Both p62/SQSTM1-HDAC6-dependent autophagy and the aggresome pathway mediate CDK1 degradation in human breast cancer M Galindo-Moreno, S Giráldez, C Sáez, MÁ Japón, M Tortolero, F Romero Scientific reports 7 (1), 10078, 2017 | 43 | 2017 |
Loss of FBXW7 and accumulation of MCL1 and PLK1 promote paclitaxel resistance in breast cancer J Gasca, ML Flores, S Giráldez, M Ruiz-Borrego, M Tortolero, F Romero, ... Oncotarget 7 (33), 52751, 2016 | 33 | 2016 |
SCFFBXW7α modulates the intra-S-phase DNA-damage checkpoint by regulating Polo like kinase-1 stability S Giráldez, J Herrero-Ruiz, M Mora-Santos, MÁ Japón, M Tortolero, ... Oncotarget 5 (12), 4370, 2014 | 28 | 2014 |
βTrCP controls the lysosome-mediated degradation of CDK1, whose accumulation correlates with tumor malignancy J Herrero-Ruiz, M Mora-Santos, S Giráldez, C Sáez, MÁ Japón, ... Oncotarget 5 (17), 7563, 2014 | 26 | 2014 |
G1/S phase progression is regulated by PLK1 degradation through the CDK1/βTrCP axis S Giráldez, M Galindo‐Moreno, MC Limón‐Mortés, AC Rivas, ... The FASEB Journal 31 (7), 2925-2936, 2017 | 25 | 2017 |
A single mutation in Securin induces chromosomal instability and enhances cell invasion M Mora-Santos, C Castilla, J Herrero-Ruiz, S Giráldez, MC Limón-Mortés, ... European Journal of Cancer 49 (2), 500-510, 2013 | 25 | 2013 |
SCF (FBXW7)-mediated degradation of p53 promotes cell recovery after UV-induced DNA damage M Galindo-Moreno, S Giráldez, MC Limón-Mortés, A Belmonte-Fernández, ... The FASEB Journal 33 (10), 11420, 2019 | 24 | 2019 |
Breast cancer cell line MCF7 escapes from G1/S arrest induced by proteasome inhibition through a GSK-3β dependent mechanism E Gavilán, S Giráldez, I Sánchez-Aguayo, F Romero, D Ruano, P Daza Scientific Reports 5 (1), 10027, 2015 | 24 | 2015 |
YAP1 regulates the self-organized fate patterning of hESC-derived gastruloids E Stronati, S Giraldez, L Huang, E Abraham, GR McGuire, HT Hsu, ... Stem cell reports 17 (2), 211-220, 2022 | 23 | 2022 |
Glycogen synthase kinase-3β (GSK3β) negatively regulates PTTG1/human securin protein stability, and GSK3β inactivation correlates with securin accumulation in breast tumors M Mora-Santos, MC Limón-Mortés, S Giráldez, J Herrero-Ruiz, C Sáez, ... Journal of Biological Chemistry 286 (34), 30047-30056, 2011 | 23 | 2011 |
p53 and FBXW7: sometimes two guardians are worse than one M Galindo-Moreno, S Giráldez, MC Limón-Mortés, A Belmonte-Fernández, ... Cancers 12 (4), 985, 2020 | 11 | 2020 |
Cyclin E overexpression in human mammary epithelial cells promotes epithelial cancer-specific copy number alterations S Giraldez, P Tamayo, N Wineinger, W Kim, SI Reed Iscience 19, 850-859, 2019 | 7 | 2019 |
YAP1 Regulates the Self-organized Fate Patterning of hESCs-Derived Gastruloids S Giraldez, E Stronati, L Huang, HT Hsu, E Abraham, KA Jones, C Estaras bioRxiv, 2021.03. 12.434631, 2021 | 2 | 2021 |
Role of SCF (FBXW7) on cell proliferation recovery after UV treatment M Galindo-Moreno, S Giraldez, MC Limon-Mortes, E Crespo-Martin, ... FEBS OPEN BIO 8, 317-317, 2018 | | 2018 |
HSP90 regulates the G1/S transition and cell cycle progression in a PLK1-dependent manner M Galindo Moreno, S Giraldez, MC Limon-Mortes, J Herrero-Ruiz, ... FEBS JOURNAL 284, 298-298, 2017 | | 2017 |
Loss of FBXW7 and accumulation of MCL1 and PLK1 promote paclitaxel resistance in breast cancer J Gasca Bellido, ML Flores, S Giráldez, M Ruiz-Borrego, M Tortolero, ... Impact Journals, 2016 | | 2016 |
Breast cancer cell line MCF7 escapes from G1/S arrest induced by proteasome inhibition through a GSK-3 beta dependent mechanism P Daza, E Gavilan, S Giraldez, I Sanchez-Aguayo, F Romero, D Ruano FEBS JOURNAL 282, 159-159, 2015 | | 2015 |
Influencia de FBWX7 en la adquisición de resistencia a paclitaxel en cáncer de mama J Gasca Bellido, R Ávila Polo, ML Flores, S Giráldez, M Tortolero, ... | | 2014 |
Regulación de los niveles de PLK1 por la E3 ligasa SKP1-CUL1-F-box AC Rivas, S Giráldez, J Herrero-Ruiz, M Mora-Santos, MC Limón-Mortés, ... | | 2014 |
SCF-FBW7 alpha targets polo-like kinase 1 for degradation in a cell cycle-dependent manner S Giraldez, J Herrero-Ruiz, M Mora-Santos, MC Limon-Mortes, MA Japon, ... FEBS JOURNAL 279, 176-176, 2012 | | 2012 |