GABAB-receptor subtypes assemble into functional heteromeric complexes K Kaupmann, B Malitschek, V Schuler, J Heid, W Froestl, P Beck, ... Nature 396 (6712), 683-687, 1998 | 1457 | 1998 |
Expression cloning of GABAB receptors uncovers similarity to metabotropic glutamate receptors K Kaupmann, K Huggel, J Heid, PJ Flor, S Bischoff, SJ Mickel, ... Nature 386 (6622), 239-246, 1997 | 1263 | 1997 |
International Union of Pharmacology. XXXIII. Mammalian γ-aminobutyric acidB receptors: structure and function NG Bowery, B Bettler, W Froestl, JP Gallagher, F Marshall, M Raiteri, ... Pharmacological reviews 54 (2), 247-264, 2002 | 798 | 2002 |
Epilepsy, hyperalgesia, impaired memory, and loss of pre-and postsynaptic GABAB responses in mice lacking GABAB (1) V Schuler, C Lüscher, C Blanchet, N Klix, G Sansig, K Klebs, M Schmutz, ... Neuron 31 (1), 47-58, 2001 | 646 | 2001 |
Genetic and pharmacological evidence of a role for GABAB receptors in the modulation of anxiety-and antidepressant-like behavior C Mombereau, K Kaupmann, W Froestl, G Sansig, H van der Putten, ... Neuropsychopharmacology 29 (6), 1050-1062, 2004 | 430 | 2004 |
C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABAB receptors A Pagano, G Rovelli, J Mosbacher, T Lohmann, B Duthey, D Stauffer, ... Journal of Neuroscience 21 (4), 1189-1202, 2001 | 373 | 2001 |
CGP 35348: a centrally active blocker of GABAB receptors HR Olpe, G Karlsson, MF Pozza, F Brugger, M Steinmann, H Van Riezen, ... European journal of pharmacology 187 (1), 27-38, 1990 | 357 | 1990 |
Positive allosteric modulation of native and recombinant γ-aminobutyric acidB receptors by 2, 6-di-tert-butyl-4-(3-hydroxy-2, 2-dimethyl-propyl)-phenol (CGP7930) and its … S Urwyler, J Mosbacher, K Lingenhoehl, J Heid, K Hofstetter, W Froestl, ... Molecular pharmacology 60 (5), 963-971, 2001 | 302 | 2001 |
Phosphinic acid analogs of GABA. 2. Selective, orally active GABAB antagonists W Froestl, SJ Mickel, G von Sprecher, PJ Diel, RG Hall, L Maier, D Strub, ... Journal of medicinal chemistry 38 (17), 3313-3331, 1995 | 301 | 1995 |
Redistribution of GABAB (1) protein and atypical GABAB responses in GABAB (2)-deficient mice M Gassmann, H Shaban, R Vigot, G Sansig, C Haller, S Barbieri, ... Journal of Neuroscience 24 (27), 6086-6097, 2004 | 278 | 2004 |
Phosphinic acid analogs of GABA. 1. New potent and selective GABAB agonists W Froestl, SJ Mickel, RG Hall, G von Sprecher, D Strub, PA Baumann, ... Journal of medicinal chemistry 38 (17), 3297-3312, 1995 | 263 | 1995 |
Mutagenesis and modeling of the GABAB receptor extracellular domain support a venus flytrap mechanism for ligand binding T Galvez, ML Parmentier, C Joly, B Malitschek, K Kaupmann, R Kuhn, ... Journal of Biological Chemistry 274 (19), 13362-13369, 1999 | 258 | 1999 |
The effects of GABAB agonists and gabapentin on mechanical hyperalgesia in models of neuropathic and inflammatory pain in the rat S Patel, S Naeem, A Kesingland, W Froestl, M Capogna, L Urban, A Fox Pain 90 (3), 217-226, 2001 | 246 | 2001 |
Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N, N′-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4, 6-diamine): anxiolytic-like … JF Cryan, PH Kelly, F Chaperon, C Gentsch, C Mombereau, ... Journal of Pharmacology and Experimental Therapeutics 310 (3), 952-963, 2004 | 237 | 2004 |
γ-Hydroxybutyrate is a weak agonist at recombinant GABAB receptors K Lingenhoehl, R Brom, J Heid, P Beck, W Froestl, K Kaupmann, B Bettler, ... Neuropharmacology 38 (11), 1667-1673, 1999 | 229 | 1999 |
SGS742: the first GABAB receptor antagonist in clinical trials W Froestl, M Gallagher, H Jenkins, A Madrid, T Melcher, S Teichman, ... Biochemical pharmacology 68 (8), 1479-1487, 2004 | 227 | 2004 |
N, N′-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4, 6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of γ-aminobutyric acidB receptor … S Urwyler, MF Pozza, K Lingenhoehl, J Mosbacher, C Lampert, W Froestl, ... Journal of Pharmacology and Experimental Therapeutics 307 (1), 322-330, 2003 | 219 | 2003 |
Specific γ‐hydroxybutyrate‐binding sites but loss of pharmacological effects of γ‐hydroxybutyrate in GABAB(1)‐deficient mice K Kaupmann, JF Cryan, P Wellendorph, C Mombereau, G Sansig, ... European Journal of Neuroscience 18 (10), 2722-2730, 2003 | 218 | 2003 |
Human γ-aminobutyric acid type B receptors are differentially expressed and regulate inwardly rectifying K+ channels K Kaupmann, V Schuler, J Mosbacher, S Bischoff, H Bittiger, J Heid, ... Proceedings of the National Academy of Sciences 95 (25), 14991-14996, 1998 | 203 | 1998 |
Pharmacologic rescue of lethal seizures in mice deficient in succinate semialdehyde dehydrogenase BM Hogema, M Gupta, H Senephansiri, TG Burlingame, M Taylor, ... Nature genetics 29 (2), 212-216, 2001 | 188 | 2001 |