Timothy Radstake
Timothy Radstake
Professor of translational Immunology, dept. of Rheumatology & Clinical Immunology, Laboratory of
Dirección de correo verificada de umcutrecht.nl
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Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
EA Stahl, S Raychaudhuri, EF Remmers, G Xie, S Eyre, BP Thomson, Y Li, ...
Nature genetics 42 (6), 508, 2010
12382010
2016 American College of Rheumatology/European League Against Rheumatism classification criteria for primary Sjögren's syndrome: a consensus and data-driven methodology …
CH Shiboski, SC Shiboski, R Seror, LA Criswell, M Labetoulle, ...
Annals of the rheumatic diseases 76 (1), 9-16, 2017
6782017
Expression and activity of citrullinating peptidylarginine deiminase enzymes in monocytes and macrophages
ER Vossenaar, TRD Radstake, A van der Heijden, MAM van Mansum, ...
Annals of the rheumatic diseases 63 (4), 373-381, 2004
4652004
Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis
S Abdollahi-Roodsaz, LAB Joosten, MI Koenders, I Devesa, MF Roelofs, ...
The Journal of clinical investigation 118 (1), 205-216, 2008
4592008
Guidelines for the use of flow cytometry and cell sorting in immunological studies
A Cossarizza, HD Chang, A Radbruch, M Akdis, I Andrä, F Annunziato, ...
European journal of immunology 47 (10), 1584-1797, 2017
4492017
Formation of antibodies against infliximab and adalimumab strongly correlates with functional drug levels and clinical responses in rheumatoid arthritis
TRDJ Radstake, M Svenson, AM Eijsbouts, FHJ van den Hoogen, ...
Annals of the rheumatic diseases 68 (11), 1739-1745, 2009
4152009
The expression of toll‐like receptors 3 and 7 in rheumatoid arthritis synovium is increased and costimulation of toll‐like receptors 3, 4, and 7/8 results in synergistic …
MF Roelofs, LAB Joosten, S Abdollahi‐Roodsaz, AWT Van Lieshout, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2005
3632005
Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus
TRDJ Radstake, O Gorlova, B Rueda, JE Martin, BZ Alizadeh, ...
Nature genetics 42 (5), 426-429, 2010
3582010
IL-32, a proinflammatory cytokine in rheumatoid arthritis
LAB Joosten, MG Netea, SH Kim, DY Yoon, B Oppers-Walgreen, ...
Proceedings of the National Academy of Sciences 103 (9), 3298-3303, 2006
3502006
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci
A Zhernakova, EA Stahl, G Trynka, S Raychaudhuri, EA Festen, L Franke, ...
PLoS Genet 7 (2), e1002004, 2011
3442011
Expression of Toll‐like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin‐12 and interleukin‐18 via interferon‐γ
TRDJ Radstake, MF Roelofs, YM Jenniskens, B Oppers‐Walgreen, ...
Arthritis & Rheumatism 50 (12), 3856-3865, 2004
3392004
Systematic validation of specific phenotypic markers for in vitro polarized human macrophages
CA Ambarus, S Krausz, M van Eijk, J Hamann, T Radstake, KA Reedquist, ...
Journal of immunological methods 375 (1-2), 196-206, 2012
3252012
Inhibition of Toll‐like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis
S Abdollahi‐Roodsaz, LAB Joosten, MF Roelofs, TRDJ Radstake, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2007
3132007
Identification of small heat shock protein B8 (HSP22) as a novel TLR4 ligand and potential involvement in the pathogenesis of rheumatoid arthritis
MF Roelofs, WC Boelens, LAB Joosten, S Abdollahi-Roodsaz, J Geurts, ...
The Journal of Immunology 176 (11), 7021-7027, 2006
3012006
Influence of anti-tumour necrosis factor therapy on cardiovascular risk factors in patients with active rheumatoid arthritis
C Popa, MG Netea, T Radstake, JWM Van der Meer, AFH Stalenhoef, ...
Annals of the rheumatic diseases 64 (2), 303-305, 2005
2792005
Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis
L van Bon, AJ Affandi, J Broen, RB Christmann, RJ Marijnissen, L Stawski, ...
New England journal of medicine 370 (5), 433-443, 2014
2772014
Novel association in chromosome 4q27 region with rheumatoid arthritis and confirmation of type 1 diabetes point to a general risk locus for autoimmune diseases
A Zhernakova, BZ Alizadeh, M Bevova, MA van Leeuwen, MJH Coenen, ...
The American Journal of Human Genetics 81 (6), 1284-1288, 2007
2402007
Correlation of rheumatoid arthritis severity with the genetic functional variants and circulating levels of macrophage migration inhibitory factor
TRDJ Radstake, FCGJ Sweep, P Welsing, B Franke, SHHM Vermeulen, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2005
2212005
Markers of inflammation are negatively correlated with serum leptin in rheumatoid arthritis
C Popa, MG Netea, TRDS Radstake, PL van Riel, P Barrera, ...
Annals of the Rheumatic Diseases 64 (8), 1195-1198, 2005
2192005
Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma
S Bhattacharyya, K Kelley, DS Melichian, Z Tamaki, F Fang, Y Su, G Feng, ...
The American journal of pathology 182 (1), 192-205, 2013
1982013
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