Sowmya Iyer
Sowmya Iyer
Senior Scientist Computational Biology, Verve Therapeutics
Verified email at
Cited by
Cited by
Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors
J Wang, J Zhuang, S Iyer, XY Lin, TW Whitfield, MC Greven, BG Pierce, ...
Genome research 22 (9), 1798-1812, 2012
Factorbook. org: a Wiki-based database for transcription factor-binding data generated by the ENCODE consortium
J Wang, J Zhuang, S Iyer, XY Lin, MC Greven, BH Kim, J Moore, ...
Nucleic acids research 41 (D1), D171-D176, 2012
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors
J Grünewald, R Zhou, SP Garcia, S Iyer, CA Lareau, MJ Aryee, JK Joung
Nature 569 (7756), 433-437, 2019
Cancer-specific retargeting of BAF complexes by a prion-like domain
G Boulay, GJ Sandoval, N Riggi, S Iyer, R Buisson, B Naigles, ME Awad, ...
Cell 171 (1), 163-178. e19, 2017
CRISPR DNA base editors with reduced RNA off-target and self-editing activities
J Grünewald, R Zhou, S Iyer, CA Lareau, SP Garcia, MJ Aryee, JK Joung
Nature biotechnology 37 (9), 1041-1048, 2019
Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing
Q Tang, S Iyer, R Lobbardi, JC Moore, H Chen, C Lareau, C Hebert, ...
Journal of Experimental Medicine 214 (10), 2875-2887, 2017
CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells
IC Kurt, R Zhou, S Iyer, SP Garcia, BR Miller, LM Langner, J Grünewald, ...
Nature biotechnology 39 (1), 41-46, 2021
A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing
J Grünewald, R Zhou, CA Lareau, SP Garcia, S Iyer, BR Miller, ...
Nature biotechnology 38 (7), 861-864, 2020
Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma
MN Hayes, K McCarthy, A Jin, ML Oliveira, S Iyer, SP Garcia, S Sindiri, ...
Cell stem cell 22 (3), 414-427. e6, 2018
OTX2 activity at distal regulatory elements shapes the chromatin landscape of group 3 medulloblastoma
G Boulay, ME Awad, N Riggi, TC Archer, S Iyer, WE Boonseng, ...
Cancer discovery 7 (3), 288-301, 2017
Epigenome editing of microsatellite repeats defines tumor-specific enhancer functions and dependencies
G Boulay, A Volorio, S Iyer, LC Broye, I Stamenkovic, N Riggi, MN Rivera
Genes & development 32 (15-16), 1008-1019, 2018
Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer
SE Johnstone, A Reyes, Y Qi, C Adriaens, E Hegazi, K Pelka, JH Chen, ...
Cell 182 (6), 1474-1489. e23, 2020
High-throughput sequencing analysis of post-liver transplantation HCV E2 glycoprotein evolution in the presence and absence of neutralizing monoclonal antibody
GJ Babcock, S Iyer, HL Smith, Y Wang, K Rowley, DM Ambrosino, ...
PloS one 9 (6), e100325, 2014
The macrophage‐expressed gene (mpeg) 1 identifies a subpopulation of B cells in the adult zebrafish
G Ferrero, E Gomez, S Lyer, M Rovira, M Miserocchi, DM Langenau, ...
Journal of leukocyte biology 107 (3), 431-443, 2020
Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia
EG Garcia, S Iyer, SP Garcia, S Loontiens, RI Sadreyev, F Speleman, ...
Leukemia 32 (8), 1860-1865, 2018
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates
K Musunuru, AC Chadwick, T Mizoguchi, SP Garcia, JE DeNizio, ...
Nature 593 (7859), 429-434, 2021
Molecularly distinct models of zebrafish Myc-induced B cell leukemia
C Borga, CA Foster, S Iyer, SP Garcia, DM Langenau, JK Frazer
Leukemia 33 (2), 559-562, 2019
A (fire) cloud-based DNA methylation data preprocessing and quality control platform
D Kangeyan, A Dunford, S Iyer, C Stewart, M Hanna, G Getz, MJ Aryee
BMC bioinformatics 20 (1), 160, 2019
CRISPR adenine and cytosine base editors with reduced RNA off-target activities
J Grünewald, R Zhou, S Iyer, CA Lareau, SP Garcia, MJ Aryee, JK Joung
bioRxiv, 631721, 2019
LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma
T Keskin, A Bakaric, P Waszyk, G Boulay, M Torsello, S Cornaz-Buros, ...
Cell Reports 31 (2), 2020
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