Chimeric antigen receptor T cells for sustained remissions in leukemia SL Maude, N Frey, PA Shaw, R Aplenc, DM Barrett, NJ Bunin, A Chew, ... New England Journal of Medicine 371 (16), 1507-1517, 2014 | 3526 | 2014 |
Chimeric antigen receptor–modified T cells in chronic lymphoid leukemia DL Porter, BL Levine, M Kalos, A Bagg, CH June N engl j Med 365, 725-733, 2011 | 3214 | 2011 |
Chimeric antigen receptor–modified T cells for acute lymphoid leukemia SA Grupp, M Kalos, D Barrett, R Aplenc, DL Porter, SR Rheingold, ... New England Journal of Medicine 368 (16), 1509-1518, 2013 | 2820 | 2013 |
T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia M Kalos, BL Levine, DL Porter, S Katz, SA Grupp, A Bagg, CH June Science translational medicine 3 (95), 95ra73-95ra73, 2011 | 2278 | 2011 |
The B7 and CD28 receptor families CH June, JA Bluestone, LM Nadler, CB Thompson Immunology today 15 (7), 321-331, 1994 | 1643 | 1994 |
Tisagenlecleucel in children and young adults with B-cell lymphoblastic leukemia SL Maude, TW Laetsch, J Buechner, S Rives, M Boyer, H Bittencourt, ... New England Journal of Medicine 378 (5), 439-448, 2018 | 1614 | 2018 |
CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL LH Boise, AJ Minn, PJ Noel, CH June, MA Accavitti, T Lindsten, ... Immunity 3 (1), 87-98, 1995 | 1455 | 1995 |
Regulatory CD4+ CD25+ T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer EY Woo, CS Chu, TJ Goletz, K Schlienger, H Yeh, G Coukos, SC Rubin, ... Cancer research 61 (12), 4766-4772, 2001 | 1442 | 2001 |
A human memory T cell subset with stem cell–like properties L Gattinoni, E Lugli, Y Ji, Z Pos, CM Paulos, MF Quigley, JR Almeida, ... Nature medicine 17 (10), 1290-1297, 2011 | 1312 | 2011 |
Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV P Tebas, D Stein, WW Tang, I Frank, SQ Wang, G Lee, SK Spratt, ... New England Journal of Medicine 370 (10), 901-910, 2014 | 1265 | 2014 |
Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases EE Perez, J Wang, JC Miller, Y Jouvenot, KA Kim, O Liu, N Wang, G Lee, ... Nature biotechnology 26 (7), 808-816, 2008 | 1162 | 2008 |
The CD28 signaling pathway regulates glucose metabolism KA Frauwirth, JL Riley, MH Harris, RV Parry, JC Rathmell, DR Plas, ... Immunity 16 (6), 769-777, 2002 | 1078 | 2002 |
Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia DL Porter, WT Hwang, NV Frey, SF Lacey, PA Shaw, AW Loren, A Bagg, ... Science translational medicine 7 (303), 303ra139-303ra139, 2015 | 1059 | 2015 |
SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T … JM Chemnitz, RV Parry, KE Nichols, CH June, JL Riley The Journal of Immunology 173 (2), 945-954, 2004 | 1055 | 2004 |
Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway T Lindstein, CH June, JA Ledbetter, G Stella, CB Thompson Science 244 (4902), 339-343, 1989 | 1051 | 1989 |
Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics CG Brunstein, JS Miller, Q Cao, DH McKenna, KL Hippen, J Curtsinger, ... Blood, The Journal of the American Society of Hematology 117 (3), 1061-1070, 2011 | 974 | 2011 |
Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo MC Milone, JD Fish, C Carpenito, RG Carroll, GK Binder, D Teachey, ... Molecular therapy 17 (8), 1453-1464, 2009 | 952 | 2009 |
Cutting edge: regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation EY Woo, H Yeh, CS Chu, K Schlienger, RG Carroll, JL Riley, LR Kaiser, ... The Journal of Immunology 168 (9), 4272-4276, 2002 | 893 | 2002 |
Role of the CD28 receptor in T-cell activation CH June, JA Ledbetter, PS Linsley, CB Thompson Elsevier, 1990 | 849 | 1990 |
CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines CB Thompson, T Lindsten, JA Ledbetter, SL Kunkel, HA Young, ... Proceedings of the National Academy of Sciences 86 (4), 1333-1337, 1989 | 832 | 1989 |