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| The nuclear receptor LXR is a glucose sensor N Mitro, PA Mak, L Vargas, C Godio, E Hampton, V Molteni, A Kreusch, ... Nature 445 (7124), 219-223, 2007 | 701 | 2007 |
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| Ligand and target discovery by fragment-based screening in human cells CG Parker, A Galmozzi, Y Wang, BE Correia, K Sasaki, CM Joslyn, ... Cell 168 (3), 527-541. e29, 2017 | 409 | 2017 |
| T0901317 is a potent PXR ligand: implications for the biology ascribed to LXR N Mitro, L Vargas, R Romeo, A Koder, E Saez FEBS letters 581 (9), 1721-1726, 2007 | 285 | 2007 |
| Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue A Galmozzi, N Mitro, A Ferrari, E Gers, F Gilardi, C Godio, G Cermenati, ... diabetes 62 (3), 732-742, 2013 | 262 | 2013 |
| PPARγ signaling exacerbates mammary gland tumor development E Saez, J Rosenfeld, A Livolsi, P Olson, E Lombardo, M Nelson, ... Genes & development 18 (5), 528-540, 2004 | 260 | 2004 |
| Arylfluorosulfates inactivate intracellular lipid binding protein (s) through chemoselective SuFEx reaction with a binding site Tyr residue W Chen, J Dong, L Plate, DE Mortenson, GJ Brighty, S Li, Y Liu, ... Journal of the American Chemical Society 138 (23), 7353-7364, 2016 | 251 | 2016 |
| c-Fos is required for malignant progression of skin tumors E Saez, SE Rutberg, E Mueller, H Oppenheim, J Smoluk, SH Yuspa, ... Cell 82 (5), 721-732, 1995 | 245 | 1995 |
| Telomere-independent Rap1 is an IKK adaptor and regulates NF-κB-dependent gene expression H Teo, S Ghosh, H Luesch, A Ghosh, ET Wong, N Malik, A Orth, ... Nature cell biology 12 (8), 758-767, 2010 | 244 | 2010 |
| The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARγ expression H Waki, KW Park, N Mitro, L Pei, R Damoiseaux, DC Wilpitz, K Reue, ... Cell metabolism 5 (5), 357-370, 2007 | 244 | 2007 |
| Chemical proteomics identifies druggable vulnerabilities in a genetically defined cancer L Bar-Peled, EK Kemper, RM Suciu, EV Vinogradova, KM Backus, ... Cell 171 (3), 696-709. e23, 2017 | 240 | 2017 |
| Inducible gene expression in mammalian cells and transgenic mice E Saez, D No, A West, RM Evans Current opinion in biotechnology 8 (5), 608-616, 1997 | 190 | 1997 |
| Identification of ligands and coligands for the ecdysone-regulated gene switch E Saez, MC Nelson, B Eshelman, E Banayo, A Koder, GJ Cho, RM Evans Proceedings of the National Academy of Sciences 97 (26), 14512-14517, 2000 | 186 | 2000 |
| Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs CJ Villanueva, L Vergnes, J Wang, BG Drew, C Hong, Y Tu, Y Hu, X Peng, ... Cell metabolism 17 (3), 423-435, 2013 | 179 | 2013 |
| TLE3 is a dual-function transcriptional coregulator of adipogenesis CJ Villanueva, H Waki, C Godio, R Nielsen, WL Chou, L Vargas, ... Cell metabolism 13 (4), 413-427, 2011 | 165 | 2011 |
| Don't know much bile-ology A Chawla, E Saez, RM Evans Cell 103 (1), 1-4, 2000 | 157 | 2000 |
| Differentiation of mouse keratinocytes is accompanied by PKC-dependent changes in AP-1 proteins. SE Rutberg, E Saez, A Glick, AA Dlugosz, BM Spiegelman, SH Yuspa Oncogene 13 (1), 167-176, 1996 | 148 | 1996 |
| Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes E Dominguez, A Galmozzi, JW Chang, KL Hsu, J Pawlak, W Li, C Godio, ... Nature chemical biology 10 (2), 113-121, 2014 | 144 | 2014 |
