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Sharon Greenblum
Sharon Greenblum
Research Scientist, Joint Genome Institute
Dirección de correo verificada de lbl.gov
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Metagenomic systems biology of the human gut microbiome reveals topological shifts associated with obesity and inflammatory bowel disease
S Greenblum, PJ Turnbaugh, E Borenstein
Proceedings of the National Academy of Sciences 109 (2), 594-599, 2012
8812012
Extensive strain-level copy-number variation across human gut microbiome species
S Greenblum, R Carr, E Borenstein
Cell 160 (4), 583-594, 2015
2552015
Genetic variations at loci involved in the immune response are risk factors for hepatocellular carcinoma
RJ Clifford, J Zhang, DM Meerzaman, MS Lyu, Y Hu, CM Cultraro, ...
Hepatology 52 (6), 2034-2043, 2010
1492010
Microbiome composition shapes rapid genomic adaptation of Drosophila melanogaster
SM Rudman, SI Greenblum, RC Hughes, S Rajpurohit, O Kiratli, ...
PNAS, 2019
1162019
Direct observation of adaptive tracking on ecological time scales in Drosophila
SM Rudman*, SI Greenblum*, S Rajpurohit*, NJ Betancourt, J Hanna, ...
Science 375 (6586), eabj7484, 2022
1002022
Towards a predictive systems-level model of the human microbiome: progress, challenges, and opportunities
S Greenblum, HC Chiu, R Levy, R Carr, E Borenstein
Current opinion in biotechnology 24 (4), 810-820, 2013
722013
The PathOlogist: an automated tool for pathway-centric analysis
SI Greenblum, S Efroni, CF Schaefer, KH Buetow
BMC bioinformatics 12, 1-10, 2011
522011
Accurate allele frequencies from ultra-low coverage pool-seq samples in evolve-and-resequence experiments
S Tilk, A Bergland, A Goodman, P Schmidt, D Petrov, S Greenblum
G3: Genes, Genomes, Genetics 9 (12), 4159-4168, 2019
312019
Virtual colonoscopy via wavelets
RM Summers, J Li, S Greenblum
US Patent 8,023,710, 2011
272011
Detecting cancer gene networks characterized by recurrent genomic alterations in a population
S Efroni, R Ben-Hamo, M Edmonson, S Greenblum, CF Schaefer, ...
PLoS One 6 (1), e14437, 2011
252011
Systems analysis utilising pathway interactions identifies sonic hedgehog pathway as a primary biomarker and oncogenic target in hepatocellular carcinoma
S Efroni, D Meerzaman, CF Schaefer, S Greenblum, M Soo‐Lyu, Y Hu, ...
IET Systems Biology 7 (6), 243-251, 2013
112013
The Cancer Genome Workbench: identifying and visualizing complex genetic alterations in tumors
J Zhang, R Finney, M Edmonson, C Schaefer, W Rowe, C Yan, R Clifford, ...
NCI Nature Pathway Interaction Database 10, 2010
52010
Automated Image Analysis of Noisy Microarrays
S Greenblum, M Krucoff, J Furst, D Raicu
International Conference on Computer Vision Theory and Applications 2, 371-375, 2007
22007
Wavelet analysis in virtual colonoscopy
S Greenblum, J Li, A Huang, RM Summers
Medical Imaging 2006: Physiology, Function, and Structure from Medical …, 2006
12006
Metagenomic systems biology: frameworks for modeling and characterizing the gut microbiome
SI Greenblum
2014
Genomic taxonomy of anti-cancer drug activity: Profiling of doxorubicin-induced gene expression changes in the NCI-60 cancer cell line panel.
A Monks, C Hose, J Zhang, X Wu, S Greenblum, Y Hu, R Clifford, J Collins, ...
CANCER RESEARCH 69, 2009
2009
Doxorubicin induces activation of p53 pathway in sensitive NCI-60 cell lines that have the composite genotype of wild-type p53and mutant p16
J Zhang, S Greenblum, R Clifford, Y Hu, A Monks, C Hose, J Collins, X Wu, ...
CANCER RESEARCH 69, 2009
2009
Abstract# 2426: Genomic taxonomy of anti-cancer drug activity: Profiling of doxorubicin-induced gene expression changes in the NCI-60 cancer cell line panel.
A Monks, C Hose, J Zhang, X Wu, S Greenblum, Y Hu, R Clifford, J Collins, ...
Cancer Research 69 (9_Supplement), 2426-2426, 2009
2009
Abstract# 2424: Doxorubicin induces activation of p53 pathway in sensitive NCI-60 cell lines that have the composite genotype of wild-type p53 and mutant p16
J Zhang, S Greenblum, R Clifford, Y Hu, A Monks, C Hose, J Collins, X Wu, ...
Cancer Research 69 (9_Supplement), 2424-2424, 2009
2009
Wavelet analysis in virtual colonoscopy [6143-115]
S Greenblum, J Li, A Huang, RM Summers
PROCEEDINGS-SPIE THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING 6143 (2 …, 2006
2006
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Artículos 1–20