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RUI KONG
RUI KONG
Emory Vaccine Center
Dirección de correo verificada de emory.edu
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Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
NA Doria-Rose, CA Schramm, J Gorman, PL Moore, JN Bhiman, ...
Nature 509 (7498), 55-62, 2014
7822014
Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G
GBE Stewart-Jones, C Soto, T Lemmin, GY Chuang, A Druz, R Kong, ...
Cell 165 (4), 813-826, 2016
4122016
Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody
R Kong, K Xu, T Zhou, P Acharya, T Lemmin, K Liu, G Ozorowski, C Soto, ...
Science 352 (6287), 828-833, 2016
3282016
Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors
T Zhou, RM Lynch, L Chen, P Acharya, X Wu, NA Doria-Rose, MG Joyce, ...
Cell 161 (6), 1280-1292, 2015
3162015
Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody
M Bonsignori, T Zhou, Z Sheng, L Chen, F Gao, MG Joyce, G Ozorowski, ...
Cell 165 (2), 449-463, 2016
3152016
Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1
K Xu, P Acharya, R Kong, C Cheng, GY Chuang, K Liu, MK Louder, ...
Nature medicine 24 (6), 857, 2018
2752018
Envelope residue 375 substitutions in simian–human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques
H Li, S Wang, R Kong, W Ding, FH Lee, Z Parker, E Kim, GH Learn, ...
Proceedings of the National Academy of Sciences 113 (24), E3413-E3422, 2016
2022016
Optimal combinations of broadly neutralizing antibodies for prevention and treatment of HIV-1 clade C infection
K Wagh, T Bhattacharya, C Williamson, A Robles, M Bayne, J Garrity, ...
PLoS pathogens 12 (3), e1005520, 2016
1862016
Improving Neutralization potency and breadth by combining broadly reactive HIV-1 antibodies targeting major neutralization epitopes
R Kong, MK Louder, K Wagh, RT Bailer, K Greene, H Gao, JD Taft, ...
Journal of virology 89 (5), 2659-2671, 2015
1382015
Functional interrogation and mining of natively paired human VH:VL antibody repertoires
B Wang, BJ DeKosky, MR Timm, J Lee, E Normandin, J Misasi, R Kong, ...
Nature biotechnology 36 (2), 152, 2018
1222018
Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization
R Kong, H Duan, Z Sheng, K Xu, P Acharya, X Chen, C Cheng, ...
Cell 178 (3), 567-584. e19, 2019
1042019
Gene-specific substitution profiles describe the types and frequencies of amino acid changes during antibody somatic hypermutation
Z Sheng, CA Schramm, R Kong, JC Mullikin, JR Mascola, PD Kwong, ...
Frontiers in immunology 8, 537, 2017
792017
A neutralizing antibody recognizing primarily N-linked glycan targets the silent face of the HIV envelope
T Zhou, A Zheng, U Baxa, GY Chuang, IS Georgiev, R Kong, S O’Dell, ...
Immunity 48 (3), 500-513. e6, 2018
782018
Broad and potent neutralizing antibody responses elicited in natural HIV-2 infection
R Kong, H Li, F Bibollet-Ruche, JM Decker, NN Zheng, GS Gottlieb, ...
Journal of virology 86 (2), 947-960, 2012
782012
Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting
NA Doria-Rose, HR Altae-Tran, RS Roark, SD Schmidt, MS Sutton, ...
PLoS pathogens 13 (1), e1006148, 2017
582017
Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting
C Cheng, K Xu, R Kong, GY Chuang, AR Corrigan, H Geng, KR Hill, ...
PloS one 14 (4), e0215163, 2019
442019
Epitope mapping of broadly neutralizing human HIV-2 monoclonal antibodies
R Kong, H Li, I Georgiev, A Changela, F Bibollet-Ruche, JM Decker, ...
Journal of Virology, 2012
35*2012
Preclinical development of a fusion peptide conjugate as an HIV vaccine immunogen
L Ou, WP Kong, GY Chuang, M Ghosh, K Gulla, S O’Dell, J Varriale, ...
Scientific reports 10 (1), 1-13, 2020
342020
Development of a 3mut-apex-stabilized envelope trimer that expands HIV-1 neutralization breadth when used to boost fusion peptide-directed vaccine-elicited responses
GY Chuang, YT Lai, JC Boyington, C Cheng, H Geng, S Narpala, R Rawi, ...
Journal of virology 94 (13), e00074-20, 2020
232020
VRC34-Antibody lineage development reveals how a required rare mutation shapes the maturation of a broad HIV-neutralizing lineage
CH Shen, BJ DeKosky, Y Guo, K Xu, Y Gu, D Kilam, SH Ko, R Kong, K Liu, ...
Cell host & microbe 27 (4), 531-543. e6, 2020
202020
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