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Frank B. Sachse
Frank B. Sachse
Director, Cardiovascular Electrophysiology, BioMarin
Dirección de correo verificada de bmrn.com
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Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations
I Splawski, KW Timothy, N Decher, P Kumar, FB Sachse, AH Beggs, ...
Proceedings of the National Academy of Sciences 102 (23), 8089-8096, 2005
7392005
Models of cardiac tissue electrophysiology: progress, challenges and open questions
RH Clayton, O Bernus, EM Cherry, H Dierckx, FH Fenton, L Mirabella, ...
Progress in biophysics and molecular biology 104 (1-3), 22-48, 2011
6802011
De novo KCNQ1 mutation responsible for atrial fibrillation and short QT syndrome in utero
K Hong, DR Piper, A Diaz-Valdecantos, J Brugada, A Oliva, ...
Cardiovascular research 68 (3), 433-440, 2005
3862005
Computational Cardiology: Modeling of Anatomy, Electrophysiology and Mechanics
F Sachse
Springer Berlin/Heidelberg, 2004
3152004
Verification of cardiac tissue electrophysiology simulators using an N-version benchmark
SA Niederer, E Kerfoot, AP Benson, MO Bernabeu, O Bernus, C Bradley, ...
Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2011
3142011
Heterogeneous three-dimensional anatomical and electrophysiological model of human atria
G Seemann, C Höper, FB Sachse, O Dössel, AV Holden, H Zhang
Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2006
2782006
Cardiac cell modelling: observations from the heart of the cardiac physiome project
M Fink, SA Niederer, EM Cherry, FH Fenton, JT Koivumäki, G Seemann, ...
Progress in biophysics and molecular biology 104 (1-3), 2-21, 2011
1882011
The acid-sensitive potassium channel TASK-1 in rat cardiac muscle
C Putzke, K Wemhöner, FB Sachse, S Rinné, G Schlichthörl, XT Li, L Jaé, ...
Cardiovascular research 75 (1), 59-68, 2007
1802007
The molecular basis of chloroquine block of the inward rectifier Kir2. 1 channel
AA Rodríguez-Menchaca, RA Navarro-Polanco, T Ferrer-Villada, J Rupp, ...
Proceedings of the National Academy of Sciences 105 (4), 1364-1368, 2008
1532008
Subcellular structures and function of myocytes impaired during heart failure are restored by cardiac resynchronization therapy
FB Sachse, NS Torres, E Savio-Galimberti, T Aiba, DA Kass, GF Tomaselli, ...
Circulation research 110 (4), 588-597, 2012
1332012
Electrophysiological modeling of fibroblasts and their interaction with myocytes
FB Sachse, AP Moreno, JA Abildskov
Annals of biomedical engineering 36, 41-56, 2008
1222008
TASK-1 channels may modulate action potential duration of human atrial cardiomyocytes
SH Limberg, MF Netter, C Rolfes, S Rinné, G Schlichthörl, M Zuzarte, ...
Cellular Physiology and Biochemistry 28 (4), 613-624, 2011
992011
Novel features of the rabbit transverse tubular system revealed by quantitative analysis of three-dimensional reconstructions from confocal images
E Savio-Galimberti, J Frank, M Inoue, JI Goldhaber, MB Cannell, ...
Biophysical journal 95 (4), 2053-2062, 2008
932008
Gain-of-function mutations in the calcium channel CACNA1C (Cav1. 2) cause non-syndromic long-QT but not Timothy syndrome
K Wemhöner, C Friedrich, B Stallmeyer, AJ Coffey, A Grace, S Zumhagen, ...
Journal of molecular and cellular cardiology 80, 186-195, 2015
922015
Framework for modular, flexible and efficient solving the cardiac bidomain equations using PETSc
G Seemann, FB Sachse, M Karl, DL Weiss, V Heuveline, O Dössel
Progress in industrial mathematics at ECMI 2008, 363-369, 2010
912010
Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator
M Perry, FB Sachse, MC Sanguinetti
Proceedings of the National Academy of Sciences 104 (34), 13827-13832, 2007
912007
Knock-out of the potassium channel TASK-1 leads to a prolonged QT interval and a disturbed QRS complex
N Decher, K Wemhöner, S Rinné, MF Netter, M Zuzarte, MI Aller, ...
Cellular Physiology and Biochemistry 28 (1), 77-86, 2011
902011
A model of electrical conduction in cardiac tissue including fibroblasts
FB Sachse, AP Moreno, G Seemann, JA Abildskov
Annals of biomedical engineering 37, 874-889, 2009
872009
Sheet-like remodeling of the transverse tubular system in human heart failure impairs excitation-contraction coupling and functional recovery by mechanical unloading
T Seidel, S Navankasattusas, A Ahmad, NA Diakos, WD Xu, ...
Circulation 135 (17), 1632-1645, 2017
842017
Myocardial atrophy and chronic mechanical unloading of the failing human heart: implications for cardiac assist device–induced myocardial recovery
NA Diakos, CH Selzman, FB Sachse, J Stehlik, AG Kfoury, ...
Journal of the American College of Cardiology 64 (15), 1602-1612, 2014
792014
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Artículos 1–20