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Martyn Sharpe
Martyn Sharpe
The Methodist Hospital
Dirección de correo verificada de houstonmethodist.org
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β‐Amyloid inhibits integrated mitochondrial respiration and key enzyme activities
CS Casley, L Canevari, JM Land, JB Clark, MA Sharpe
Journal of neurochemistry 80 (1), 91-100, 2002
6002002
β-Amyloid fragment 25–35 causes mitochondrial dysfunction in primary cortical neurons
CS Casley, JM Land, MA Sharpe, JB Clark, MR Duchen, L Canevari
Neurobiology of disease 10 (3), 258-267, 2002
2542002
Reactions of nitric oxide with mitochondrial cytochrome c: a novel mechanism for the formation of nitroxyl anion and peroxynitrite
MA Sharpe, CE Cooper
Biochemical Journal 332 (1), 9-19, 1998
2441998
Oxidation of nitric oxide by oxomanganese–salen complexes: a new mechanism for cellular protection by superoxide dismutase/catalase mimetics
MA Sharpe, R Ollosson, VC Stewart, JB Clark
Biochemical Journal 366 (1), 97-107, 2002
1992002
Superoxide dismutase mimetics elevate superoxide dismutase activity in vivo but do not retard aging in the nematode Caenorhabditis elegans
M Keaney, F Matthijssens, M Sharpe, J Vanfleteren, D Gems
Free Radical Biology and Medicine 37 (2), 239-250, 2004
1942004
Interaction of Peroxynitrite with Mitochondrial Cytochrome Oxidase: Catalytic Production of Nitric Oxide and Irreversible Inhibition of Enzyme Activity
MA Sharpe, CE Cooper
Journal of Biological Chemistry 273 (47), 30961-30972, 1998
1831998
Astrocyte‐derived nitric oxide causes both reversible and irreversible damage to the neuronal mitochondrial respiratory chain
VC Stewart, MA Sharpe, JB Clark, SJR Heales
Journal of neurochemistry 75 (2), 694-700, 2000
1762000
Fibrillar beta-amyloid peptide Aβ1–40 activates microglial proliferation via stimulating TNF-α release and H2O2 derived from NADPH oxidase: a cell culture study
A Jekabsone, PK Mander, A Tickler, M Sharpe, GC Brown
Journal of neuroinflammation 3, 1-13, 2006
1642006
Regulation of the pentose phosphate pathway by an androgen receptor–mTOR-mediated mechanism and its role in prostate cancer cell growth
E Tsouko, AS Khan, MA White, JJ Han, Y Shi, FA Merchant, MA Sharpe, ...
Oncogenesis 3 (5), e103-e103, 2014
1602014
Cytochrome c oxidase rapidly metabolises nitric oxide to nitrite
J Torres, MA Sharpe, A Rosquist, CE Cooper, MT Wilson
FEBS letters 475 (3), 263-266, 2000
1312000
Nitric oxide ejects electrons from the binuclear centre of cytochrome c oxidase by reacting with oxidised copper: a general mechanism for the interaction of copper proteins …
CE Cooper, J Torres, MA Sharpe, MT Wilson
FEBS letters 414 (2), 281-284, 1997
1211997
Toxicity of myoglobin and haemoglobin: oxidative stress in patients with rhabdomyolysis and subarachnoid haemorrhage
BJ Reeder, MA Sharpe, AD Kay, M Kerr, K Moore, MT Wilson
Biochemical Society Transactions 30 (4), 745-748, 2002
1182002
Nitric oxide and peroxynitrite cause irreversible increases in the Km for oxygen of mitochondrial cytochrome oxidase: in vitro and in vivo studies
CE Cooper, NA Davies, M Psychoulis, L Canevari, TE Bates, MS Dobbie, ...
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1607 (1), 27-34, 2003
972003
Characteristics and mechanism of formation of peroxide-induced heme to protein cross-linking in myoglobin
BJ Reeder, DA Svistunenko, MA Sharpe, MT Wilson
Biochemistry 41 (1), 367-375, 2002
952002
Storage of an Excess Proton in the Hydrogen-Bonded Network of the D-Pathway of Cytochrome c Oxidase:  Identification of a Protonated Water Cluster
J Xu, MA Sharpe, L Qin, S Ferguson-Miller, GA Voth
Journal of the American Chemical Society 129 (10), 2910-2913, 2007
892007
Lipotoxicity in renal proximal tubular cells: relationship between endoplasmic reticulum stress and oxidative stress pathways
E Katsoulieris, JG Mabley, M Samai, MA Sharpe, IC Green, PK Chatterjee
Free Radical Biology and Medicine 48 (12), 1654-1662, 2010
842010
A chemically explicit model for the mechanism of proton pumping in heme–copper oxidases
MA Sharpe, S Ferguson-Miller
Journal of bioenergetics and biomembranes 40, 541-549, 2008
842008
Nitric oxide and Fenton/Haber–Weiss chemistry: nitric oxide is a potent antioxidant at physiological concentrations
MA Sharpe, SJ Robb, JB Clark
Journal of neurochemistry 87 (2), 386-394, 2003
832003
Cytochrome c release from rat brain mitochondria is proportional to the mitochondrial functional deficit: implications for apoptosis and neurodegenerative disease
R Clayton, JB Clark, M Sharpe
Journal of neurochemistry 92 (4), 840-849, 2005
782005
Superoxide dismutase mimetics with catalase activity reduce the organ injury in hemorrhagic shock
M Izumi, MC McDonald, MA Sharpe, PK Chatterjee, C Thiemermann
Shock 18 (3), 230-235, 2002
782002
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Artículos 1–20