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Karine Flem-Karlsen
Karine Flem-Karlsen
Verified email at yale.edu
Title
Cited by
Cited by
Year
B7-H3 in cancer–beyond immune regulation
K Flem-Karlsen, Ø Fodstad, M Tan, CE Nunes-Xavier
Trends in cancer 4 (6), 401-404, 2018
1212018
Decreased expression of B7-H3 reduces the glycolytic capacity and sensitizes breast cancer cells to AKT/mTOR inhibitors
CE Nunes-Xavier, KF Karlsen, C Tekle, C Pedersen, T Øyjord, V Hongisto, ...
Oncotarget 7 (6), 6891, 2016
752016
Immunoregulatory protein B7‐H3 promotes growth and decreases sensitivity to therapy in metastatic melanoma cells
K Flem‐Karlsen, C Tekle, Y Andersson, K Flatmark, Ø Fodstad, ...
Pigment cell & melanoma research 30 (5), 467-476, 2017
652017
B7-H3 immune checkpoint protein in human cancer
K Flem-Karlsen, Ø Fodstad, CE Nunes-Xavier
Current medicinal chemistry 27 (24), 4062-4086, 2020
612020
Progress and challenges for the machine learning-based design of fit-for-purpose monoclonal antibodies
R Akbar, H Bashour, P Rawat, PA Robert, E Smorodina, TS Cotet, ...
MAbs 14 (1), 2008790, 2022
592022
Soluble AXL as a marker of disease progression and survival in melanoma
K Flem-Karlsen, M Nyakas, IN Farstad, E McFadden, P Wernhoff, ...
PLoS One 15 (1), e0227187, 2020
312020
p38 MAPK activation through B7-H3-mediated DUSP10 repression promotes chemoresistance
K Flem-Karlsen, C Tekle, T Øyjord, VA Flørenes, GM Mælandsmo, ...
Scientific reports 9 (1), 5839, 2019
292019
Targeting AXL and the DNA damage response pathway as a novel therapeutic strategy in melanoma
K Flem-Karlsen, E McFadden, N Omar, MH Haugen, GF Øy, T Ryder, ...
Molecular cancer therapeutics 19 (3), 895-905, 2020
252020
Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life
A Grevys, R Frick, S Mester, K Flem-Karlsen, J Nilsen, S Foss, KMK Sand, ...
Iscience 25 (2), 2022
242022
Heterogeneous expression and subcellular localization of pyruvate dehydrogenase complex in prostate cancer
CE Nunes-Xavier, J Mingo, M Emaldi, K Flem-Karlsen, GM Mælandsmo, ...
Frontiers in Oncology 12, 873516, 2022
102022
A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma
J Pozniak, D Pedri, E Landeloos, Y Van Herck, A Antoranz, ...
Cell 187 (1), 166-183. e25, 2024
82024
A Three-dimensional ex vivo viability assay reveals a strong correlation between response to targeted inhibitors and mutation status in melanoma lymph node metastases
VA Flørenes, K Flem-Karlsen, E McFadden, IR Bergheim, V Nygaard, ...
Translational Oncology 12 (7), 951-958, 2019
82019
IL-7R licenses a population of epigenetically poised memory CD8+ T cells with superior antitumor efficacy that are critical for melanoma memory
G Micevic, A Daniels, K Flem-Karlsen, K Park, R Talty, M McGeary, ...
Proceedings of the National Academy of Sciences 120 (30), e2304319120, 2023
32023
Oncogenic role of B7-H3 from tumour cell-derived extracellular vesicles
CE Nunes-Xavier, K Flem-Karlsen, Ø Fodstad
Journal of Extracellular Vesicles 7, 127-127, 2018
12018
1025 Tumor-specific CD8+ T cells epigenetically licensed by IL-7R are critical for anti-tumor immunity in melanoma
G Micevic, A Daniels, K Flem-Karlsen, K Park, R Talty, M McGeary, ...
Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023
2023
1234 Immunotherapy induces clonal expansion of cytotoxic tumor-specific TILs in a model of melanoma
G Micevic, A Daniels, K Flem-Karlsen, R Talty, K Park, M Bosenberg, ...
Journal of Investigative Dermatology 143 (5), S212, 2023
2023
Investigating therapeutic candidates and the use of preclinical models to predict treatment response in melanoma
K Flem-Karlsen
Faculty of Medicine, University of Oslo, 2020
2020
Immunoregulatory Protein B7-H3 Promotes Growth and Decreases Tumor Cell Sensitivity to Anti-Cancer Agents
C Nunes-Xavier, K Flem-Karlsen, C Tekle, Ø Fodstad
Annals of Oncology 28, vii12, 2017
2017
Suppressed B7-H3 expression reduces glycolytic capacity and sensitizes tumor cells to anti-cancer agents
CE Nunes-Xavier, K Flem Karlsen, T Øyjord, M Tan, Ø Fodstad
Cancer Research 76 (14_Supplement), 4133-4133, 2016
2016
Antibody Variable Sequences Have a Pronounced Effect on Cellular Uptake, Transport and Plasma Half-Life
A Grevys, R Frick, S Mester, K Flem-Karlsen, J Nilsen, S Foss, KMK Sand, ...
Transport and Plasma Half-Life, 0
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