Marc Poirot
Marc Poirot
Senior Scientist (directeur de recherche), INSERM
Verified email at - Homepage
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Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
Autophagy 12 (1), 1-222, 2016
Exosomes as new vesicular lipid transporters involved in cell–cell communication and various pathophysiologies
M Record, K Carayon, M Poirot, S Silvente-Poirot
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014
Exosomes as intercellular signalosomes and pharmacological effectors
M Record, C Subra, S Silvente-Poirot, M Poirot
Biochemical pharmacology 81 (10), 1171-1182, 2011
Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins
C Subra, D Grand, K Laulagnier, A Stella, G Lambeau, M Paillasse, ...
Journal of lipid research 51 (8), 2105-2120, 2010
Cholesterol and cancer, in the balance
S Silvente-Poirot, M Poirot
Science 343 (6178), 1445-1446, 2014
Tamoxifen and AEBS ligands induced apoptosis and autophagy in breast cancer cells through the stimulation of sterol accumulation
P De Medina, S Silvente-Poirot, M Poirot
Autophagy 5 (7), 1066-1067, 2009
Identification and pharmacological characterization of cholesterol-5, 6-epoxide hydrolase as a target for tamoxifen and AEBS ligands
P De Medina, MR Paillasse, G Segala, M Poirot, S Silvente-Poirot
Proceedings of the National Academy of Sciences 107 (30), 13520-13525, 2010
Dendrogenin A arises from cholesterol and histamine metabolism and shows cell differentiation and anti-tumour properties
P De Medina, MR Paillasse, G Segala, M Voisin, L Mhamdi, F Dalenc, ...
Nature communications 4 (1), 1-10, 2013
Tamoxifen is a potent inhibitor of cholesterol esterification and prevents the formation of foam cells
P de Medina, BL Payré, J Bernad, I Bosser, B Pipy, S Silvente-Poirot, ...
Journal of Pharmacology and Experimental Therapeutics 308 (3), 1165-1173, 2004
MAPK14/p38α confers irinotecan resistance to TP53-defective cells by inducing survival autophagy
S Paillas, A Causse, L Marzi, P De Medina, M Poirot, V Denis, ...
Autophagy 8 (7), 1098-1112, 2012
Synthesis and biological properties of new stilbene derivatives of resveratrol as new selective aryl hydrocarbon modulators
P De Medina, R Casper, JF Savouret, M Poirot
Journal of medicinal chemistry 48 (1), 287-291, 2005
Molecular characterization of the microsomal tamoxifen binding site
B Kedjouar, P de Médina, M Oulad-Abdelghani, B Payré, ...
Journal of Biological Chemistry 279 (32), 34048-34061, 2004
Ligands of the antiestrogen-binding site induce active cell death and autophagy in human breast cancer cells through the modulation of cholesterol metabolism
P De Medina, B Payré, N Boubekeur, J Bertrand-Michel, F Tercé, ...
Cell Death & Differentiation 16 (10), 1372-1384, 2009
Multiple targeting by the antitumor drug tamoxifen: a structure-activity study
P Medina, G Favre, M Poirot
Current Medicinal Chemistry-Anti-Cancer Agents 4 (6), 491-508, 2004
Signaling through cholesterol esterification: a new pathway for the cholecystokinin 2 receptor involved in cell growth and invasion
MR Paillasse, P De Medina, G Amouroux, L Mhamdi, M Poirot, ...
Journal of lipid research 50 (11), 2203-2211, 2009
Alteration of plasmalemmal caveolae mimics endothelial dysfunction observed in atheromatous rabbit aorta
B Darblade, D Caillaud, M Poirot, MJ Fouque, JC Thiers, J Rami, ...
Cardiovascular research 50 (3), 566-576, 2001
Cholesterol metabolism and cancer: the good, the bad and the ugly
S Silvente-Poirot, M Poirot
Current opinion in pharmacology 6 (12), 673-676, 2012
Synthesis of new alkylaminooxysterols with potent cell differentiating activities: identification of leads for the treatment of cancer and neurodegenerative diseases
P De Medina, MR Paillasse, B Payré, S Silvente-Poirot, M Poirot
Journal of medicinal chemistry 52 (23), 7765-7777, 2009
Cholesterol metabolites exported from human brain
L Iuliano, PJ Crick, C Zerbinati, L Tritapepe, J Abdel-Khalik, M Poirot, ...
Steroids 99, 189-193, 2015
Cholesterol-5, 6-epoxides: Chemistry, biochemistry, metabolic fate and cancer
M Poirot, S Silvente-Poirot
Biochimie 95 (3), 622-31, 2013
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