Wolfgang Froestl
Wolfgang Froestl
AC Immune SA, Lausanne, Switzerland
Verified email at acimmune.com
Cited by
Cited by
GABA B-receptor subtypes assemble into functional heteromeric complexes
K Kaupmann, B Malitschek, V Schuler, J Heid, W Froestl, P Beck, ...
Nature 396 (6712), 683-687, 1998
Expression cloning of GABA B receptors uncovers similarity to metabotropic glutamate receptors
K Kaupmann, K Huggel, J Heid, PJ Flor, S Bischoff, SJ Mickel, ...
Nature 386 (6622), 239-246, 1997
Cellular regulation of RGS proteins: modulators and integrators of G protein signaling
S Hollinger, JR Hepler
Pharmacological reviews 54 (3), 527-559, 2002
International Union of Pharmacology. XXXIII. Mammalian γ-aminobutyric acidB receptors: structure and function
NG Bowery, B Bettler, W Froestl, JP Gallagher, F Marshall, M Raiteri, ...
Pharmacological reviews 54 (2), 247-264, 2002
Epilepsy, hyperalgesia, impaired memory, and loss of pre-and postsynaptic GABAB responses in mice lacking GABAB (1)
V Schuler, C Lüscher, C Blanchet, N Klix, G Sansig, K Klebs, M Schmutz, ...
Neuron 31 (1), 47-58, 2001
International Union of Pharmacology. XXX. Update on chemokine receptor nomenclature
PM Murphy
Pharmacological reviews 54 (2), 227-229, 2002
Genetic and pharmacological evidence of a role for GABA B receptors in the modulation of anxiety-and antidepressant-like behavior
C Mombereau, K Kaupmann, W Froestl, G Sansig, H van der Putten, ...
Neuropsychopharmacology 29 (6), 1050-1062, 2004
C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABAB receptors
A Pagano, G Rovelli, J Mosbacher, T Lohmann, B Duthey, D Stauffer, ...
Journal of Neuroscience 21 (4), 1189-1202, 2001
CGP 35348: a centrally active blocker of GABAB receptors
HR Olpe, G Karlsson, MF Pozza, F Brugger, M Steinmann, H Van Riezen, ...
European journal of pharmacology 187 (1), 27-38, 1990
Positive allosteric modulation of native and recombinant γ-aminobutyric acidB receptors by 2, 6-di-tert-butyl-4-(3-hydroxy-2, 2-dimethyl-propyl)-phenol (CGP7930) and its …
S Urwyler, J Mosbacher, K Lingenhoehl, J Heid, K Hofstetter, W Froestl, ...
Molecular Pharmacology 60 (5), 963-971, 2001
Phosphinic acid analogs of GABA. 2. Selective, orally active GABAB antagonists
W Froestl, SJ Mickel, G von Sprecher, PJ Diel, RG Hall, L Maier, D Strub, ...
Journal of medicinal chemistry 38 (17), 3313-3331, 1995
Phosphinic acid analogs of GABA. 1. New potent and selective GABAB agonists
W Froestl, SJ Mickel, RG Hall, G von Sprecher, D Strub, PA Baumann, ...
Journal of medicinal chemistry 38 (17), 3297-3312, 1995
Mutagenesis and modeling of the GABAB receptor extracellular domain support a venus flytrap mechanism for ligand binding
T Galvez, ML Parmentier, C Joly, B Malitschek, K Kaupmann, R Kuhn, ...
Journal of Biological Chemistry 274 (19), 13362-13369, 1999
Redistribution of GABAB (1) protein and atypical GABAB responses in GABAB (2)-deficient mice
M Gassmann, H Shaban, R Vigot, G Sansig, C Haller, S Barbieri, ...
Journal of Neuroscience 24 (27), 6086-6097, 2004
The effects of GABAB agonists and gabapentin on mechanical hyperalgesia in models of neuropathic and inflammatory pain in the rat
S Patel, S Naeem, A Kesingland, W Froestl, M Capogna, L Urban, A Fox
Pain 90 (3), 217-226, 2001
Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N, N′-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4, 6-diamine): anxiolytic-like …
JF Cryan, PH Kelly, F Chaperon, C Gentsch, C Mombereau, ...
Journal of Pharmacology and Experimental Therapeutics 310 (3), 952-963, 2004
γ-Hydroxybutyrate is a weak agonist at recombinant GABAB receptors
K Lingenhoehl, R Brom, J Heid, P Beck, W Froestl, K Kaupmann, B Bettler, ...
Neuropharmacology 38 (11), 1667-1673, 1999
SGS742: the first GABAB receptor antagonist in clinical trials
W Froestl, M Gallagher, H Jenkins, A Madrid, T Melcher, S Teichman, ...
Biochemical pharmacology 68 (8), 1479-1487, 2004
N, N′-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4, 6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of γ-aminobutyric acidB receptor …
S Urwyler, MF Pozza, K Lingenhoehl, J Mosbacher, C Lampert, W Froestl, ...
Journal of Pharmacology and Experimental Therapeutics 307 (1), 322-330, 2003
Specific γ‐hydroxybutyrate‐binding sites but loss of pharmacological effects of γ‐hydroxybutyrate in GABAB(1)‐deficient mice
K Kaupmann, JF Cryan, P Wellendorph, C Mombereau, G Sansig, ...
European Journal of Neuroscience 18 (10), 2722-2730, 2003
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