Sowmya Iyer
Sowmya Iyer
Computational Biologist, Massachusetts General Hospital
Verified email at mgh.harvard.edu
Title
Cited by
Cited by
Year
Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors
J Wang, J Zhuang, S Iyer, XY Lin, TW Whitfield, MC Greven, BG Pierce, ...
Genome research 22 (9), 1798-1812, 2012
7692012
Factorbook. org: a Wiki-based database for transcription factor-binding data generated by the ENCODE consortium
J Wang, J Zhuang, S Iyer, XY Lin, MC Greven, BH Kim, J Moore, ...
Nucleic acids research 41 (D1), D171-D176, 2012
2712012
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors
J Grünewald, R Zhou, SP Garcia, S Iyer, CA Lareau, MJ Aryee, JK Joung
Nature 569 (7756), 433-437, 2019
1642019
Cancer-specific retargeting of BAF complexes by a prion-like domain
G Boulay, GJ Sandoval, N Riggi, S Iyer, R Buisson, B Naigles, ME Awad, ...
Cell 171 (1), 163-178. e19, 2017
1342017
CRISPR DNA base editors with reduced RNA off-target and self-editing activities
J Grünewald, R Zhou, S Iyer, CA Lareau, SP Garcia, MJ Aryee, JK Joung
Nature biotechnology 37 (9), 1041-1048, 2019
662019
Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing
Q Tang, S Iyer, R Lobbardi, JC Moore, H Chen, C Lareau, C Hebert, ...
Journal of Experimental Medicine 214 (10), 2875-2887, 2017
532017
Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma
MN Hayes, K McCarthy, A Jin, ML Oliveira, S Iyer, SP Garcia, S Sindiri, ...
Cell stem cell 22 (3), 414-427. e6, 2018
292018
OTX2 activity at distal regulatory elements shapes the chromatin landscape of group 3 medulloblastoma
G Boulay, ME Awad, N Riggi, TC Archer, S Iyer, WE Boonseng, ...
Cancer discovery 7 (3), 288-301, 2017
282017
Epigenome editing of microsatellite repeats defines tumor-specific enhancer functions and dependencies
G Boulay, A Volorio, S Iyer, LC Broye, I Stamenkovic, N Riggi, MN Rivera
Genes & development 32 (15-16), 1008-1019, 2018
202018
A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing
J Grünewald, R Zhou, CA Lareau, SP Garcia, S Iyer, BR Miller, ...
Nature Biotechnology, 1-4, 2020
172020
High-throughput sequencing analysis of post-liver transplantation HCV E2 glycoprotein evolution in the presence and absence of neutralizing monoclonal antibody
GJ Babcock, S Iyer, HL Smith, Y Wang, K Rowley, DM Ambrosino, ...
PloS one 9 (6), e100325, 2014
162014
Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia
EG Garcia, S Iyer, SP Garcia, S Loontiens, RI Sadreyev, F Speleman, ...
Leukemia 32 (8), 1860-1865, 2018
132018
The macrophage‐expressed gene (mpeg) 1 identifies a subpopulation of B cells in the adult zebrafish
G Ferrero, E Gomez, S Lyer, M Rovira, M Miserocchi, DM Langenau, ...
Journal of leukocyte biology 107 (3), 431-443, 2020
92020
Molecularly distinct models of zebrafish Myc-induced B cell leukemia
C Borga, CA Foster, S Iyer, SP Garcia, DM Langenau, JK Frazer
Leukemia 33 (2), 559-562, 2019
72019
CRISPR adenine and cytosine base editors with reduced RNA off-target activities
J Grünewald, R Zhou, S Iyer, CA Lareau, SP Garcia, MJ Aryee, JK Joung
bioRxiv, 631721, 2019
72019
A (fire) cloud-based DNA methylation data preprocessing and quality control platform
D Kangeyan, A Dunford, S Iyer, C Stewart, M Hanna, G Getz, MJ Aryee
BMC bioinformatics 20 (1), 160, 2019
32019
77 Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors
J Wang, J Zhuang, S Iyer, X Lin, TW Whitfield, MC Greven, BG Pierce, ...
Journal of Biomolecular Structure and Dynamics 31 (sup1), 49-50, 2013
12013
LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma
T Keskin, A Bakaric, P Waszyk, G Boulay, M Torsello, S Cornaz-Buros, ...
Cell Reports 31 (2), 2020
2020
LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma LIN28B Control of EWS-FLI1 Stability
T Keskin, A Bakaric, P Waszyk, G Boulay, M Torsello, S Cornaz-Buros, ...
Cell Reports 30 (13), 4567-4583. e5, 2020
2020
Novel CRISPR Cytosine Base Editors with Minimized Off-Target Effects and Improved Editing Properties
J Grunewald, R Zhou, SP Garcia, S Iyer, CA Lareau, MJ Aryee, JK Joung
MOLECULAR THERAPY 27 (4), 295-295, 2019
2019
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