| A pharmacological map of the PI3-K family defines a role for p110α in insulin signaling ZA Knight, B Gonzalez, ME Feldman, ER Zunder, DD Goldenberg, ... Cell 125 (4), 733-747, 2006 | 1387 | 2006 |
| Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases B Apsel, JA Blair, B Gonzalez, TM Nazif, ME Feldman, B Aizenstein, ... Nature chemical biology 4 (11), 691, 2008 | 555 | 2008 |
| ESCRT-II, an endosome-associated complex required for protein sorting: crystal structure and interactions with ESCRT-III and membranes H Teo, O Perisic, B González, RL Williams Developmental cell 7 (4), 559-569, 2004 | 292 | 2004 |
| Three-dimensional structure of Saccharomyces invertase: role of a non-catalytic domain in oligomerization and substrate specificity MA Sainz-Polo, M Ramírez-Escudero, A Lafraya, B González, ... Journal of Biological Chemistry 288 (14), 9755-9766, 2013 | 127 | 2013 |
| Directed evolution of β-glucosidase A from Paenibacillus polymyxa to thermal resistance G González-Blasco, J Sanz-Aparicio, B González, JA Hermoso, J Polaina Journal of Biological Chemistry 275 (18), 13708-13712, 2000 | 116 | 2000 |
| Structure of a human inositol 1, 4, 5-trisphosphate 3-kinase: substrate binding reveals why it is not a phosphoinositide 3-kinase B González, MJ Schell, AJ Letcher, DB Veprintsev, RF Irvine, RL Williams Molecular cell 15 (5), 689-701, 2004 | 101 | 2004 |
| Structural and kinetic analysis of Schwanniomyces occidentalis invertase reveals a new oligomerization pattern and the role of its supplementary domain in substrate binding M Álvaro-Benito, A Polo, B González, M Fernández-Lobato, ... Journal of biological chemistry 285 (18), 13930-13941, 2010 | 95 | 2010 |
| The crystal structure of tetrameric methionine adenosyltransferase from rat liver reveals the methionine-binding site B González, MA Pajares, JA Hermoso, L Alvarez, F Garrido, JR Sufrin, ... Journal of molecular biology 300 (2), 363-375, 2000 | 87 | 2000 |
| Crystal structures of Paenibacillus polymyxa β-glucosidase B complexes reveal the molecular basis of substrate specificity and give new insights into the catalytic machinery of … P Isorna, J Polaina, L Latorre-García, SAJ Canada FJ, Gonzalez B J. Mol. Biol 371 (5), 1204-1218, 2007 | 86 | 2007 |
| Crystal structures of methionine adenosyltransferase complexed with substrates and products reveal the methionine-ATP recognition and give insights into the catalytic mechanism B González, MA Pajares, JA Hermoso, D Guillerm, G Guillerm, ... Journal of molecular biology 331 (2), 407-416, 2003 | 69 | 2003 |
| Structural insights into the specificity of Xyn10B from Paenibacillus barcinonensis and its improved stability by forced protein evolution O Gallardo, FIJ Pastor, J Polaina, P Diaz, R Łysek, P Vogel, P Isorna, ... Journal of biological chemistry 285 (4), 2721-2733, 2010 | 63 | 2010 |
| Inositol 1, 3, 4, 5, 6-pentakisphosphate 2-kinase is a distant IPK member with a singular inositide binding site for axial 2-OH recognition B González, JI Baños-Sanz, M Villate, CA Brearley, J Sanz-Aparicio Proceedings of the National Academy of Sciences 107 (21), 9608-9613, 2010 | 59 | 2010 |
| Crystal structure of rat liver betaine homocysteine s-methyltransferase reveals new oligomerization features and conformational changes upon substrate binding B González, MA Pajares, M Martı́nez-Ripoll, TL Blundell, J Sanz-Aparicio Journal of molecular biology 338 (4), 771-782, 2004 | 56 | 2004 |
| Structural analysis of β-fructofuranosidase from Xanthophyllomyces dendrorhous reveals unique features and the crucial role of N-glycosylation in oligomerization and activity M Ramírez-Escudero, M Gimeno-Pérez, B González, D Linde, Z Merdzo, ... Journal of Biological Chemistry 291 (13), 6843-6857, 2016 | 54 | 2016 |
| Structural and kinetic insights reveal that the amino acid pair Gln-228/Asn-254 modulates the transfructosylating specificity of Schwanniomyces occidentalis β … M Álvaro-Benito, MA Sainz-Polo, D González-Pérez, B González, FJ Plou, ... Journal of biological chemistry 287 (23), 19674-19686, 2012 | 48 | 2012 |
| Diels−Alder Cycloadducts of [60]Fullerene with Pyrimidine o-Quinodimethanes B González, A Herrera, B Illescas, N Martín, R Martínez, F Moreno, ... The Journal of Organic Chemistry 63 (20), 6807-6813, 1998 | 41 | 1998 |
| Structural analysis of glucuronoxylan-specific Xyn30D and its attached CBM35 domain gives insights into the role of modularity in specificity MA Sainz-Polo, SV Valenzuela, B Gonzalez, FIJ Pastor, J Sanz-Aparicio Journal of Biological Chemistry 289 (45), 31088-31101, 2014 | 39 | 2014 |
| Structural basis of increased resistance to thermal denaturation induced by single amino acid substitution in the sequence of β‐glucosidase A from Bacillus polymyxa J Sanz‐Aparicio, JA Hermoso, M Martínez‐Ripoll, B Gonzalez, ... Proteins: Structure, Function, and Bioinformatics 33 (4), 567-576, 1998 | 37 | 1998 |
| Crystal structure and functional insights into uracil-DNA glycosylase inhibition by phage ϕ29 DNA mimic protein p56 JI Banos-Sanz, L Mojardín, J Sanz-Aparicio, JM Lazaro, L Villar, ... Nucleic acids research 41 (13), 6761-6773, 2013 | 31 | 2013 |
| An expeditious procedure for the generation of pyrimidine ortho-quinodimethanes A Herrera, R Martínez, B González, B Illescas, M Nazario, C Seoane Tetrahedron letters 38 (27), 4873-4876, 1997 | 31 | 1997 |
