| Reduced diversity of faecal microbiota in Crohn’s disease revealed by a metagenomic approach C Manichanh, L Rigottier-Gois, E Bonnaud, K Gloux, E Pelletier, ... Gut 55 (2), 205-211, 2006 | 2675 | 2006 |
| Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp. J RoCA, R Ishida, JM Berger, T Andoh, JC Wang Proceedings of the National Academy of Sciences 91 (5), 1781-1785, 1994 | 436 | 1994 |
| The capture of a DNA double helix by an ATP-dependent protein clamp: a key step in DNA transport by type II DNA topoisomerases J Roca, JC Wang Cell 71 (5), 833-840, 1992 | 430 | 1992 |
| DNA transport by a type II DNA topoisomerase: evidence in favor of a two-gate mechanism J Roca, JC Wang Cell 77 (4), 609-616, 1994 | 383 | 1994 |
| Knotting probability of DNA molecules confined in restricted volumes: DNA knotting in phage capsids J Arsuaga, M Vázquez, S Trigueros, DW Sumners, J Roca Proceedings of the National Academy of Sciences 99 (8), 5373-5377, 2002 | 313 | 2002 |
| The mechanisms of DNA topoisomerases J Roca Trends in biochemical sciences 20 (4), 156-160, 1995 | 304 | 1995 |
| Storage conditions of intestinal microbiota matter in metagenomic analysis S Cardona, A Eck, M Cassellas, M Gallart, C Alastrue, J Dore, F Azpiroz, ... BMC microbiology 12, 1-8, 2012 | 285 | 2012 |
| DNA knots reveal a chiral organization of DNA in phage capsids J Arsuaga, M Vazquez, P McGuirk, S Trigueros, DW Sumners, J Roca Proceedings of the National Academy of Sciences 102 (26), 9165-9169, 2005 | 283 | 2005 |
| DNA transport by a type II topoisomerase: direct evidence for a two-gate mechanism. J Roca, JM Berger, SC Harrison, JC Wang Proceedings of the National Academy of Sciences 93 (9), 4057-4062, 1996 | 256 | 1996 |
| Anal gas evacuation and colonic microbiota in patients with flatulence: effect of diet C Manichanh, A Eck, E Varela, J Roca, JC Clemente, A González, ... Gut 63 (3), 401-408, 2014 | 157 | 2014 |
| Fractal dimension and localization of DNA knots E Ercolini, F Valle, J Adamcik, G Witz, R Metzler, P De Los Rios, J Roca, ... Physical review letters 98 (5), 058102, 2007 | 139 | 2007 |
| Topoisomerase II, not topoisomerase I, is the proficient relaxase of nucleosomal DNA J Salceda, X Fernández, J Roca The EMBO journal 25 (11), 2575-2583, 2006 | 133 | 2006 |
| On the simultaneous binding of eukaryotic DNA topoisomerase II to a pair of double-stranded DNA helices J Roca, JM Berger, JC Wang Journal of Biological chemistry 268 (19), 14250-14255, 1993 | 128 | 1993 |
| Topoisomerase II: a fitted mechanism for the chromatin landscape J Roca Nucleic acids research 37 (3), 721-730, 2009 | 103 | 2009 |
| Topoisomerase II is required for the production of long Pol II gene transcripts in yeast RS Joshi, B Pina, J Roca Nucleic acids research 40 (16), 7907-7915, 2012 | 98 | 2012 |
| DNA topoisomerase II activity in nonreplicating, transcriptionally inactive, chicken late spermatids. J Roca, C Mezquita The EMBO Journal 8 (6), 1855-1860, 1989 | 93 | 1989 |
| Novel display of knotted DNA molecules by two-dimensional gel electrophoresis S Trigueros, J Arsuaga, ME Vazquez, DW Sumners, J Roca Nucleic acids research 29 (13), e67-e67, 2001 | 90 | 2001 |
| A method for genome-wide analysis of DNA helical tension by means of psoralen–DNA photobinding I Bermúdez, J García-Martínez, JE Pérez-Ortín, J Roca Nucleic acids research 38 (19), e182-e182, 2010 | 74 | 2010 |
| Asymmetric removal of supercoils suggests how topoisomerase II simplifies DNA topology S Trigueros, J Salceda, I Bermúdez, X Fernández, J Roca Journal of molecular biology 335 (3), 723-731, 2004 | 72 | 2004 |
| The probabilities of supercoil removal and decatenation by yeast DNA topoisomerase II J Roca, JC Wang Genes to Cells 1 (1), 17-27, 1996 | 68 | 1996 |
Manichanh ChaysavanhGroup leader, Vall d'Hebron Research Institute, Barcelona, SpainVerified email at vhir.org
