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James S. Italia, Ph.D.
James S. Italia, Ph.D.
BrickBio, formerly Boston College Chemistry Department
Verified email at brickbio.com
Title
Cited by
Cited by
Year
An orthogonalized platform for genetic code expansion in both bacteria and eukaryotes
JS Italia, PS Addy, CJJ Wrobel, LA Crawford, MJ Lajoie, Y Zheng, ...
Nature chemical biology 13 (4), 446-450, 2017
1252017
Mutually orthogonal nonsense-suppression systems and conjugation chemistries for precise protein labeling at up to three distinct sites
JS Italia, PS Addy, SB Erickson, JC Peeler, E Weerapana, A Chatterjee
Journal of the American Chemical Society 141 (15), 6204-6212, 2019
992019
A chemoselective rapid azo-coupling reaction (CRACR) for unclickable bioconjugation
PS Addy, SB Erickson, JS Italia, A Chatterjee
Journal of the American Chemical Society 139 (34), 11670-11673, 2017
932017
Genetically encoded protein sulfation in mammalian cells
JS Italia, JC Peeler, CM Hillenbrand, C Latour, E Weerapana, ...
Nature chemical biology 16 (4), 379-382, 2020
602020
Expanding the genetic code of mammalian cells
JS Italia, Y Zheng, RE Kelemen, SB Erickson, PS Addy, A Chatterjee
Biochemical Society transactions 45 (2), 555-562, 2017
602017
Resurrecting the bacterial tyrosyl-tRNA Synthetase/tRNA pair for expanding the genetic code of both E. coli and eukaryotes
JS Italia, C Latour, CJJ Wrobel, A Chatterjee
Cell chemical biology 25 (10), 1304-1312. e5, 2018
562018
Performance of optimized noncanonical amino acid mutagenesis systems in the absence of release factor 1
Y Zheng, MJ Lajoie, JS Italia, MA Chin, GM Church, A Chatterjee
Molecular BioSystems 12 (6), 1746-1749, 2016
482016
Synthesis and characterization of an unnatural boron and nitrogen-containing tryptophan analogue and its incorporation into proteins
K Boknevitz, JS Italia, B Li, A Chatterjee, SY Liu
Chemical Science 10 (19), 4994-4998, 2019
262019
Structural robustness affects the engineerability of aminoacyl-tRNA synthetases for genetic code expansion
KT Grasso, MJR Yeo, CM Hillenbrand, ED Ficaretta, JS Italia, RL Huang, ...
Biochemistry 60 (7), 489-493, 2021
252021
An Efficient Opal‐Suppressor Tryptophanyl Pair Creates New Routes for Simultaneously Incorporating up to Three Distinct Noncanonical Amino Acids into Proteins in Mammalian Cells
AO Osgood, Y Zheng, SJS Roy, N Biris, M Hussain, C Loynd, D Jewel, ...
Angewandte Chemie 135 (19), e202219269, 2023
112023
A “Quenchergenic” chemoselective protein labeling strategy
PS Addy, Y Zheng, JS Italia, A Chatterjee
ChemBioChem 20 (13), 1659-1663, 2019
112019
An oxidative bioconjugation strategy targeted to a genetically encoded 5‐hydroxytryptophan
P Sarathi Addy, JS Italia, A Chatterjee
ChemBioChem 19 (13), 1375-1378, 2018
112018
A robust platform for unnatural amino acid mutagenesis in E. coli using the bacterial tryptophanyl-tRNA synthetase/tRNA pair
ED Ficaretta, CJJ Wrobel, SJS Roy, SB Erickson, JS Italia, A Chatterjee
Journal of molecular biology 434 (8), 167304, 2022
82022
Labeling proteins at site-specifically incorporated 5-Hydroxytryptophan residues using a chemoselective rapid Azo-coupling reaction
PS Addy, SB Erickson, JS Italia, A Chatterjee
Bioconjugation: Methods and Protocols, 239-251, 2019
62019
A site-specific approach to improved antibody-drug conjugates.
J Italia
Journal of Clinical Oncology 38 (15_suppl), e13009-e13009, 2020
12020
Protein derivatives containing unnatural amino acids and branched linkers
JS Italia
US Patent App. 18/254,308, 2024
2024
Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability
Y Feng, J Lee, L Yang, MB Hilton, K Morris, S Seaman, VVSR Edupuganti, ...
Cell reports 42 (12), 2023
2023
Stable cell lines for site-specific incorporation of unnatural amino acids
JS Italia, Z Li
US Patent App. 18/040,933, 2023
2023
Universal platform for genetic code expansion
A Chatterjee, J Italia
US Patent 11,760,990, 2023
2023
Unlocking the therapeutic index of highly potent site-specific ADCs in solid tumors
JS Italia, CA Souders, SR Suthe, M Hussain, Z Li, J Boyce, A Warner, ...
Cancer Research 83 (7_Supplement), 1521-1521, 2023
2023
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Articles 1–20