Analysis of protein-coding genetic variation in 60,706 humans M Lek, KJ Karczewski, EV Minikel, KE Samocha, E Banks, T Fennell, ... Nature 536 (7616), 285-291, 2016 | 10312 | 2016 |
Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. TSSIGM the Americas) Type 2 Diabetes Consortium Nature 506 (7486), 97–101, 2014 | 558 | 2014 |
La obesidad y el síndrome metabólico como problema de salud pública. Una reflexión. Primera parte. Salud Mental 31 (6), 489-496, 2008 | 436* | 2008 |
The power of genetic diversity in genome-wide association studies of lipids SE Graham, SL Clarke, KHH Wu, S Kanoni, GJM Zajac, S Ramdas, ... Nature 600 (7890), 675-679, 2021 | 410 | 2021 |
Transancestral mapping and genetic load in systemic lupus erythematosus CD Langefeld, HC Ainsworth, DSC Graham, JA Kelly, ME Comeau, ... Nature communications 8 (1), 16021, 2017 | 344 | 2017 |
A saturated map of common genetic variants associated with human height L Yengo, S Vedantam, E Marouli, J Sidorenko, E Bartell, S Sakaue, ... Nature 610 (7933), 704-712, 2022 | 318 | 2022 |
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation A Mahajan, CN Spracklen, W Zhang, MCY Ng, LE Petty, H Kitajima, ... Nature genetics 54 (5), 560-572, 2022 | 294 | 2022 |
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls J Flannick, JM Mercader, C Fuchsberger, MS Udler, A Mahajan, J Wessel, ... Nature 570 (7759), 71-76, 2019 | 284 | 2019 |
Association of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population K Estrada, I Aukrust, L Bjørkhaug, NP Burtt, JM Mercader, H García-Ortiz, ... Jama 311 (22), 2305-2314, 2014 | 272 | 2014 |
Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes AR Majithia, J Flannick, P Shahinian, M Guo, MA Bray, P Fontanillas, ... Proceedings of the National Academy of Sciences 111 (36), 13127-13132, 2014 | 177 | 2014 |
Reconstruction of ancient microbial genomes from the human gut MC Wibowo, Z Yang, M Borry, A Hübner, KD Huang, BT Tierney, ... Nature 594 (7862), 234-239, 2021 | 175 | 2021 |
Tuberculosis and impaired IL-23–dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant S Boisson-Dupuis, N Ramirez-Alejo, Z Li, E Patin, G Rao, G Kerner, ... Science immunology 3 (30), eaau8714, 2018 | 170 | 2018 |
STAT4 associates with systemic lupus erythematosus through two independent effects that correlate with gene expression and act additively with IRF5 to increase risk AK Abelson, AM Delgado-Vega, SV Kozyrev, E Sanchez, ... Annals of the Rheumatic Diseases 68 (11), 1746-1753, 2009 | 170 | 2009 |
Type 2 diabetes variants disrupt function of SLC16A11 through two distinct mechanisms V Rusu, E Hoch, JM Mercader, DE Tenen, M Gymrek, CR Hartigan, ... Cell 170 (1), 199-212. e20, 2017 | 153 | 2017 |
Genome‐wide association study in an Amerindian ancestry population reveals novel systemic lupus erythematosus risk loci and the role of European admixture ME Alarcón‐Riquelme, JT Ziegler, J Molineros, TD Howard, ... Arthritis & rheumatology 68 (4), 932-943, 2016 | 149 | 2016 |
Tumor necrosis factor–α is a common genetic risk factor for asthma, juvenile rheumatoid arthritis, and systemic lupus erythematosus in a Mexican pediatric population S JimÊnez-Morales, R VelÂzquez-Cruz, JÂ RamÎrez-Bello, ... Human immunology 70 (4), 251-256, 2009 | 136 | 2009 |
Association of TLR7 copy number variation with susceptibility to childhood-onset systemic lupus erythematosus in Mexican population H García-Ortiz, R Velázquez-Cruz, F Espinosa-Rosales, ... Annals of the rheumatic diseases 69 (10), 1861-1865, 2010 | 130 | 2010 |
Evaluation of imputation-based association in and around the integrin-α-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant … S Han, X Kim-Howard, H Deshmukh, Y Kamatani, P Viswanathan, ... Human molecular genetics 18 (6), 1171-1180, 2009 | 125 | 2009 |
Author Correction: The mutational constraint spectrum quantified from variation in 141,456 humans KJ Karczewski, LC Francioli, G Tiao, BB Cummings, J Alföldi, Q Wang, ... Nature 590 (7846), E53-E53, 2021 | 102* | 2021 |
MiR‐146a polymorphism is associated with asthma but not with systemic lupus erythematosus and juvenile rheumatoid arthritis in Mexican patients S Jiménez‐Morales, R Gamboa‐Becerra, V Baca, BE Del Río‐Navarro, ... Tissue antigens 80 (4), 317-321, 2012 | 102 | 2012 |