Carmen Ortiz Mellet
Carmen Ortiz Mellet
Professor of Organic Chemistry, University of Seville
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Cited by
Cited by
Cyclodextrin-based gene delivery systems
CO Mellet, JMG Fernández, JM Benito
Chemical Society Reviews 40 (3), 1586-1608, 2011
Optimizing saccharide-directed molecular delivery to biological receptors: Design, synthesis, and biological evaluation of glycodendrimer− cyclodextrin conjugates
JM Benito, M Gómez-García, C Ortiz Mellet, I Baussanne, J Defaye, ...
Journal of the American Chemical Society 126 (33), 10355-10363, 2004
Cyclodextrin-based multivalent glycodisplays: Covalent and supramolecular conjugates to assess carbohydrate–protein interactions
Á Martínez, CO Mellet, JMG Fernández
Chemical Society Reviews 42 (11), 4746-4773, 2013
Glycosidase inhibition with fullerene iminosugar balls: a dramatic multivalent effect
P Compain, C Decroocq, J Iehl, M Holler, D Hazelard, T Mena Barragan, ...
Angewandte Chemie 122 (33), 5889-5892, 2010
Multivalency in heterogeneous glycoenvironments: hetero-glycoclusters,-glycopolymers and-glycoassemblies
JLJ Blanco, CO Mellet, JMG Fernández
Chemical Society reviews 42 (11), 4518-4531, 2013
Probing secondary carbohydrate− protein interactions with highly dense cyclodextrin-centered heteroglycoclusters: The heterocluster effect
M Gómez-García, JM Benito, D Rodríguez-Lucena, JX Yu, K Chmurski, ...
Journal of the American Chemical Society 127 (22), 7970-7971, 2005
Multivalent iminosugars to modulate affinity and selectivity for glycosidases
J Diot, MI Garcia-Moreno, SG Gouin, CO Mellet, K Haupt, J Kovensky
Organic & biomolecular chemistry 7 (2), 357-363, 2009
Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: Lessons from Gaucher, G M1-gangliosidosis and Fabry diseases
EM Sánchez-Fernández, JMG Fernández, CO Mellet
Chemical Communications 52 (32), 5497-5515, 2016
Multivalent cyclooligosaccharides: Versatile carbohydrate clusters with dual role as molecular receptors and lectin ligands
C Ortiz Mellet, J Defaye, JM García Fernández
Chemistry–A European Journal 8 (9), 1982-1990, 2002
Pharmacological chaperone therapy for Gaucher disease: a patent review
JM Benito, JM Garcia Fernandez, CO Mellet
Expert opinion on therapeutic patents 21 (6), 885-903, 2011
Preorganized, macromolecular, gene‐delivery systems
C Ortiz Mellet, JM Benito, JM Garcia Fernandez
Chemistry–A European Journal 16 (23), 6728-6742, 2010
Polycationic amphiphilic cyclodextrins for gene delivery: synthesis and effect of structural modifications on plasmid DNA complex stability, cytotoxicity, and gene expression
A Díaz‐Moscoso, L Le Gourriérec, M Gómez‐García, JM Benito, ...
Chemistry–A European Journal 15 (46), 12871-12888, 2009
Pharmacological Chaperones and Coenzyme Q10 Treatment Improves Mutant β-Glucocerebrosidase Activity and Mitochondrial Function in Neuronopathic Forms …
M de La Mata, D Cotán, M Oropesa-Ávila, J Garrido-Maraver, MD Cordero, ...
Scientific reports 5 (1), 10903, 2015
Carbohydrate-based receptors with multiple thiourea binding sites. Multipoint hydrogen bond recognition of dicarboxylates and monosaccharides
JM Benito, M Gómez-García, JL Jiménez Blanco, C Ortiz Mellet, ...
The Journal of Organic Chemistry 66 (4), 1366-1372, 2001
Chemistry and developments of N-thiocarbonyl carbohydrate derivatives: sugar isothiocyanates, thioamides, thioureas, thiocarbamates, and their conjugates
JMG Fernández, CO Mellet
Advances in carbohydrate chemistry and biochemistry 55, 35-135, 2000
The multivalent effect in glycosidase inhibition: Probing the influence of architectural parameters with cyclodextrin‐based iminosugar click clusters
C Decroocq, D Rodríguez‐Lucena, V Russo, T Mena Barragan, ...
Chemistry–A European Journal 17 (49), 13825-13831, 2011
Isothiocyanates and cyclic thiocarbamates of α, α′-trehalose, sucrose, and cyclomaltooligosaccharides
JMG Fernández, CO Mellet, JLJ Blanco, JF Mota, A Gadelle, ...
Carbohydrate research 268 (1), 57-71, 1995
Insights in cellular uptake mechanisms of pDNA–polycationic amphiphilic cyclodextrin nanoparticles (CDplexes)
A Díaz-Moscoso, D Vercauteren, J Rejman, JM Benito, CO Mellet, ...
Journal of controlled release 143 (3), 318-325, 2010
Mannosyl-coated nanocomplexes from amphiphilic cyclodextrins and pDNA for site-specific gene delivery
A Díaz-Moscoso, N Guilloteau, C Bienvenu, A Méndez-Ardoy, JLJ Blanco, ...
Biomaterials 32 (29), 7263-7273, 2011
Fullerene‐sp2‐Iminosugar Balls as Multimodal Ligands for Lectins and Glycosidases: A Mechanistic Hypothesis for the Inhibitory Multivalent Effect
R Rísquez‐Cuadro, JM Garcia Fernandez, JF Nierengarten, C Ortiz Mellet
Chemistry–A European Journal 19 (49), 16791-16803, 2013
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