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saskia van der velden
saskia van der velden
phd at Sanquin
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Mitochondrial dysfunction prevents repolarization of inflammatory macrophages
J Van den Bossche, J Baardman, NA Otto, S van der Velden, AE Neele, ...
Cell reports 17 (3), 684-696, 2016
6962016
Distribution of macrophage polarization markers in human atherosclerosis
JL Stöger, MJJ Gijbels, S van der Velden, M Manca, CM van der Loos, ...
Atherosclerosis 225 (2), 461-468, 2012
6962012
A proinflammatory gut microbiota increases systemic inflammation and accelerates atherosclerosis
E Brandsma, NJ Kloosterhuis, M Koster, DC Dekker, MJJ Gijbels, ...
Circulation research 124 (1), 94-100, 2019
2672019
Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions
MA Hoeksema, MJJ Gijbels, J Van den Bossche, S van der Velden, ...
EMBO molecular medicine 6 (9), 1124-1132, 2014
1652014
A defective pentose phosphate pathway reduces inflammatory macrophage responses during hypercholesterolemia
J Baardman, SGS Verberk, KHM Prange, M van Weeghel, ...
Cell reports 25 (8), 2044-2052. e5, 2018
1602018
Epicardium and myocardium separate from a common precursor pool by crosstalk between bone morphogenetic protein–and fibroblast growth factor–signaling pathways
B van Wijk, G van den Berg, R Abu-Issa, P Barnett, S van der Velden, ...
Circulation research 105 (5), 431-441, 2009
1412009
The BMP antagonist follistatin-like 1 is required for skeletal and lung organogenesis
M Sylva, VSW Li, AAA Buffing, JH van Es, M van den Born, ...
PloS one 6 (8), e22616, 2011
1152011
Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques
J Baardman, SGS Verberk, S Van der Velden, MJJ Gijbels, ...
Nature communications 11 (1), 6296, 2020
832020
Nanoparticle-aided characterization of arterial endothelial architecture during atherosclerosis progression and metabolic therapy
TJ Beldman, TS Malinova, E Desclos, AE Grootemaat, ALS Misiak, ...
ACS nano 13 (12), 13759-13774, 2019
812019
IFN-γ priming of macrophages represses a part of the inflammatory program and attenuates neutrophil recruitment
MA Hoeksema, BP Scicluna, M Boshuizen, S Van Der Velden, AE Neele, ...
The Journal of Immunology 194 (8), 3909-3916, 2015
792015
Inhibiting epigenetic enzymes to improve atherogenic macrophage functions
J Van den Bossche, AE Neele, MA Hoeksema, F De Heij, MCS Boshuizen, ...
Biochemical and biophysical research communications 455 (3-4), 396-402, 2014
742014
Interferon-β promotes macrophage foam cell formation by altering both cholesterol influx and efflux mechanisms
MCS Boshuizen, MA Hoeksema, AE Neele, S van der Velden, ...
Cytokine 77, 220-226, 2016
422016
Myeloid Kdm6b deficiency results in advanced atherosclerosis
AE Neele, MJJ Gijbels, S van der Velden, MA Hoeksema, ...
Atherosclerosis 275, 156-165, 2018
262018
LinRegPCR: Analysis of quantitative RT-PCR data [computer program]
J Ruijter, S Van Der Velden, A Ilgun
Amsterdam, Netherlands: Heart Failure Research Center, Academic Medical Centre, 2009
262009
Macrophage Kdm6b controls the pro-fibrotic transcriptome signature of foam cells
AE Neele, KHM Prange, MA Hoeksema, S Van Der Velden, T Lucas, ...
Epigenomics 9 (4), 383-391, 2017
252017
Update on the pathophysiology of transfusion-related acute lung injury
EANZ van der Laan, S van der Velden, L Porcelijn, JW Semple, ...
Current opinion in hematology 27 (6), 386-391, 2020
212020
Helminth antigens counteract a rapid high-fat diet-induced decrease in adipose tissue eosinophils
SM van den Berg, AD van Dam, PJH Kusters, L Beckers, M Den Toom, ...
Journal of molecular endocrinology 59 (3), 245-255, 2017
212017
Targeting histone deacetylases in myeloid cells inhibits their maturation and inflammatory function with limited effects on atherosclerosis
R Luque-Martin, J Van den Bossche, RC Furze, AE Neele, ...
Frontiers in Pharmacology 10, 1242, 2019
192019
MAb therapy against the IFN-α/β receptor subunit 1 stimulates arteriogenesis in a murine hindlimb ischaemia model without enhancing atherosclerotic burden
PFA Teunissen, MC Boshuizen, MR Hollander, PS Biesbroek, ...
Cardiovascular research 107 (2), 255-266, 2015
192015
Circulating CD14+ CD16− classical monocytes do not associate with a vulnerable plaque phenotype, and do not predict secondary events in severe atherosclerotic patients
JAL Meeuwsen, JJ de Vries, A van Duijvenvoorde, S van der Velden, ...
Journal of molecular and cellular cardiology 127, 260-269, 2019
182019
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