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Karine Bastard
Karine Bastard
Researcher in Structural Bioinformatics, Genoscope, CEA
Dirección de correo verificada de genoscope.cns.fr
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Revealing the hidden functional diversity of an enzyme family
K Bastard, AAT Smith, C Vergne-Vaxelaire, A Perret, A Zaparucha, ...
Nature chemical biology 10 (1), 42-49, 2014
1302014
Accounting for loop flexibility during protein–protein docking
K Bastard, C Prévost, M Zacharias
Proteins: Structure, Function, and Bioinformatics 62 (4), 956-969, 2006
1092006
A family of native amine dehydrogenases for the asymmetric reductive amination of ketones
O Mayol, K Bastard, L Beloti, A Frese, JP Turkenburg, JL Petit, A Mariage, ...
Nature Catalysis 2 (4), 324-333, 2019
992019
In silico-in vitro screening of protein-protein interactions: towards the next generation of therapeutics
BO Villoutreix, K Bastard, O Sperandio, R Fahraeus, JL Poyet, F Calvo, ...
Current Pharmaceutical Biotechnology 9 (2), 103-122, 2008
892008
Dimorphic motifs in D0 and D1+ D2 domains of killer cell Ig-like receptor 3DL1 combine to form receptors with high, moderate, and no avidity for the complex of a peptide …
D Sharma, K Bastard, LA Guethlein, PJ Norman, N Yawata, M Yawata, ...
The Journal of Immunology 183 (7), 4569-4582, 2009
622009
Docking macromolecules with flexible segments
K Bastard, A Thureau, R Lavery, C Prevost
Journal of computational chemistry 24 (15), 1910-1920, 2003
622003
Identification of subfamily-specific sites based on active sites modeling and clustering
RC de Melo-Minardi, K Bastard, F Artiguenave
Bioinformatics 26 (24), 3075-3082, 2010
502010
Parallel evolution of non-homologous isofunctional enzymes in methionine biosynthesis
K Bastard, A Perret, A Mariage, T Bessonnet, A Pinet-Turpault, JL Petit, ...
Nature Chemical Biology 13 (8), 858-866, 2017
402017
Expanding the reaction space of aldolases using hydroxypyruvate as a nucleophilic substrate
V de Berardinis, C Guérard-Hélaine, E Darii, K Bastard, V Hélaine, ...
Green chemistry 19 (2), 519-526, 2017
282017
Structural studies based on two lysine dioxygenases with distinct regioselectivity brings insights into enzyme specificity within the clavaminate synthase-like family
K Bastard, T Isabet, EA Stura, P Legrand, A Zaparucha
Scientific Reports 8 (1), 16587, 2018
202018
3-Keto-5-aminohexanoate Cleavage Enzyme: A COMMON FOLD FOR AN UNCOMMON CLAISEN-TYPE CONDENSATION*♦
M Bellinzoni, K Bastard, A Perret, A Zaparucha, N Perchat, C Vergne, ...
Journal of Biological Chemistry 286 (31), 27399-27405, 2011
182011
A novel acyl-CoA beta-transaminase characterized from a metagenome
A Perret, C Lechaplais, S Tricot, N Perchat, C Vergne, C Pellé, K Bastard, ...
PLoS One 6 (8), e22918, 2011
182011
The Odyssey of the ancestral Escherich strain through culture collections: an example of allopatric diversification
M Desroches, G Royer, D Roche, M Mercier-Darty, D Vallenet, C Médigue, ...
Msphere 3 (1), 10.1128/msphere. 00553-17, 2018
122018
Accounting for Large Amplitude Protein Deformation during in Silico Macromolecular Docking
K Bastard, A Saladin, C Prévost
International journal of molecular sciences 12 (2), 1316-1333, 2011
92011
On the characterization and selection of diverse conformational ensembles with applications to flexible docking
S Loriot, S Sachdeva, K Bastard, C Prévost, F Cazals
IEEE/ACM Transactions on Computational Biology and Bioinformatics 8 (2), 487-498, 2009
92009
Assemblage flexible de macromolécules: la théorie du champ moyen appliquée au remodelage des boucles protéiques
K Bastard
Paris 7, 2005
22005
NetSyn: genomic context exploration of protein families
M Stam, J Langlois, C Chevalier, G Reboul, K Bastard, C Médigue, ...
bioRxiv, 2023.02. 15.528638, 2023
12023
Diverse Amine dehydrogenases for the biocatalytic synthesis of amines
C Vergne-Vaxelaire, E Elisée, L Ducrot, O Mayol, R Meheust, M Stam, ...
ENZYNOV'2, 2023
2023
Expanding the portfolio of enzymes for biocatalysis by extensive biodiversity screening
C Vergne-Vaxelaire, E Elisée, L Ducrot, R Meheust, M Stam, E Pelletier, ...
6e Symposium International de l'AFERP, 2023
2023
Expanding the portfolio of native Amine Dehydrogenases by extensive biodiversity screening
C Vergne-Vaxelaire, E Elisée, L Ducrot, R Meheust, M Stam, E Pelletier, ...
Amine BioCat 5.0, 2022
2022
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