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DL Porter, BL Levine, M Kalos, A Bagg, CH June
New England Journal of Medicine 365 (8), 725-733, 2011
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SL Maude, N Frey, PA Shaw, R Aplenc, DM Barrett, NJ Bunin, A Chew, ...
New England Journal of Medicine 371 (16), 1507-1517, 2014
|Chimeric antigen receptor–modified T cells for acute lymphoid leukemia|
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New England Journal of Medicine 368 (16), 1509-1518, 2013
|T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia|
M Kalos, BL Levine, DL Porter, S Katz, SA Grupp, A Bagg, CH June
Science translational medicine 3 (95), 95ra73-95ra73, 2011
|The B7 and CD28 receptor families|
CH June, JA Bluestone, LM Nadler, CB Thompson
Immunology today 15 (7), 321-331, 1994
|Regulatory CD4+ CD25+ T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer|
EY Woo, CS Chu, TJ Goletz, K Schlienger, H Yeh, G Coukos, SC Rubin, ...
Cancer research 61 (12), 4766-4772, 2001
|CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL|
LH Boise, AJ Minn, PJ Noel, CH June, MA Accavitti, T Lindsten, ...
Immunity 3 (1), 87-98, 1995
|Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV|
P Tebas, D Stein, WW Tang, I Frank, SQ Wang, G Lee, SK Spratt, ...
New England Journal of Medicine 370 (10), 901-910, 2014
|Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases|
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Nature biotechnology 26 (7), 808, 2008
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Nature medicine 17 (10), 1290, 2011
|Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway|
T Lindstein, CH June, JA Ledbetter, G Stella, CB Thompson
Science 244 (4902), 339-343, 1989
|The CD28 signaling pathway regulates glucose metabolism|
KA Frauwirth, JL Riley, MH Harris, RV Parry, JC Rathmell, DR Plas, ...
Immunity 16 (6), 769-777, 2002
|SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T …|
JM Chemnitz, RV Parry, KE Nichols, CH June, JL Riley
The Journal of Immunology 173 (2), 945-954, 2004
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CG Brunstein, JS Miller, Q Cao, DH McKenna, KL Hippen, J Curtsinger, ...
Blood 117 (3), 1061-1070, 2011
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EY Woo, H Yeh, CS Chu, K Schlienger, RG Carroll, JL Riley, LR Kaiser, ...
The Journal of Immunology 168 (9), 4272-4276, 2002
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CH June, JA Ledbetter, PS Linsley, CB Thompson
Immunology today 11, 211-216, 1990
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Proceedings of the National Academy of Sciences 86 (4), 1333-1337, 1989
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Molecular Therapy 17 (8), 1453-1464, 2009
|Tisagenlecleucel in children and young adults with B-cell lymphoblastic leukemia|
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New England Journal of Medicine 378 (5), 439-448, 2018
|Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia|
DL Porter, WT Hwang, NV Frey, SF Lacey, PA Shaw, AW Loren, A Bagg, ...
Science translational medicine 7 (303), 303ra139-303ra139, 2015