| Cutting edge: the phosphoinositide 3-kinase p110δ is critical for the function of CD4+ CD25+ Foxp3+ regulatory T cells DT Patton, OA Garden, WP Pearce, LE Clough, CR Monk, E Leung, ... The Journal of Immunology 177 (10), 6598-6602, 2006 | 367 | 2006 |
| The p110δ isoform of phosphoinositide 3-kinase controls clonal expansion and differentiation of Th cells K Okkenhaug, DT Patton, A Bilancio, F Garçon, WC Rowan, ... The Journal of immunology 177 (8), 5122-5128, 2006 | 250 | 2006 |
| PI3K p110δ regulates T-cell cytokine production during primary and secondary immune responses in mice and humans DR Soond, E Bjørgo, K Moltu, VQ Dale, DT Patton, KM Torgersen, ... Blood, The Journal of the American Society of Hematology 115 (11), 2203-2213, 2010 | 240 | 2010 |
| CD28 provides T-cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 heterodimer F Garçon, DT Patton, JL Emery, E Hirsch, R Rottapel, T Sasaki, ... Blood, The Journal of the American Society of Hematology 111 (3), 1464-1471, 2008 | 174 | 2008 |
| The PI3K p110δ regulates expression of CD38 on regulatory T cells DT Patton, MD Wilson, WC Rowan, DR Soond, K Okkenhaug PloS one 6 (3), e17359, 2011 | 122 | 2011 |
| P-Rex1 and Vav1 cooperate in the regulation of formyl-methionyl-leucyl-phenylalanine–dependent neutrophil responses CD Lawson, S Donald, KE Anderson, DT Patton, HCE Welch The Journal of Immunology 186 (3), 1467-1476, 2011 | 78 | 2011 |
| Ig gene-like molecule CD31 plays a nonredundant role in the regulation of T-cell immunity and tolerance L Ma, C Mauro, GH Cornish, JG Chai, D Coe, H Fu, D Patton, ... Proceedings of the National Academy of Sciences 107 (45), 19461-19466, 2010 | 66 | 2010 |
| Does the PI3K pathway promote or antagonize regulatory T cell development and function? DR Soond, ECM Slack, OA Garden, DT Patton, K Okkenhaug Frontiers in immunology 3, 244, 2012 | 51 | 2012 |
| Pten loss in CD4 T cells enhances their helper function but does not lead to autoimmunity or lymphoma DR Soond, F Garçon, DT Patton, J Rolf, M Turner, C Scudamore, ... The Journal of Immunology 188 (12), 5935-5943, 2012 | 43 | 2012 |
| The PI3K p110δ controls T-cell development, differentiation and regulation DT Patton, F Garcon, K Okkenhaug Biochemical Society Transactions 35 (2), 167-171, 2007 | 41 | 2007 |
| Interleukin-7, but not thymic stromal lymphopoietin, plays a key role in the T cell response to influenza A virus AW Plumb, DT Patton, JH Seo, EK Loveday, F Jean, SF Ziegler, ... PloS one 7 (11), e50199, 2012 | 38 | 2012 |
| The survival and differentiation of pro-B and pre-B cells in the bone marrow is dependent on IL-7Rα Tyr449 DT Patton, AW Plumb, N Abraham The Journal of Immunology 193 (7), 3446-3455, 2014 | 33 | 2014 |
| Loss of phosphatidylinositol 3-kinase activity in regulatory T cells leads to neuronal inflammation AK Stark, E Davenport, DT Patton, CL Scudamore, B Vanhaesebroeck, ... The Journal of Immunology 205 (1), 78-89, 2020 | 24 | 2020 |
| Interleukin‐7 in the transition of bone marrow progenitors to the thymus AW Plumb, A Sheikh, DA Carlow, DT Patton, HJ Ziltener, N Abraham Immunology and Cell Biology 95 (10), 916-924, 2017 | 18 | 2017 |
| Elevated IL-7 availability does not account for T cell proliferation in moderate lymphopenia LC Osborne, DT Patton, JH Seo, N Abraham The Journal of Immunology 186 (4), 1981-1988, 2011 | 15 | 2011 |
| Identification of an HLA‐A* 0201 cytotoxic T lymphocyte epitope specific to the endothelial antigen Tie‐2 JM Ramage, R Metheringham, A Conn, I Spendlove, RS Moss, DT Patton, ... International journal of cancer 110 (2), 245-250, 2004 | 15 | 2004 |
| The development and survival but not function of follicular B cells is dependent on IL-7Rα Tyr449 signaling DT Patton, AW Plumb, SA Redpath, LC Osborne, G Perona-Wright, ... Plos one 9 (2), e88771, 2014 | 10 | 2014 |
| PI3K p110 delta controls the differentiation and function of regulatory T cells DT Patton, JL Emery, WC Rowan, K Okkenhaug Immunology 125, 129-129, 2008 | 2 | 2008 |
| A Novel Bispecific CD8 Treg Modulator Targeting Cytolytic CD8 Regulatory T cells Reduces Pathogenic CD4 T cells and Inflammation in Translational Models of Intestinal … J Gardell, D Boster, J Bowser, C Crane, R Fasnacht, K Fitzpatrick, ... Inflammatory Bowel Diseases 29 (Supplement_1), S12-S12, 2023 | 1 | 2023 |
| Glucocorticoid Synthesis By Mouse Bone Marrow and Spleen MD Taves, AW Plumb, DT Patton, C Ma, N Abraham, KK Soma ENDOCRINE REVIEWS 35 (3), 2014 | 1 | 2014 |
Klaus OkkenhaugDivision of Immunology, Department of Pathology, University of CambridgeVerified email at cam.ac.uk
