| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13159* | 2021 |
| PINK1-dependent recruitment of Parkin to mitochondria in mitophagy C Vives-Bauza, C Zhou, Y Huang, M Cui, RLA De Vries, J Kim, J May, ... Proceedings of the National Academy of Sciences 107 (1), 378-383, 2010 | 1838 | 2010 |
| Molecular pathophysiology of Parkinson's disease DJ Moore, AB West, VL Dawson, TM Dawson Annu. Rev. Neurosci. 28, 57-87, 2005 | 1561 | 2005 |
| Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity AB West, DJ Moore, S Biskup, A Bugayenko, WW Smith, CA Ross, ... Proceedings of the National Academy of Sciences 102 (46), 16842-16847, 2005 | 1375 | 2005 |
| AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1 AI Muir, L Chamberlain, NA Elshourbagy, D Michalovich, DJ Moore, ... Journal of Biological Chemistry 276 (31), 28969-28975, 2001 | 1172 | 2001 |
| Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity AB West, DJ Moore, C Choi, SA Andrabi, X Li, D Dikeman, S Biskup, ... Human molecular genetics 16 (2), 223-232, 2007 | 699 | 2007 |
| α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer B Fauvet, MK Mbefo, MB Fares, C Desobry, S Michael, MT Ardah, E Tsika, ... Journal of Biological Chemistry 287 (19), 15345-15364, 2012 | 651 | 2012 |
| Localization of LRRK2 to membranous and vesicular structures in mammalian brain S Biskup, DJ Moore, F Celsi, S Higashi, AB West, SA Andrabi, K Kurkinen, ... Annals of Neurology: Official Journal of the American Neurological …, 2006 | 641 | 2006 |
| Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration WW Smith, Z Pei, H Jiang, DJ Moore, Y Liang, AB West, VL Dawson, ... Proceedings of the National Academy of Sciences 102 (51), 18676-18681, 2005 | 557 | 2005 |
| Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis LI Zhang, M Shimoji, B Thomas, DJ Moore, SW Yu, NI Marupudi, R Torp, ... Human molecular genetics 14 (14), 2063-2073, 2005 | 545 | 2005 |
| Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2 D Ramonet, JPL Daher, BM Lin, K Stafa, J Kim, R Banerjee, M Westerlund, ... PloS one 6 (4), e18568, 2011 | 459 | 2011 |
| Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress DJ Moore, L Zhang, J Troncoso, MK Lee, N Hattori, Y Mizuno, TM Dawson, ... Human molecular genetics 14 (1), 71-84, 2005 | 320 | 2005 |
| A missense mutation (L166P) in DJ‐1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo‐oligomerization DJ Moore, L Zhang, TM Dawson, VL Dawson Journal of neurochemistry 87 (6), 1558-1567, 2003 | 281 | 2003 |
| Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1 L Glauser, S Sonnay, K Stafa, DJ Moore Journal of neurochemistry 118 (4), 636-645, 2011 | 261 | 2011 |
| The chaperone activity of heat shock protein 90 is critical for maintaining the stability of leucine-rich repeat kinase 2 L Wang, C Xie, E Greggio, L Parisiadou, H Shim, L Sun, J Chandran, ... Journal of Neuroscience 28 (13), 3384-3391, 2008 | 227 | 2008 |
| GTPase activity plays a key role in the pathobiology of LRRK2 Y Xiong, CE Coombes, A Kilaru, X Li, AD Gitler, WJ Bowers, VL Dawson, ... PLoS genetics 6 (4), e1000902, 2010 | 223 | 2010 |
| CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity HS Ko, R Bailey, WW Smith, Z Liu, JH Shin, YI Lee, YJ Zhang, H Jiang, ... Proceedings of the National Academy of Sciences 106 (8), 2897-2902, 2009 | 208 | 2009 |
| Localization of Parkinson’s disease-associated LRRK2 in normal and pathological human brain S Higashi, S Biskup, AB West, D Trinkaus, VL Dawson, RLM Faull, ... Brain research 1155, 208-219, 2007 | 197 | 2007 |
| Dynamic and redundant regulation of LRRK2 and LRRK1 expression S Biskup, DJ Moore, A Rea, B Lorenz-Deperieux, CE Coombes, ... BMC neuroscience 8, 1-11, 2007 | 196 | 2007 |
| Regional and cellular distribution of the P2Y1 purinergic receptor in the human brain: Striking neuronal localisation D Moore, J Chambers, H Waldvogel, R Faull, P Emson Journal of Comparative Neurology 421 (3), 374-384, 2000 | 192 | 2000 |
Ted M. DawsonDirector, Institute for Cell Engineering, Professor of Neurology and Neuroscience, JHUSoMVerified email at jhmi.edu
