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charles skarbek
charles skarbek
INSERM- Université de Paris
Dirección de correo verificada de inserm.fr
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Anticancer boron-containing prodrugs responsive to oxidative stress from the tumor microenvironment
H Maslah, C Skarbek, S Pethe, R Labruère
European Journal of Medicinal Chemistry 207, 112670, 2020
482020
Prodrugs as drug delivery system in oncology
J Delahousse, C Skarbek, A Paci
Cancer Chemotherapy and Pharmacology 84, 937-958, 2019
312019
Arylboronate prodrugs of doxorubicin as promising chemotherapy for pancreatic cancer
C Skarbek, S Serra, H Maslah, E Rascol, R Labruère
Bioorganic chemistry 91, 103158, 2019
282019
Preactivated oxazaphosphorines designed for isophosphoramide mustard delivery as bulk form or nanoassemblies: synthesis and proof of concept
C Skarbek, LL Lesueur, H Chapuis, A Deroussent, C Pioche− Durieu, ...
Journal of medicinal chemistry 58 (2), 705-717, 2015
222015
In‐Cell Generation of Anticancer Phenanthridine Through Bioorthogonal Cyclization in Antitumor Prodrug Development
H Maslah, C Skarbek, C Gourson, MA Plamont, S Pethe, L Jullien, ...
Angewandte Chemie International Edition 60 (45), 24043-24047, 2021
122021
Photodegradation of methotrexate in aqueous solution: degradation kinetics and identification of transformation products
A Espinosa, S Nélieu, P Lieben, C Skarbek, R Labruère, P Benoit
Environmental Science and Pollution Research 29 (4), 6060-6071, 2022
72022
Structural modification and biological activity studies of tagitinin C and its derivatives
TH Au, C Skarbek, S Pethe, R Labruere, JP Baltaze, TPH Nguyen, ...
Tetrahedron 92, 132248, 2021
52021
Simultaneous quantification of preactivated ifosfamide derivatives and of 4-hydroxyifosfamide by high performance liquid chromatography–tandem mass spectrometry in mouse plasma …
A Deroussent, C Skarbek, A Maury, H Chapuis, E Daudigeos-Dubus, ...
Journal of Chromatography B 992, 30-35, 2015
52015
Re-designing environmentally persistent pharmaceutical pollutant through programmed inactivation: The case of methotrexate
A Espinosa, E Rascol, MA Flos, C Skarbek, P Lieben, E Bannerman, ...
Chemosphere 306, 135616, 2022
42022
Poly-isoprenylated ifosfamide analogs: preactivated antitumor agents as free formulation or nanoassemblies
C Skarbek, J Delahousse, C Pioche-Durieu, S Baconnais, A Deroussent, ...
International journal of pharmaceutics 532 (2), 748-756, 2017
42017
Oxazaphosphorines combined with immune checkpoint blockers: dose-dependent tuning between immune and cytotoxic effects
J Delahousse, C Skarbek, M Desbois, JL Perfettini, N Chaput, A Paci
Journal for Immunotherapy of Cancer 8 (2), 2020
32020
Enhanced activity of pre-activated oxazaphosphorine prodrugs designed for drug delivery strategy: influence of the length of the engrafted group.
C Skarbek, H Chapuis, L Lesueur, M Rivard, T Martens, D Desmaele, ...
Cancer Research 73 (8_Supplement), 5671-5671, 2013
32013
Development of a clot-adhesive coating to improve the performance of thrombectomy devices
C Skarbek, V Anagnostakou, E Procopio, M Epshtein, CM Raskett, ...
Journal of NeuroInterventional Surgery 15 (12), 1207-1211, 2023
2023
Synthesis of 6-methylphenanthridines and evaluation against human papillomavirus-related endocervical adenocarcinoma (KB 3.1) cells
H Maslah, C Skarbek, R Labruère
Phytochemistry Letters 54, 146-152, 2023
2023
Molecular Imaging of Experimental Abdominal Aortic Aneurysms Targeting Vascular Homeostasis Disruption via CD31 Shedding
JN Sénémaud, C Skarbek, J Vigne, F Rouzet, Y Castier, G Caligiuri
European Journal of Vascular and Endovascular Surgery 64 (6), 735-736, 2022
2022
Between the Devil and the Deep Blue Sea: New Insights into the Effects of Cancer Therapy on Abdominal Aortic Aneurysm Growth
J Sénémaud, C Skarbek
European Journal of Vascular and Endovascular Surgery 64 (2), 265, 2022
2022
Derivatives of oxazaphosphorines and therapeutic uses thereof
A Paci, T Martens, M Rivard, D Desmaele, C Skarbek, P Couvreur
US Patent 10,098,901, 2018
2018
Synthèse et évaluation pharmacologique d’analogues préactivés de l’ifosfamide: prodrogues et nanoparticules à visée antitumorale
C Skarbek
Université Paris Saclay (COmUE), 2017
2017
Combined strategy based on pre-activated analogs of oxazaphosphorines for increased therapeutic index and immune modulation
J Delahousse, C Skarbek, V Gauthier, M Desbois, E Roger, ...
Cancer Research 77 (13_Supplement), 2195-2195, 2017
2017
New oxazaphosphorine prodrugs for immunotherapy and nanomedicine against cancer
C Skarbek, H Gonde, M Desbois, J Delahousse, N Chaput-Gras, ...
Cancer Research 76 (14_Supplement), 2194-2194, 2016
2016
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