| Cold adapted enzymes. AO Smalås, HK Leiros, V Os, NP Willassen Biotechnology annual review 6, 1-57, 2000 | 275 | 2000 |
| Specific radiation damage can be used to solve macromolecular crystal structures RBG Ravelli, HKS Leiros, B Pan, M Caffrey, S McSweeney Structure 11 (2), 217-224, 2003 | 183 | 2003 |
| Trypsin specificity as elucidated by LIE calculations, X‐ray structures, and association constant measurements HKS Leiros, BO Brandsdal, OA Andersen, V Os, I Leiros, R Helland, ... Protein science 13 (4), 1056-1070, 2004 | 129 | 2004 |
| Structural comparison of psychrophilic and mesophilic trypsins: Elucidating the molecular basis of cold‐adaptation HK Schrøder Leiros, NP Willassen, AO Smalås European Journal of Biochemistry 267 (4), 1039-1049, 2000 | 120 | 2000 |
| Synthetic cationic antimicrobial peptides bind with their hydrophobic parts to drug site II of human serum albumin A Sivertsen, J Isaksson, HKS Leiros, J Svenson, JS Svendsen, ... BMC Structural Biology 14, 1-14, 2014 | 118 | 2014 |
| Structural and functional properties of isocitrate dehydrogenase from the psychrophilic bacterium Desulfotalea psychrophila reveal a cold-active enzyme with an unusual high … AE Fedøy, N Yang, A Martinez, HKS Leiros, IH Steen Journal of molecular biology 372 (1), 130-149, 2007 | 103 | 2007 |
| The structure of bovine lysosomal α-mannosidase suggests a novel mechanism for low-pH activation P Heikinheimo, R Helland, HKS Leiros, I Leiros, S Karlsen, G Evjen, ... Journal of molecular biology 327 (3), 631-644, 2003 | 102 | 2003 |
| Structural basis of 5-nitroimidazole antibiotic resistance: the crystal structure of NimA from Deinococcus radiodurans HKS Leiros, S Kozielski-Stuhrmann, U Kapp, L Terradot, GA Leonard, ... Journal of Biological Chemistry 279 (53), 55840-55849, 2004 | 96 | 2004 |
| Atomic resolution structures of trypsin provide insight into structural radiation damage HKS Leiros, SM McSweeney, AO Smalås Acta Crystallographica Section D: Biological Crystallography 57 (4), 488-497, 2001 | 90 | 2001 |
| Functional and structural studies of a novel cold-adapted esterase from an Arctic intertidal metagenomic library J Fu, HKS Leiros, D de Pascale, KA Johnson, HM Blencke, B Landfald Applied microbiology and biotechnology 97, 3965-3978, 2013 | 89 | 2013 |
| Structure of phenylalanine hydroxylase from Colwellia psychrerythraea 34H, a monomeric cold active enzyme with local flexibility around the active site and high overall stability HKS Leiros, AL Pey, M Innselset, E Moe, I Leiros, IH Steen, A Martinez Journal of Biological Chemistry 282 (30), 21973-21986, 2007 | 84 | 2007 |
| Crystal structure of alkaline phosphatase from the Antarctic bacterium TAB5 E Wang, D Koutsioulis, HKS Leiros, OA Andersen, V Bouriotis, E Hough, ... Journal of molecular biology 366 (4), 1318-1331, 2007 | 80 | 2007 |
| Is radiation damage dependent on the dose rate used during macromolecular crystallography data collection? HKS Leiros, J Timmins, RBG Ravelli, SM McSweeney Acta Crystallographica Section D: Biological Crystallography 62 (2), 125-132, 2006 | 74 | 2006 |
| Discovery of novel inhibitor scaffolds against the metallo-β-lactamase VIM-2 by surface plasmon resonance (SPR) based fragment screening T Christopeit, TJO Carlsen, R Helland, HKS Leiros Journal of Medicinal Chemistry 58 (21), 8671-8682, 2015 | 72 | 2015 |
| Metallo-β-lactamase inhibitors by bioisosteric replacement: Preparation, activity and binding S Skagseth, S Akhter, MH Paulsen, Z Muhammad, S Lauksund, ... European journal of medicinal chemistry 135, 159-173, 2017 | 68 | 2017 |
| Crystal structure of the mobile metallo-β-lactamase AIM-1 from Pseudomonas aeruginosa: insights into antibiotic binding and the role of Gln157 HKS Leiros, PS Borra, BO Brandsdal, KSW Edvardsen, J Spencer, ... Antimicrobial agents and chemotherapy 56 (8), 4341-4353, 2012 | 66 | 2012 |
| Residue determinants and sequence analysis of cold-adapted trypsins HK Schrøder Leiros, NP Willassen, AO Smalås Extremophiles 3, 205-219, 1999 | 66 | 1999 |
| OXA-48-mediated ceftazidime-avibactam resistance is associated with evolutionary trade-offs C Fröhlich, V Sørum, AM Thomassen, PJ Johnsen, HKS Leiros, ... Msphere 4 (2), 10.1128/msphere. 00024-19, 2019 | 58 | 2019 |
| Electrostatics of mesophilic and psychrophilic trypsin isoenzymes: qualitative evaluation of electrostatic differences at the substrate binding site AA Gorfe, BO Brandsdal, HKS Leiros, R Helland, AO Smalås Proteins: Structure, Function, and Bioinformatics 40 (2), 207-217, 2000 | 57 | 2000 |
| Discovery of a novel covalent non-β-lactam inhibitor of the metallo-β-lactamase NDM-1 T Christopeit, A Albert, HKS Leiros Bioorganic & medicinal chemistry 24 (13), 2947-2953, 2016 | 55 | 2016 |
Nils Peder WillassenUiT The Arctic University of NorwayDirección de correo verificada de uit.no
