Fluorescent drug-loaded, polymeric-based, branched gold nanoshells for localized multimodal therapy and imaging of tumoral cells A Topete, M Alatorre-Meda, P Iglesias, EM Villar-Alvarez, S Barbosa, ... ACS nano 8 (3), 2725-2738, 2014 | 190 | 2014 |
A novel BRET-based genetically encoded biosensor for functional imaging of hypoxia P Iglesias, JA Costoya Biosensors and Bioelectronics 24 (10), 3126-3130, 2009 | 41 | 2009 |
Retinoblastoma Loss Modulates DNA Damage Response Favoring Tumor Progression M Seoane, P Iglesias, T Gonzalez, F Dominguez, M Fraga, C Aliste, ... PLoS ONE 3 (11), e3632, 2008 | 39 | 2008 |
NIR-light active hybrid nanoparticles for combined imaging and bimodal therapy of cancerous cells A Topete, D Melgar, M Alatorre-Meda, P Iglesias, B Argibay, S Vidawati, ... Journal of Materials Chemistry B 2 (40), 6967-6977, 2014 | 25 | 2014 |
Lineage-specific control of TFIIH by MITF determines transcriptional homeostasis and DNA repair M Seoane, S Buhs, P Iglesias, J Strauss, AC Puller, J Müller, H Gerull, ... Oncogene 38 (19), 3616-3635, 2019 | 22 | 2019 |
A Bio-inspired Hypoxia Sensor using HIF1a-Oxygen-Dependent Degradation Domain. P Iglesias, C Penas, L Barral-Cagiao, E Pazos, JA Costoya Scientific Reports 9 (1), 7177, 2019 | 13 | 2019 |
Defining hypoxic microenvironments by non-invasive functional optical imaging P Iglesias, M Fraga, JA Costoya European Journal of Cancer 49 (1), 264-271, 2013 | 8 | 2013 |
The antimitotic potential of PARP inhibitors, an unexplored therapeutic alternative P Iglesias, J A Costoya Current topics in medicinal chemistry 14 (20), 2346-2365, 2014 | 7 | 2014 |
PARP1 Deficiency Reduces Tumour Growth by Decreasing E2F1 Hyperactivation: A Novel Mechanism in the Treatment of Cancer P Iglesias, M Seoane, I Golán, I Castro-Piedras, M Fraga, VM Arce, ... Cancers 12 (10), 2907, 2020 | 6 | 2020 |
The maintenance of mitochondrial genetic stability is crucial during the oncogenic process P Iglesias, A Salas, JA Costoya Communicative & integrative biology 5 (1), 34-38, 2012 | 6 | 2012 |
Development of a biosensor based on a new marine luciferase fused to an affibody to assess Her2 expression in living cells LR de la Fuente, IG Cancela, ÁM Estévez-Salguero, P Iglesias, ... Analytica Chimica Acta, 340084, 2022 | 3 | 2022 |
PARP-1 regulates cell cycle by downregulating E2F-1 transcriptional activity in vitro and in vivo P Iglesias, M Seoane, I Castro-Piedras, VM Arce, JA Costoya Cancer Research 76 (14 Supplement), 2893-2893, 2016 | 1 | 2016 |
AI is a viable alternative to high throughput screening: a 318-target study Scientific Reports 14 (1), 7526, 2024 | | 2024 |
Shedding light on PARP1-E2F1 interaction by Cryo-EM P Iglesias, E Casajus-Pelegay, M Moreno-Morcillo, L González-Rendo, ... Cancer Research 84 (6_Supplement), 5785-5785, 2024 | | 2024 |
New drug development opportunities for PARP1 P Iglesias, D Moreiras, L Porres-Ventin, L Gonzalez-Rendo, JA Zumalave, ... Cancer Research 84 (6_Supplement), 4483-4483, 2024 | | 2024 |
A New Opportunity for “Old” Molecules: Targeting PARP1 Activity through a Non-Enzymatic Mechanism P Iglesias, M Seoane, I Golán-Cancela, M Fraga, VM Arce, JA Costoya International Journal of Molecular Sciences 24 (10), 8849, 2023 | | 2023 |
PARP1: New Drug Development Opportunities for an Old Target P Iglesias, M Seoane, I Golán-Cancela, M Fraga, VM Arce, JA Costoya Preprints, 2023 | | 2023 |
Genome-wide interference of ZNF423 with B-lineage transcriptional circuitries in acute lymphoblastic leukemia P Iglesias, AC Puller, M Seoane, M Spohn, S Raasch, M Klokow, J Müller, ... Blood Advances 5 (5), 1209, 2021 | | 2021 |
PARP-1 como regulador del ciclo celular P Iglesias Vázquez | | 2015 |
Functional Optical Imaging-based Biosensors: Pablo Iglesias and Jose A. Costoya P Iglesias, JA Costoya Biosensors and Cancer, 19-35, 2012 | | 2012 |