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Nicholas William Ashton
Nicholas William Ashton
Dirección de correo verificada de nih.gov
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Human single-stranded DNA binding proteins are essential for maintaining genomic stability
NW Ashton, E Bolderson, L Cubeddu, KJ O’Byrne, DJ Richard
BMC molecular biology 14, 1-20, 2013
1152013
USP7 is a master regulator of genome stability
GJ Valles, I Bezsonova, R Woodgate, NW Ashton
Frontiers in Cell and Developmental Biology 8, 717, 2020
652020
Néstor-Guillermo Progeria Syndrome: a biochemical insight into Barrier-to-Autointegration Factor 1, alanine 12 threonine mutation
N Paquet, JK Box, NW Ashton, A Suraweera, LV Croft, AJ Urquhart, ...
BMC molecular biology 15, 1-11, 2014
522014
hSSB1 (NABP2/OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway
N Paquet, MN Adams, V Leong, NW Ashton, C Touma, R Gamsjaeger, ...
Nucleic acids research 43 (18), 8817-8829, 2015
472015
hSSB1 (NABP2/OBFC2B) is regulated by oxidative stress
N Paquet, MN Adams, NW Ashton, C Touma, R Gamsjaeger, L Cubeddu, ...
Scientific reports 6 (1), 27446, 2016
392016
A structural analysis of DNA binding by hSSB1 (NABP2/OBFC2B) in solution
C Touma, R Kariawasam, AX Gimenez, RE Bernardo, NW Ashton, ...
Nucleic acids research 44 (16), 7963-7973, 2016
292016
hSSB1 phosphorylation is dynamically regulated by DNA-PK and PPP-family protein phosphatases
NW Ashton, N Paquet, SL Shirran, E Bolderson, R Kariawasam, C Touma, ...
DNA repair 54, 30-39, 2017
172017
A data-driven structural model of hSSB1 (NABP2/OBFC2B) self-oligomerization
C Touma, MN Adams, NW Ashton, M Mizzi, S El-Kamand, DJ Richard, ...
Nucleic acids research 45 (14), 8609-8620, 2017
162017
DNA repair pathways and their therapeutic potential in lung cancer
JT Burgess, LV Croft, NC Wallace, SA Stephenson, MN Adams, ...
Lung Cancer Management 3 (2), 159-173, 2014
152014
hSSB1 associates with and promotes stability of the BLM helicase
LV Croft, NW Ashton, N Paquet, E Bolderson, KJ O’Byrne, DJ Richard
BMC Molecular Biology 18, 1-10, 2017
112017
Novel insight into the composition of human single-stranded DNA-binding protein 1 (hSSB1)-containing protein complexes
NW Ashton, D Loo, N Paquet, KJ O’Byrne, DJ Richard
BMC Molecular Biology 17, 1-8, 2016
112016
COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks
A Suraweera, NS Gandhi, S Beard, JT Burgess, LV Croft, E Bolderson, ...
Communications Biology 4 (1), 484, 2021
102021
DNA polymerase ι interacts with both the TRAF-like and UBL1-2 domains of USP7
NW Ashton, GJ Valles, N Jaiswal, I Bezsonova, R Woodgate
Journal of molecular biology 433 (2), 166733, 2021
102021
Ubiquitin and ubiquitin-like proteins are essential regulators of DNA damage bypass
NA Wilkinson, KS Mnuskin, NW Ashton, R Woodgate
Cancers 12 (10), 2848, 2020
52020
Mechanisms of cisplatin resistance: DNA repair and cellular implications
MN Adams, NW Ashton, N Paquet, K O’Byrne, DJ Richard
Advances in drug resistance research, 1-37, 2014
42014
Strand specificity of ribonucleotide excision repair in Escherichia coli
K Łazowski, M Faraz, A Vaisman, NW Ashton, P Jonczyk, IJ Fijalkowska, ...
Nucleic Acids Research 51 (4), 1766-1782, 2023
22023
Human single-stranded DNA protein 1 (hSSB1): a prognostic factor and target for non-small cell lung cancer (NSCLC) treatment
D Boucher, N Ashton, A Suraweera, J Burgess, E Bolderson, M Barr, ...
17th Annual British Thoracic Oncology Group Conference 2019, S17, 2019
22019
A Novel Interaction Between RAD23A/B and Y-family DNA Polymerases
NW Ashton, N Jaiswal, NC Moreno, IV Semenova, AD Dana, MT Latancia, ...
Journal of molecular biology 435 (24), 168353, 2023
2023
Regulatory networks in genome stability pathways
NW Ashton, A Prakash, TN Moiseeva
Frontiers in Genetics 14, 1171136, 2023
2023
Nuclear magnetic resonance spectral data of the USP7 TRAF and UBL1-2 domains in complex with DNA polymerase ι peptides
GJ Valles, NW Ashton, N Jaiswal, R Woodgate, I Bezsonova
Data in Brief 34, 106680, 2021
2021
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