An orthogonalized platform for genetic code expansion in both bacteria and eukaryotes JS Italia, PS Addy, CJJ Wrobel, LA Crawford, MJ Lajoie, Y Zheng, ... Nature chemical biology 13 (4), 446-450, 2017 | 125 | 2017 |
Mutually orthogonal nonsense-suppression systems and conjugation chemistries for precise protein labeling at up to three distinct sites JS Italia, PS Addy, SB Erickson, JC Peeler, E Weerapana, A Chatterjee Journal of the American Chemical Society 141 (15), 6204-6212, 2019 | 99 | 2019 |
A chemoselective rapid azo-coupling reaction (CRACR) for unclickable bioconjugation PS Addy, SB Erickson, JS Italia, A Chatterjee Journal of the American Chemical Society 139 (34), 11670-11673, 2017 | 93 | 2017 |
Genetically encoded protein sulfation in mammalian cells JS Italia, JC Peeler, CM Hillenbrand, C Latour, E Weerapana, ... Nature chemical biology 16 (4), 379-382, 2020 | 60 | 2020 |
Expanding the genetic code of mammalian cells JS Italia, Y Zheng, RE Kelemen, SB Erickson, PS Addy, A Chatterjee Biochemical Society transactions 45 (2), 555-562, 2017 | 60 | 2017 |
Resurrecting the bacterial tyrosyl-tRNA Synthetase/tRNA pair for expanding the genetic code of both E. coli and eukaryotes JS Italia, C Latour, CJJ Wrobel, A Chatterjee Cell chemical biology 25 (10), 1304-1312. e5, 2018 | 56 | 2018 |
Performance of optimized noncanonical amino acid mutagenesis systems in the absence of release factor 1 Y Zheng, MJ Lajoie, JS Italia, MA Chin, GM Church, A Chatterjee Molecular BioSystems 12 (6), 1746-1749, 2016 | 48 | 2016 |
Synthesis and characterization of an unnatural boron and nitrogen-containing tryptophan analogue and its incorporation into proteins K Boknevitz, JS Italia, B Li, A Chatterjee, SY Liu Chemical Science 10 (19), 4994-4998, 2019 | 26 | 2019 |
Structural robustness affects the engineerability of aminoacyl-tRNA synthetases for genetic code expansion KT Grasso, MJR Yeo, CM Hillenbrand, ED Ficaretta, JS Italia, RL Huang, ... Biochemistry 60 (7), 489-493, 2021 | 25 | 2021 |
An Efficient Opal‐Suppressor Tryptophanyl Pair Creates New Routes for Simultaneously Incorporating up to Three Distinct Noncanonical Amino Acids into Proteins in Mammalian Cells AO Osgood, Y Zheng, SJS Roy, N Biris, M Hussain, C Loynd, D Jewel, ... Angewandte Chemie 135 (19), e202219269, 2023 | 11 | 2023 |
A “Quenchergenic” chemoselective protein labeling strategy PS Addy, Y Zheng, JS Italia, A Chatterjee ChemBioChem 20 (13), 1659-1663, 2019 | 11 | 2019 |
An oxidative bioconjugation strategy targeted to a genetically encoded 5‐hydroxytryptophan P Sarathi Addy, JS Italia, A Chatterjee ChemBioChem 19 (13), 1375-1378, 2018 | 11 | 2018 |
A robust platform for unnatural amino acid mutagenesis in E. coli using the bacterial tryptophanyl-tRNA synthetase/tRNA pair ED Ficaretta, CJJ Wrobel, SJS Roy, SB Erickson, JS Italia, A Chatterjee Journal of molecular biology 434 (8), 167304, 2022 | 8 | 2022 |
Labeling proteins at site-specifically incorporated 5-Hydroxytryptophan residues using a chemoselective rapid Azo-coupling reaction PS Addy, SB Erickson, JS Italia, A Chatterjee Bioconjugation: Methods and Protocols, 239-251, 2019 | 6 | 2019 |
A site-specific approach to improved antibody-drug conjugates. J Italia Journal of Clinical Oncology 38 (15_suppl), e13009-e13009, 2020 | 1 | 2020 |
Protein derivatives containing unnatural amino acids and branched linkers JS Italia US Patent App. 18/254,308, 2024 | | 2024 |
Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability Y Feng, J Lee, L Yang, MB Hilton, K Morris, S Seaman, VVSR Edupuganti, ... Cell reports 42 (12), 2023 | | 2023 |
Stable cell lines for site-specific incorporation of unnatural amino acids JS Italia, Z Li US Patent App. 18/040,933, 2023 | | 2023 |
Universal platform for genetic code expansion A Chatterjee, J Italia US Patent 11,760,990, 2023 | | 2023 |
Unlocking the therapeutic index of highly potent site-specific ADCs in solid tumors JS Italia, CA Souders, SR Suthe, M Hussain, Z Li, J Boyce, A Warner, ... Cancer Research 83 (7_Supplement), 1521-1521, 2023 | | 2023 |