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David Rubinsztein
David Rubinsztein
Verified email at cam.ac.uk - Homepage
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Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13283*2021
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ...
Cell Death & Differentiation 25 (3), 486-541, 2018
56392018
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ...
Nature genetics 45 (12), 1452-1458, 2013
44272013
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
D Harold, R Abraham, P Hollingworth, R Sims, A Gerrish, ML Hamshere, ...
Nature genetics 41 (10), 1088-1093, 2009
33342009
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
L Galluzzi, I Vitale, JM Abrams, ES Alnemri, EH Baehrecke, ...
Cell Death & Differentiation 19 (1), 107-120, 2012
31672012
TFEB links autophagy to lysosomal biogenesis
C Settembre, C Di Malta, VA Polito, MG Arencibia, F Vetrini, S Erdin, ...
science 332 (6036), 1429-1433, 2011
30612011
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
B Ravikumar, C Vacher, Z Berger, JE Davies, S Luo, LG Oroz, F Scaravilli, ...
Nature genetics 36 (6), 585-595, 2004
28192004
Autophagy and aging
DC Rubinsztein, G Mariņo, G Kroemer
Cell 146 (5), 682-695, 2011
24732011
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nature genetics 51 (3), 414-430, 2019
22952019
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
P Hollingworth, D Harold, R Sims, A Gerrish, JC Lambert, ...
Nature genetics 43 (5), 429-435, 2011
22032011
Regulation of mammalian autophagy in physiology and pathophysiology
B Ravikumar, S Sarkar, JE Davies, M Futter, M Garcia-Arencibia, ...
Physiological reviews 90 (4), 1383-1435, 2010
20922010
The roles of intracellular protein-degradation pathways in neurodegeneration
DC Rubinsztein
Nature 443 (7113), 780-786, 2006
20552006
α-Synuclein is degraded by both autophagy and the proteasome
JL Webb, B Ravikumar, J Atkins, JN Skepper, DC Rubinsztein
Journal of Biological Chemistry 278 (27), 25009-25013, 2003
17662003
Autophagy modulation as a potential therapeutic target for diverse diseases
DC Rubinsztein, P Codogno, B Levine
Nature reviews Drug discovery 11 (9), 709-730, 2012
16152012
Molecular definitions of autophagy and related processes
L Galluzzi, EH Baehrecke, A Ballabio, P Boya, JM Bravo‐San Pedro, ...
The EMBO journal 36 (13), 1811-1836, 2017
15872017
Analysis of shared heritability in common disorders of the brain
Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ...
Science 360 (6395), eaap8757, 2018
13802018
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
B Ravikumar, R Duden, DC Rubinsztein
Human molecular genetics 11 (9), 1107-1117, 2002
13532002
Autophagy in malignant transformation and cancer progression
L Galluzzi, F Pietrocola, JM Bravo‐San Pedro, RK Amaravadi, ...
The EMBO journal 34 (7), 856-880, 2015
12582015
Potential therapeutic applications of autophagy
DC Rubinsztein, JE Gestwicki, LO Murphy, DJ Klionsky
Nature reviews Drug discovery 6 (4), 304-312, 2007
12512007
Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and α-synuclein
S Sarkar, JE Davies, Z Huang, A Tunnacliffe, DC Rubinsztein
Journal of Biological Chemistry 282 (8), 5641-5652, 2007
12462007
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Articles 1–20