero, GG Ribas, ...
Journal of neurology 263 (7), 1390-1400, 2016
Glial expression of cannabinoid CB2 receptors and fatty acid amide hydrolase are beta amyloid–linked events in Down’s syndrome
E Nunez, C Benito, RM Tolon, CJ Hillard, WST Griffin, J Romero
Neuroscience 151 (1), 104-110, 2008
β− Amyloid exacerbates inflammation in astrocytes lacking fatty acid amide hydrolase through a mechanism involving PPAR‐α, PPAR‐γ and TRPV1, but not CB1 or CB2 receptors
C Benito, RM Tolón, AI Castillo, L Ruiz‐Valdepeñas, JA Martínez‐Orgado, ...
British journal of pharmacology 166 (4), 1474-1489, 2012
The cannabinoid agonist WIN55212 reduces brain damage in an in vivo model of hypoxic-ischemic encephalopathy in newborn rats
D Fernández-López, MR Pazos, RM Tolon, MA Moro, J Romero, ...
Pediatric research 62 (3), 255-260, 2007
Growth hormone induces somatostatin and insulin-like growth factor I gene expression in the cerebral hemispheres of aging rats
J Lopez-Fernandez, F Sanchez-Franco, B Velasco, RM Tolon, F Pazos, ...
Endocrinology 137 (10), 4384-4391, 1996
Synergistic activation of the prolactin promoter by vitamin D receptor and GHF-1: role of the coactivators, CREB-binding protein and steroid hormone receptor coactivator-1 (SRC-1)
AI Castillo, AM Jimenez-Lara, RM Tolon, A Aranda
Molecular Endocrinology 13 (7), 1141-1154, 1999
Activation of the prolactin gene by peroxisome proliferator-activated receptor-α appears to be DNA binding-independent
RM Tolón, AI Castillo, A Aranda
Journal of Biological Chemistry 273 (41), 26652-26661, 1998
Cannabinoid pharmacology/therapeutics in chronic degenerative disorders affecting the central nervous system
MS Aymerich, E Aso, MA Abellanas, RM Tolon, JA Ramos, I Ferrer, ...
Biochemical pharmacology 157, 67-84, 2018
Cannabinoid CB 2 receptors in the mouse brain: Relevance for Alzheimer’s disease
A López, N Aparicio, MR Pazos, MT Grande, MA Barreda-Manso, ...
Journal of neuroinflammation 15 (1), 1-11, 2018
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