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Wayne Backes
Wayne Backes
Associate Dean for Research LSU Health Sciences Center- School of Medicine
Dirección de correo verificada de lsuhsc.edu - Página principal
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Origin and health impacts of emissions of toxic by-products and fine particles from combustion and thermal treatment of hazardous wastes and materials
SA Cormier, S Lomnicki, W Backes, B Dellinger
Environmental Health Perspectives 114 (6), 810-817, 2006
2692006
Organization of multiple cytochrome P450s with NADPH-cytochrome P450 reductase in membranes
WL Backes, RW Kelley
Pharmacology & therapeutics 98 (2), 221-233, 2003
1882003
Formation of P450· P450 complexes and their effect on P450 function
JR Reed, WL Backes
Pharmacology & therapeutics 133 (3), 299-310, 2012
1112012
Interactions among P450 enzymes when combined in reconstituted systems: formation of a 2B4− 1A2 complex with a high affinity for NADPH− cytochrome P450 reductase
WL Backes, CJ Batie, GF Cawley
Biochemistry 37 (37), 12852-12859, 1998
1001998
Substrate-dependent competition of different P 450 isoenzymes for limiting NADPH-cytochrome P 450 reductase
GF Cawley, CJ Batie, WL Backes
Biochemistry 34 (4), 1244-1247, 1995
891995
Cytochrome P-450 LM2 reduction: substrate effects on the rate of reductase-LM2 association
WL Backes, CS Eyer
Journal of Biological Chemistry 264 (11), 6252-6259, 1989
801989
Ethylbenzene induces microsomal oxygen free radical generation: antibody-directed characterization of the responsible cytochrome P450 enzymes
SC Serron, N Dwivedi, WL Backes
Toxicology and applied pharmacology 164 (3), 305-311, 2000
752000
Evidence supporting the interaction of CYP2B4 and CYP1A2 in microsomal preparations
GF Cawley, S Zhang, RW Kelley, WL Backes
Drug metabolism and disposition 29 (12), 1529-1534, 2001
652001
Particulate matter containing environmentally persistent free radicals induces AhR-dependent cytokine and reactive oxygen species production in human bronchial epithelial cells
AC Harmon, VY Hebert, SA Cormier, B Subramanian, JR Reed, ...
PloS one 13 (10), e0205412, 2018
632018
Effects of ionic strength on the functional interactions between CYP2B4 and CYP1A2
RW Kelley, JR Reed, WL Backes
Biochemistry 44 (7), 2632-2641, 2005
562005
Reduction kinetics of purified rat liver cytochrome P-450. Evidence for a sequential reaction mechanism dependent on the hemoprotein spin state
PP Tamburini, GG Gibson, WL Backes, SG Sligar, JB Schenkman
Biochemistry 23 (20), 4526-4533, 1984
561984
Cytochrome P450 system proteins reside in different regions of the endoplasmic reticulum
JW Park, JR Reed, LM Brignac-Huber, WL Backes
Biochemical Journal 464 (2), 241-249, 2014
552014
Kinetics of hepatic cytochrome P-450 reduction: correlation with spin state of the ferric heme
WL Backes, SG Sligar, JB Schenkman
Biochemistry 21 (6), 1324-1330, 1982
551982
Cytochrome P450 organization and function are modulated by endoplasmic reticulum phospholipid heterogeneity
LM Brignac-Huber, JW Park, JR Reed, WL Backes
Drug Metabolism and Disposition 44 (12), 1859-1866, 2016
542016
The role of protein-protein and protein-membrane interactions on P450 function
EE Scott, CR Wolf, M Otyepka, SC Humphreys, JR Reed, CJ Henderson, ...
Drug metabolism and disposition 44 (4), 576-590, 2016
522016
Relationship between the rate of reductase-cytochrome P450 complex formation and the rate of first electron transfer
CS Eyer, WL Backes
Archives of biochemistry and biophysics 293 (2), 231-240, 1992
521992
Inhibition of cytochrome P450 1A2-mediated metabolism and production of reactive oxygen species by heme oxygenase-1 in rat liver microsomes
J R Reed, G F Cawley, W L Backes
Drug metabolism letters 5 (1), 6-16, 2011
502011
Kinetics of cytochrome P-450 reduction: evidence for faster reduction of the high-spin ferric state
WL Backes, PP Tamburini, I Jansson, GG Gibson, SG Sligar, ...
Biochemistry 24 (19), 5130-5136, 1985
491985
Heteromeric complex formation between CYP2E1 and CYP1A2: evidence for the involvement of electrostatic interactions
RW Kelley, D Cheng, WL Backes
Biochemistry 45 (51), 15807-15816, 2006
482006
Functional interactions between cytochromes P450 1A2 and 2B4 require both enzymes to reside in the same phospholipid vesicle: evidence for physical complex formation
JR Reed, M Eyer, WL Backes
Journal of biological chemistry 285 (12), 8942-8952, 2010
472010
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Artículos 1–20