Three-dimensional structure of the bacterial cell wall peptidoglycan SO Meroueh, KZ Bencze, D Hesek, M Lee, JF Fisher, TL Stemmler, ... Proceedings of the National Academy of Sciences 103 (12), 4404-4409, 2006 | 530 | 2006 |
How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function LH Otero, A Rojas-Altuve, LI Llarrull, C Carrasco-López, M Kumarasiri, ... Proceedings of the National Academy of Sciences 110 (42), 16808-16813, 2013 | 294 | 2013 |
Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane JS Park, WC Lee, KJ Yeo, KS Ryu, M Kumarasiri, D Hesek, M Lee, ... The FASEB Journal 26 (1), 219, 2012 | 213 | 2012 |
Co-opting the Cell Wall in Fighting Methicillin-Resistant Staphylococcus aureus: Potent Inhibition of PBP 2a by Two Anti-MRSA β-Lactam Antibiotics A Villegas-Estrada, M Lee, D Hesek, SB Vakulenko, S Mobashery Journal of the American Chemical Society 130 (29), 9212-9213, 2008 | 139 | 2008 |
Inhibition of MMP-9 by a selective gelatinase inhibitor protects neurovasculature from embolic focal cerebral ischemia J Cui, S Chen, C Zhang, F Meng, W Wu, R Hu, O Hadass, T Lehmidi, ... Molecular neurodegeneration 7 (1), 1-15, 2012 | 128 | 2012 |
Synthesis and Evaluation of 1,2,4-Triazolo[1,5-a]pyrimidines as Antibacterial Agents Against Enterococcus faecium H Wang, M Lee, Z Peng, B Blázquez, E Lastochkin, M Kumarasiri, ... Journal of medicinal chemistry 58 (10), 4194-4203, 2015 | 116 | 2015 |
Extracellular proteases as targets for treatment of cancer metastases M Lee, R Fridman, S Mobashery Chemical Society Reviews 33 (7), 401-409, 2004 | 109 | 2004 |
Activation for Catalysis of Penicillin-Binding Protein 2a from Methicillin-Resistant Staphylococcus aureus by Bacterial Cell Wall C Fuda, D Hesek, M Lee, K Morio, T Nowak, S Mobashery Journal of the American Chemical Society 127 (7), 2056-2057, 2005 | 105 | 2005 |
Reactions of All Escherichia coli Lytic Transglycosylases with Bacterial Cell Wall M Lee, D Hesek, LI Llarrull, E Lastochkin, H Pi, B Boggess, S Mobashery Journal of the American Chemical Society 135 (9), 3311-3314, 2013 | 104 | 2013 |
Validation of matrix metalloproteinase-9 (MMP-9) as a novel target for treatment of diabetic foot ulcers in humans and discovery of a potent and selective small-molecule MMP-9 … TT Nguyen, D Ding, WR Wolter, RL Pérez, MM Champion, ... Journal of medicinal chemistry 61 (19), 8825-8837, 2018 | 103 | 2018 |
Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins S Cho, Q Wang, CP Swaminathan, D Hesek, M Lee, GJ Boons, ... Proceedings of the National Academy of Sciences 104 (21), 8761-8766, 2007 | 98 | 2007 |
Recognition of peptidoglycan and β-lactam antibiotics by the extracellular domain of the Ser/Thr protein kinase StkP from Streptococcus pneumoniae B Maestro, L Novaková, D Hesek, M Lee, E Leyva, S Mobashery, JM Sanz, ... FEBS letters 585 (2), 357-363, 2011 | 97 | 2011 |
A chemical biological strategy to facilitate diabetic wound healing M Gooyit, Z Peng, WR Wolter, H Pi, D Ding, D Hesek, M Lee, B Boggess, ... ACS chemical biology 9 (1), 105-110, 2014 | 90 | 2014 |
Synthetic peptidoglycan motifs for germination of bacterial spores M Lee, D Hesek, IM Shah, AG Oliver, J Dworkin, S Mobashery Chembiochem 11 (18), 2525-2529, 2010 | 89 | 2010 |
Crystal Structures of Penicillin-Binding Protein 6 from Escherichia coli Y Chen, W Zhang, Q Shi, D Hesek, M Lee, S Mobashery, BK Shoichet Journal of the American Chemical Society 131 (40), 14345-14354, 2009 | 83 | 2009 |
Elucidation of the molecular recognition of bacterial cell wall by modular pneumococcal phage endolysin CPL-1 I Perez-Dorado, NE Campillo, B Monterroso, D Hesek, M Lee, JA Paez, ... Journal of Biological Chemistry 282 (34), 24990-24999, 2007 | 83 | 2007 |
Structural and functional insights into peptidoglycan access for the lytic amidase LytA of Streptococcus pneumoniae P Mellroth, T Sandalova, A Kikhney, F Vilaplana, D Hesek, M Lee, ... MBio 5 (1), 10.1128/mbio. 01120-13, 2014 | 82 | 2014 |
Total Synthesis of N-Acetylglucosamine-1,6-anhydro-N-acetylmuramylpentapeptide and Evaluation of Its Turnover by AmpD from Escherichia coli D Hesek, M Lee, W Zhang, BC Noll, S Mobashery Journal of the American Chemical Society 131 (14), 5187-5193, 2009 | 80 | 2009 |
Synthetic peptidoglycan substrates for penicillin-binding protein 5 of Gram-negative bacteria D Hesek, M Suvorov, K Morio, M Lee, S Brown, SB Vakulenko, ... The Journal of organic chemistry 69 (3), 778-784, 2004 | 71 | 2004 |
A Mechanism-Based Inhibitor Targeting the dd-Transpeptidase Activity of Bacterial Penicillin-Binding Proteins M Lee, D Hesek, M Suvorov, W Lee, S Vakulenko, S Mobashery Journal of the American chemical society 125 (52), 16322-16326, 2003 | 70 | 2003 |