Orally active aminopeptidase A inhibitors reduce blood pressure: a new strategy for treating hypertension L Bodineau, A Frugiere, Y Marc, N Inguimbert, C Fassot, F Balavoine, ... Hypertension 51 (5), 1318-1325, 2008 | 74 | 2008 |
On-resin cyclization of peptide ligands of the vascular endothelial growth factor receptor 1 by copper (I)-catalyzed 1, 3-dipolar azide–alkyne cycloaddition V Goncalves, B Gautier, A Regazzetti, P Coric, S Bouaziz, C Garbay, ... Bioorganic & medicinal chemistry letters 17 (20), 5590-5594, 2007 | 53 | 2007 |
Targeting the proangiogenic VEGF-VEGFR protein-protein interface with drug-like compounds by in silico and in vitro screening B Gautier, MA Miteva, V Goncalves, F Huguenot, P Coric, S Bouaziz, ... Chemistry & biology 18 (12), 1631-1639, 2011 | 42 | 2011 |
Development of a chemiluminescent screening assay for detection of vascular endothelial growth factor receptor 1 ligands. V Goncalves, B Gautier, C Garbay, M Vidal, N Inguimbert Analytical biochemistry 366 (1), 108-10, 2007 | 41 | 2007 |
Rational design, structure, and biological evaluation of cyclic peptides mimicking the vascular endothelial growth factor V Goncalves, B Gautier, P Coric, S Bouaziz, C Lenoir, C Garbay, M Vidal, ... Journal of medicinal chemistry 50 (21), 5135-5146, 2007 | 37 | 2007 |
Biochemical and structural analysis of the binding determinants of a vascular endothelial growth factor receptor peptidic antagonist B Gautier, V Goncalves, D Diana, R Di Stasi, F Teillet, C Lenoir, ... Journal of medicinal chemistry 53 (11), 4428-4440, 2010 | 36 | 2010 |
N-[2-(Indan-1-yl)-3-mercapto-propionyl] amino acids as highly potent inhibitors of the three vasopeptidases (NEP, ACE, ECE): in vitro and in vivo activities N Inguimbert, H Poras, F Teffo, F Beslot, M Selkti, A Tomas, E Scalbert, ... Bioorganic & medicinal chemistry letters 12 (15), 2001-2005, 2002 | 33 | 2002 |
Immunosensors for estradiol and ethinylestradiol based on new synthetic estrogen derivatives: application to wastewater analysis H Kanso, L Barthelmebs, N Inguimbert, T Noguer Analytical chemistry 85 (4), 2397-2404, 2013 | 27 | 2013 |
Toward an Optimal Joint Recognition of the S1‘ Subsites of Endothelin Converting Enzyme-1 (ECE-1), Angiotensin Converting Enzyme (ACE), and Neutral … N Inguimbert, P Coric, H Poras, H Meudal, F Teffot, MC Fournié-Zaluski, ... Journal of medicinal chemistry 45 (7), 1477-1486, 2002 | 26 | 2002 |
First total synthesis and stereochemical revision of laxaphycin B and its extension to lyngbyacyclamide A F Boyaud, Z Mahiout, C Lenoir, S Tang, J Wdzieczak-Bakala, A Witczak, ... Organic letters 15 (15), 3898-3901, 2013 | 21 | 2013 |
Synthesis and in vitro activities of new non‐peptidic APA Inhibitors N Inguimbert, P Coric, H Dhotel, E Bonnard, C Llorens‐Cortes, N De Mota, ... The Journal of peptide research 65 (2), 175-188, 2005 | 21 | 2005 |
Helical peptides from VEGF and Vammin hotspots for modulating the VEGF–VEGFR interaction MI García-Aranda, S González-López, CM Santiveri, N Gagey-Eilstein, ... Organic & biomolecular chemistry 11 (11), 1896-1905, 2013 | 20 | 2013 |
Disulfide and amide-bridged cyclic peptide analogues of the VEGF81–91 fragment: Synthesis, conformational analysis and biological evaluation MI García-Aranda, Y Mirassou, B Gautier, M Martín-Martínez, N Inguimbert, ... Bioorganic & medicinal chemistry 19 (24), 7526-7533, 2011 | 20 | 2011 |
Asp218 participates with Asp213 to bind a Ca2+ atom into the S1 subsite of aminopeptidase A: a key element for substrate specificity C Claperon, R Rozenfeld, X Iturrioz, N Inguimbert, M Okada, B Roques, ... Biochemical Journal 416 (1), 37-46, 2008 | 20 | 2008 |
Parallel solid-phase synthesis of a small library of linear and hydrocarbon-bridged analogues of VEGF81–91: Potential biological tools for studying the VEGF/VEGFR-1 interaction MI García-Aranda, P Marrero, B Gautier, M Martín-Martínez, N Inguimbert, ... Bioorganic & medicinal chemistry 19 (6), 1978-1986, 2011 | 19 | 2011 |
Structure‐based design of a bicyclic peptide antagonist of the vascular endothelial growth factor receptors V Goncalves, B Gautier, C Garbay, M Vidal, N Inguimbert Journal of peptide science: an official publication of the European Peptide …, 2008 | 17 | 2008 |
Outstanding marine molecules: chemistry, biology, analysis S La Barre, JM Kornprobst John Wiley & Sons, 2014 | 16 | 2014 |
Oxovanadium–salen and–salan complexes as effective labels for electrochemical immunosensing: a case study for estradiol detection H Kanso, N Inguimbert, L Barthelmebs, G Istamboulie, F Thomas, ... Chemical Communications 50 (14), 1658-1661, 2014 | 15 | 2014 |
Efficient microwave-assisted one shot synthesis of peptaibols using inexpensive coupling reagents K Ben Haj Salah, N Inguimbert Organic letters 16 (6), 1783-1785, 2014 | 14 | 2014 |
Exploration of the S subsite of neprilysin: A joined molecular modeling and site‐directed mutagenesis study C Marie‐Claire, G Tiraboschi, E Ruffet, N Inguimbert, MC Fournie‐Zaluski, ... Proteins: Structure, Function, and Bioinformatics 39 (4), 365-371, 2000 | 13 | 2000 |