The cell cycle is a redox cycle: linking phase-specific targets to cell fate WC Burhans, NH Heintz Free Radical Biology and Medicine 47 (9), 1282-1293, 2009 | 432 | 2009 |
Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducing H2O2 and superoxide dismutase activity A Mesquita, M Weinberger, A Silva, B Sampaio-Marques, B Almeida, ... Proceedings of the National Academy of Sciences 107 (34), 15123-15128, 2010 | 341 | 2010 |
Identification of an origin of bidirectional DNA replication in mammalian chromosomes WC Burhans, LT Vassilev, MS Caddle, NH Heintz, ML DePamphills Cell 62 (5), 955-965, 1990 | 328 | 1990 |
DNA replication stress, genome instability and aging WC Burhans, M Weinberger Nucleic acids research 35 (22), 7545-7556, 2007 | 321 | 2007 |
Site-specific DNA cleavage within the MLL breakpoint cluster region induced by topoisomerase II inhibitors [see comments] PD Aplan, DS Chervinsky, M Stanulla, WC Burhans | 207 | 1996 |
Guidelines and recommendations on yeast cell death nomenclature D Carmona-Gutierrez, MA Bauer, A Zimmermann, A Aguilera, N Austriaco, ... Microbial Cell 5 (1), 4, 2018 | 186 | 2018 |
Mimosine Arrests DNA Synthesis at Replication Forks by Inhibiting Deoxyribonucleotide Metabolism (∗) DM Gilbert, A Neilson, H Miyazawa, ML DePamphilis, WC Burhans Journal of Biological Chemistry 270 (16), 9597-9606, 1995 | 162 | 1995 |
Yno1p/Aim14p, a NADPH-oxidase ortholog, controls extramitochondrial reactive oxygen species generation, apoptosis, and actin cable formation in yeast M Rinnerthaler, S Büttner, P Laun, G Heeren, TK Felder, H Klinger, ... Proceedings of the National Academy of Sciences 109 (22), 8658-8663, 2012 | 160 | 2012 |
Retrotransposition is associated with genome instability during chronological aging PH Maxwell, WC Burhans, MJ Curcio Proceedings of the National Academy of Sciences 108 (51), 20376-20381, 2011 | 156 | 2011 |
Mapping an origin of DNA replication at a single-copy locus in exponentially proliferating mammalian cells LT Vassilev, WC Burhans, ML Depamphilis Molecular and cellular biology, 1990 | 156 | 1990 |
Apoptosis-like yeast cell death in response to DNA damage and replication defects WC Burhans, M Weinberger, MA Marchetti, L Ramachandran, G D’Urso, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 532 (1 …, 2003 | 140 | 2003 |
Emetine allows identification of origins of mammalian DNA replication by imbalanced DNA synthesis, not through conservative nucleosome segregation. WC Burhans, LT Vassilev, J Wu, JM Sogo, FS Nallaseth, ML DePamphilis The EMBO Journal 10 (13), 4351-4360, 1991 | 138 | 1991 |
Growth signaling promotes chronological aging in budding yeast by inducing superoxide anions that inhibit quiescence M Weinberger, A Mesquita, T Carroll, L Marks, H Yang, Z Zhang, ... Aging (Albany NY) 2 (10), 709, 2010 | 135 | 2010 |
Isolation of the origin of replication associated with the amplified Chinese hamster dihydrofolate reductase domain. WC Burhans, JE Selegue, NH Heintz Proceedings of the National Academy of Sciences 83 (20), 7790-7794, 1986 | 132 | 1986 |
DNA replication stress is a determinant of chronological lifespan in budding yeast M Weinberger, L Feng, A Paul, DL Smith Jr, RD Hontz, JS Smith, M Vujcic, ... PloS one 2 (8), e748, 2007 | 126 | 2007 |
An anoxia inducible endonuclease and enhanced DNA breakage as contributors to genomic instability in cancer CA Russo, TK Weber, CM Volpe, DL Stoler, NJ Petrelli, ... Cancer research 55 (5), 1122-1128, 1995 | 115 | 1995 |
Apoptosis in budding yeast caused by defects in initiation of DNA replication M Weinberger, L Ramachandran, L Feng, K Sharma, X Sun, M Marchetti, ... Journal of Cell Science 118 (15), 3543-3553, 2005 | 100 | 2005 |
Targeted destruction of DNA replication protein Cdc6 by cell death pathways in mammals and yeast F Blanchard, ME Rusiniak, K Sharma, X Sun, I Todorov, MM Castellano, ... Molecular biology of the cell 13 (5), 1536-1549, 2002 | 99 | 2002 |
A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway MA Marchetti, S Kumar, E Hartsuiker, M Maftahi, AM Carr, GA Freyer, ... Proceedings of the National Academy of Sciences 99 (11), 7472-7477, 2002 | 95 | 2002 |
Reactive oxygen species, ageing and the hormesis police P Ludovico, WC Burhans FEMS yeast research 14 (1), 33-39, 2014 | 94 | 2014 |