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Chao Wang
Chao Wang
J David Gladstone Institute, UCSF; UC Berkeley
Dirección de correo verificada de gladstone.ucsf.edu
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Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits
SW Min, X Chen, TE Tracy, Y Li, Y Zhou, C Wang, K Shirakawa, ...
Nature medicine 21 (10), 1154, 2015
4782015
Scalable production of iPSC-derived human neurons to identify tau-lowering compounds by high-content screening
C Wang, ME Ward, R Chen, K Liu, TE Tracy, X Chen, M Xie, PD Sohn, ...
Stem cell reports 9 (4), 1221-1233, 2017
2692017
Transcription Factor–Mediated Differentiation of Human iPSCs into Neurons
MS Fernandopulle, R Prestil, C Grunseich, C Wang, L Gan, ME Ward
Current Protocols in Cell Biology 79 (1), e51, 2018
2502018
Quantitative profiling of endogenous retinoic acid in vivo and in vitro by tandem mass spectrometry
MA Kane, AE Folias, C Wang, JL Napoli
Analytical chemistry 80 (5), 1702-1708, 2008
2472008
Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models
SS Minami, SW Min, G Krabbe, C Wang, Y Zhou, R Asgarov, Y Li, ...
Nature medicine 20 (10), 1157, 2014
2462014
Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss
TE Tracy, PD Sohn, SS Minami, C Wang, SW Min, Y Li, Y Zhou, D Le, I Lo, ...
Neuron 90 (2), 245-260, 2016
2272016
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes
M Song, X Yang, X Ren, L Maliskova, B Li, IR Jones, C Wang, F Jacob, ...
Nature genetics 51 (8), 1252, 2019
1622019
Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain
L Zhan, G Krabbe, F Du, I Jones, MC Reichert, M Telpoukhovskaia, ...
PLoS biology 17 (2), e3000134, 2019
1362019
Endo-lysosomal dysfunction: a converging mechanism in neurodegenerative diseases
LG Chao Wang, Maria A Telpoukhovskaia, Ben A Bahr, Xu Chen
Current Opinion in Neurobiology, 52-58, 2017
134*2017
Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration
TE Tracy, J Madero-Pérez, DL Swaney, TS Chang, M Moritz, C Konrad, ...
Cell 185 (4), 712-728. e14, 2022
1302022
Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy
C Wang, L Fan, RR Khawaja, B Liu, L Zhan, L Kodama, M Chin, Y Li, D Le, ...
Nature communications 13 (1), 1969, 2022
1282022
Cathepsin B degrades amyloid-β in mice expressing wild-type human amyloid precursor protein
C Wang, B Sun, Y Zhou, A Grubb, L Gan
Journal of Biological Chemistry 287 (47), 39834-39841, 2012
1242012
Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice
nature communications, 2021
1192021
Poly (ADP-ribose) polymerase-1 modulates microglial responses to amyloid β
TM Kauppinen, SW Suh, Y Higashi, AE Berman, C Escartin, SJ Won, ...
Journal of neuroinflammation 8 (1), 152, 2011
1102011
Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation
LT Grinberg, X Wang, C Wang, PD Sohn, P Theofilas, M Sidhu, ...
Acta neuropathologica 125 (4), 581-593, 2013
1092013
Reducing acetylated tau is neuroprotective in brain injury
MK Shin, E Vázquez-Rosa, Y Koh, M Dhar, K Chaubey, CJ Cintrón-Pérez, ...
Cell, 2021
1022021
Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes
R Krencik, K Seo, JV van Asperen, N Basu, C Cvetkovic, S Barlas, ...
Stem Cell Reports 9 (6), 1745-1753, 2017
972017
Ethanol elevates physiological all-trans-retinoic acid levels in select loci through altering retinoid metabolism in multiple loci: a potential mechanism of ethanol toxicity
MA Kane, AE Folias, C Wang, JL Napoli
The FASEB Journal 24 (3), 823-832, 2010
932010
Multiple retinol and retinal dehydrogenases catalyze all-trans-retinoic acid biosynthesis in astrocytes
C Wang, MA Kane, JL Napoli
Journal of Biological Chemistry 286 (8), 6542-6553, 2011
792011
Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy
X Chen, Y Li, C Wang, Y Tang, SA Mok, RM Tsai, JC Rojas, A Karydas, ...
Molecular Neurodegeneration 15 (1), 1-19, 2020
752020
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Artículos 1–20