Christopher S. Chen, M.D., Ph.D.
Christopher S. Chen, M.D., Ph.D.
Biomedical Engineering, Boston University; The Wyss Institute for Biologically Inspired Engineeering
Verified email at bu.edu
TitleCited byYear
Geometric control of cell life and death
CS Chen, M Mrksich, S Huang, GM Whitesides, DE Ingber
Science 276 (5317), 1425-1428, 1997
50361997
Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment
R McBeath, DM Pirone, CM Nelson, K Bhadriraju, CS Chen
Developmental cell 6 (4), 483-495, 2004
38152004
Cells lying on a bed of microneedles: an approach to isolate mechanical force
JL Tan, J Tien, DM Pirone, DS Gray, K Bhadriraju, CS Chen
Proceedings of the National Academy of Sciences 100 (4), 1484-1489, 2003
20332003
Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure
AJ Maniotis, CS Chen, DE Ingber
Proceedings of the National Academy of Sciences 94 (3), 849-854, 1997
16461997
Control of stem cell fate by physical interactions with the extracellular matrix
F Guilak, DM Cohen, BT Estes, JM Gimble, W Liedtke, CS Chen
Cell stem cell 5 (1), 17-26, 2009
15552009
Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues
JS Miller, KR Stevens, MT Yang, BM Baker, DHT Nguyen, DM Cohen, ...
Nature materials 11 (9), 768-774, 2012
12042012
Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics
C Grashoff, BD Hoffman, MD Brenner, R Zhou, M Parsons, MT Yang, ...
Nature 466 (7303), 263-266, 2010
10492010
Deconstructing the third dimension–how 3D culture microenvironments alter cellular cues
BM Baker, CS Chen
J Cell Sci 125 (13), 3015-3024, 2012
9762012
Micropatterned surfaces for control of cell shape, position, and function
CS Chen, M Mrksich, S Huang, GM Whitesides, DE Ingber
Biotechnology Progress 14 (3), 356-363, 1998
8721998
Mechanical regulation of cell function with geometrically modulated elastomeric substrates
J Fu, YK Wang, MT Yang, RA Desai, X Yu, Z Liu, CS Chen
Nature methods 7 (9), 733-736, 2010
8662010
Emergent patterns of growth controlled by multicellular form and mechanics
CM Nelson, RP Jean, JL Tan, WF Liu, NJ Sniadecki, AA Spector, ...
Proceedings of the National Academy of Sciences 102 (33), 11594-11599, 2005
7982005
Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels
S Khetan, M Guvendiren, WR Legant, DM Cohen, CS Chen, JA Burdick
Nature materials 12 (5), 458-465, 2013
7022013
Mechanotransduction in development: a growing role for contractility
MA Wozniak, CS Chen
Nature reviews Molecular cell biology 10 (1), 34-43, 2009
6642009
Nanopattern-induced changes in morphology and motility of smooth muscle cells
EKF Yim, RM Reano, SW Pang, AF Yee, CS Chen, KW Leong
Biomaterials 26 (26), 5405-5413, 2005
6312005
Versatile, fully automated, microfluidic cell culture system
R Gomez-Sjoeberg, AA Leyrat, DM Pirone, CS Chen, SR Quake
Analytical chemistry 79 (22), 8557-8563, 2007
6212007
Cell shape provides global control of focal adhesion assembly
CS Chen, JL Alonso, E Ostuni, GM Whitesides, DE Ingber
Biochemical and biophysical research communications 307 (2), 355-361, 2003
6102003
Mechanical tugging force regulates the size of cell–cell junctions
Z Liu, JL Tan, DM Cohen, MT Yang, NJ Sniadecki, SA Ruiz, CM Nelson, ...
Proceedings of the National Academy of Sciences 107 (22), 9944-9949, 2010
6052010
Mechanotransduction at cell-matrix and cell-cell contacts
CS Chen, J Tan, J Tien
Annu. Rev. Biomed. Eng. 6, 275-302, 2004
5882004
Cellular control lies in the balance of forces
ME Chicurel, CS Chen, DE Ingber
Current opinion in cell biology 10 (2), 232-239, 1998
5811998
Controlling cell attachment on contoured surfaces with self-assembled monolayers of alkanethiolates on gold
M Mrksich, CS Chen, Y Xia, LE Dike, DE Ingber, GM Whitesides
Proceedings of the National Academy of Sciences 93 (20), 10775-10778, 1996
5301996
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Articles 1–20