| Primary cilia regulate mTORC1 activity and cell size through Lkb1 C Boehlke, F Kotsis, V Patel, S Braeg, H Voelker, S Bredt, T Beyer, ... Nature cell biology 12 (11), 1115-1122, 2010 | 422 | 2010 |
| Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia V Patel, L Li, P Cobo-Stark, X Shao, S Somlo, F Lin, P Igarashi Human molecular genetics 17 (11), 1578-1590, 2008 | 378 | 2008 |
| Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys M Baba, M Furihata, SB Hong, L Tessarollo, DC Haines, E Southon, ... Journal of the National Cancer Institute 100 (2), 140-154, 2008 | 281 | 2008 |
| Advances in the pathogenesis and treatment of polycystic kidney disease V Patel, R Chowdhury, P Igarashi Current opinion in nephrology and hypertension 18 (2), 99-106, 2009 | 210 | 2009 |
| MicroRNAs and fibrosis V Patel, L Noureddine Current opinion in nephrology and hypertension 21 (4), 410-416, 2012 | 203 | 2012 |
| miR-17∼ 92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease V Patel, D Williams, S Hajarnis, R Hunter, M Pontoglio, S Somlo, ... Proceedings of the National Academy of Sciences 110 (26), 10765-10770, 2013 | 179 | 2013 |
| microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism S Hajarnis, R Lakhia, M Yheskel, D Williams, M Sorourian, X Liu, ... Nature communications 8 (1), 1-15, 2017 | 172 | 2017 |
| Loss of oriented cell division does not initiate cyst formation S Nishio, X Tian, AR Gallagher, Z Yu, V Patel, P Igarashi, S Somlo Journal of the American Society of Nephrology 21 (2), 295-302, 2010 | 163 | 2010 |
| Discovery and preclinical evaluation of anti-miR-17 oligonucleotide RGLS4326 for the treatment of polycystic kidney disease EC Lee, T Valencia, C Allerson, A Schairer, A Flaten, M Yheskel, ... Nature communications 10 (1), 4148, 2019 | 111 | 2019 |
| MicroRNAs regulate renal tubule maturation through modulation of Pkd1 V Patel, S Hajarnis, D Williams, R Hunter, D Huynh, P Igarashi Journal of the American Society of Nephrology 23 (12), 1941-1948, 2012 | 103 | 2012 |
| PPARα agonist fenofibrate enhances fatty acid β-oxidation and attenuates polycystic kidney and liver disease in mice R Lakhia, M Yheskel, A Flaten, EB Quittner-Strom, WL Holland, V Patel American Journal of Physiology-Renal Physiology 314 (1), F122-F131, 2018 | 102 | 2018 |
| Fluid flow induces mechanosensitive ATP release, calcium signalling and Cl− transport in biliary epithelial cells through a PKCζ‐dependent pathway K Woo, AK Dutta, V Patel, C Kresge, AP Feranchak The Journal of physiology 586 (11), 2779-2798, 2008 | 95 | 2008 |
| HNF-1β regulates transcription of the PKD modifier gene Kif12 Y Gong, Z Ma, V Patel, E Fischer, T Hiesberger, M Pontoglio, P Igarashi Journal of the American Society of Nephrology 20 (1), 41-47, 2009 | 78 | 2009 |
| Mutations of HNF-1β inhibit epithelial morphogenesis through dysregulation of SOCS-3 Z Ma, Y Gong, V Patel, CM Karner, E Fischer, T Hiesberger, TJ Carroll, ... Proceedings of the National Academy of Sciences 104 (51), 20386-20391, 2007 | 75 | 2007 |
| MicroRNA-21 aggravates cyst growth in a model of polycystic kidney disease R Lakhia, S Hajarnis, D Williams, K Aboudehen, M Yheskel, C Xing, ... Journal of the American Society of Nephrology 27 (8), 2319-2330, 2016 | 74 | 2016 |
| A methionine-Mettl3-N6-methyladenosine axis promotes polycystic kidney disease H Ramalingam, S Kashyap, P Cobo-Stark, A Flaten, CM Chang, ... Cell metabolism 33 (6), 1234-1247. e7, 2021 | 54 | 2021 |
| Transcription Factor HNF-1β Regulates MicroRNA-200 Expression Through a Long Noncoding RNA IP Hajarnis SS, Patel V, Aboudehen K, Attanasio M, Cobo-Stark P, Pontoglio M J Biol Chem, 2015 | 49* | 2015 |
| Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning H Brzoska, AM d’Esposito, M Kolatsi-Joannou, V Patel, P Igarashi, Y Lei, ... Kidney international 90 (6), 1274-1284, 2016 | 48 | 2016 |
| Suppression of microRNA activity in kidney collecting ducts induces partial loss of epithelial phenotype and renal fibrosis S Hajarnis, M Yheskel, D Williams, T Brefort, B Glaudemans, H Debaix, ... Journal of the American Society of Nephrology 29 (2), 518-531, 2018 | 47 | 2018 |
| Interstitial microRNA miR-214 attenuates inflammation and polycystic kidney disease progression R Lakhia, M Yheskel, A Flaten, H Ramalingam, K Aboudehen, S Ferrè, ... JCI insight 5 (7), 2020 | 45 | 2020 |
Sachin HajarnisUT Southwestern Medical Center at DallasDirección de correo verificada de utsouthwestern.edu
