| A huntingtin knockin pig model recapitulates features of selective neurodegeneration in Huntington’s disease S Yan, Z Tu, Z Liu, N Fan, H Yang, S Yang, W Yang, Y Zhao, Z Ouyang, ... Cell 173 (4), 989-1002. e13, 2018 | 328 | 2018 |
| Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9 Y Chen, Y Zheng, Y Kang, W Yang, Y Niu, X Guo, Z Tu, C Si, H Wang, ... Human molecular genetics 24 (13), 3764-3774, 2015 | 291 | 2015 |
| CRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseases Z Tu, W Yang, S Yan, X Guo, XJ Li Molecular neurodegeneration 10 (1), 1-8, 2015 | 138 | 2015 |
| Promoting Cas9 degradation reduces mosaic mutations in non-human primate embryos Z Tu, W Yang, S Yan, A Yin, J Gao, X Liu, Y Zheng, J Zheng, Z Li, S Yang, ... Scientific reports 7 (1), 1-11, 2017 | 135 | 2017 |
| Early Parkinson's disease symptoms in α-synuclein transgenic monkeys Y Niu, X Guo, Y Chen, CE Wang, J Gao, W Yang, Y Kang, W Si, H Wang, ... Human molecular genetics 24 (8), 2308-2317, 2015 | 100 | 2015 |
| Altered neurogenesis and disrupted expression of synaptic proteins in prefrontal cortex of SHANK3-deficient non-human primate H Zhao, Z Tu, H Xu, S Yan, H Yan, Y Zheng, W Yang, J Zheng, Z Li, ... Cell research 27 (10), 1293-1297, 2017 | 84 | 2017 |
| CRISPR/Cas9-mediated PINK1 deletion leads to neurodegeneration in rhesus monkeys W Yang, Y Liu, Z Tu, C Xiao, S Yan, X Ma, X Guo, X Chen, P Yin, Z Yang, ... Cell research 29 (4), 334-336, 2019 | 78 | 2019 |
| Mutant alpha-synuclein causes age-dependent neuropathology in monkey brain W Yang, G Wang, CE Wang, X Guo, P Yin, J Gao, Z Tu, Z Wang, J Wu, ... Journal of Neuroscience 35 (21), 8345-8358, 2015 | 70 | 2015 |
| MANF regulates hypothalamic control of food intake and body weight S Yang, H Yang, R Chang, P Yin, Y Yang, W Yang, S Huang, MA Gaertig, ... Nature communications 8 (1), 1-16, 2017 | 56 | 2017 |
| CRISPR/Cas9: implications for modeling and therapy of neurodegenerative diseases W Yang, Z Tu, Q Sun, XJ Li Frontiers in molecular neuroscience 9, 30, 2016 | 56 | 2016 |
| Truncation of mutant huntingtin in knock-in mice demonstrates exon1 huntingtin is a key pathogenic form H Yang, S Yang, L Jing, L Huang, L Chen, X Zhao, W Yang, Y Pan, P Yin, ... Nature communications 11 (1), 1-15, 2020 | 54 | 2020 |
| A CRISPR monkey model unravels a unique function of PINK1 in primate brains W Yang, S Li, XJ Li Molecular neurodegeneration 14 (1), 1-4, 2019 | 44 | 2019 |
| Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains P Yin, X Guo, W Yang, S Yan, S Yang, T Zhao, Q Sun, Y Liu, S Li, XJ Li Acta neuropathologica 137 (6), 919-937, 2019 | 42 | 2019 |
| PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis W Yang, X Guo, Z Tu, X Chen, R Han, Y Liu, S Yan, Q Wang, Z Wang, ... Protein & cell, 1-21, 2021 | 41 | 2021 |
| Genetically modified large animal models for investigating neurodegenerative diseases W Yang, X Chen, S Li, XJ Li Cell & Bioscience 11 (1), 1-11, 2021 | 26 | 2021 |
| Phosphorylation of myelin regulatory factor by PRKG 2 mediates demyelination in Huntington's disease P Yin, Q Liu, Y Pan, W Yang, S Yang, W Wei, X Chen, Y Hong, D Bai, ... EMBO reports 21 (6), e49783, 2020 | 17 | 2020 |
| Huntingtin-associated protein 1 in mouse hypothalamus stabilizes glucocorticoid receptor in stress response X Chen, N Xin, Y Pan, L Zhu, P Yin, Q Liu, W Yang, X Xu, S Li, XJ Li Frontiers in Cellular Neuroscience 14, 125, 2020 | 17 | 2020 |
| Accumulation of Endogenous Mutant Huntingtin in Astrocytes Exacerbates Neuropathology of Huntington Disease in Mice L Jing, S Cheng, Y Pan, Q Liu, W Yang, S Li, XJ Li Molecular Neurobiology 58 (10), 5112-5126, 2021 | 12 | 2021 |
| CRISPR: Established Editor of Human Embryos? XJ Li, Z Tu, W Yang, S Li Cell stem cell 21 (3), 295-296, 2017 | 8 | 2017 |
| Altered neurogenesis and disrupted expression of synaptic proteins in SHANK3 deficient non-human primate prefrontal cortex H Zhao, Z Tu, H Xu, S Yan, H Yan, Y Zheng, W Yang, J Zheng, Z Li, ... 中国神经科学学会第十二届全国学术会议论文集, 2017 | | 2017 |
Shihua LiJinan UniversityVerified email at jnu.edu.cn
