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Kanaga Sabapathy
Kanaga Sabapathy
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Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation
K Sabapathy, K Hochedlinger, SY Nam, A Bauer, M Karin, EF Wagner
Molecular cell 15 (5), 713-725, 2004
4752004
Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2
K Sabapathy, W Jochum, K Hochedlinger, L Chang, M Karin, EF Wagner
Mechanisms of development 89 (1-2), 115-124, 1999
4601999
Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than others
K Sabapathy, DP Lane
Nature reviews Clinical oncology 15 (1), 13-30, 2018
4162018
JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development
K Sabapathy, Y Hu, T Kallunki, M Schreiber, JP David, W Jochum, ...
Current biology 9 (3), 116-125, 1999
3981999
JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and-independent mechanisms
JP David, K Sabapathy, O Hoffmann, MH Idarraga, EF Wagner
Journal of cell science 115 (22), 4317-4325, 2002
3942002
C-Jun Nh2-Terminal Kinase (Jnk)1 and Jnk2 Have Similar and Stage-Dependent Roles in Regulating T Cell Apoptosis and Proliferation
K Sabapathy, T Kallunki, JP David, I Graef, M Karin, EF Wagner
The Journal of experimental medicine 193 (3), 317-328, 2001
2802001
c-Jun promotes cellular survival by suppression of PTEN
K Hettinger, F Vikhanskaya, MK Poh, MK Lee, I De Belle, JT Zhang, ...
Cell Death & Differentiation 14 (2), 218-229, 2007
2102007
Functional crosstalk between type I and II interferon through the regulated expression of STAT1
DJ Gough, NL Messina, L Hii, JA Gould, K Sabapathy, APS Robertson, ...
PLoS biology 8 (4), e1000361, 2010
1952010
An apoptotic signaling pathway in the interferon antiviral response mediated by RNase L and c-Jun NH2-terminal kinase
G Li, Y Xiang, K Sabapathy, RH Silverman
Journal of Biological Chemistry 279 (2), 1123-1131, 2004
1902004
Regulation of ES cell differentiation by functional and conformational modulation of p53
K Sabapathy, M Klemm, R Jaenisch, EF Wagner
The EMBO journal, 1997
1891997
Role of the JNK pathway in human diseases
K Sabapathy
Progress in molecular biology and translational science 106, 145-169, 2012
1822012
Cancer-derived p53 mutants suppress p53-target gene expression—potential mechanism for gain of function of mutant p53
F Vikhanskaya, MK Lee, M Mazzoletti, M Broggini, K Sabapathy
Nucleic acids research 35 (6), 2093-2104, 2007
1772007
Trp53-dependent DNA-repair is affected by the codon 72 polymorphism
M Siddique, K Sabapathy
Oncogene 25 (25), 3489-3500, 2006
1692006
Differential effects of JNK1 and JNK2 on signal specific induction of apoptosis
K Hochedlinger, EF Wagner, K Sabapathy
Oncogene 21 (15), 2441-2445, 2002
1332002
Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors
MN Huang, W Yu, WW Teoh, M Ardin, A Jusakul, AWT Ng, A Boot, ...
Genome research 27 (9), 1475-1486, 2017
1132017
JNK2: a negative regulator of cellular proliferation
K Sabapathy, EF Wagner
Cell Cycle 3 (12), 1520-1523, 2004
1112004
Jun N-terminal kinase 2 modulates thymocyte apoptosis and T cell activation through c-Jun and nuclear factor of activated T cell (NF-AT)
A Behrens, K Sabapathy, I Graef, M Cleary, GR Crabtree, EF Wagner
Proceedings of the National Academy of Sciences 98 (4), 1769-1774, 2001
1102001
Understanding p53 functions through p53 antibodies
K Sabapathy, DP Lane
Journal of molecular cell biology 11 (4), 317-329, 2019
1062019
c-Jun regulates the stability and activity of the p53 homologue, p73
WH Toh, MM Siddique, L Boominathan, KW Lin, K Sabapathy
Journal of Biological Chemistry 279 (43), 44713-44722, 2004
992004
Evidence for selective expression of the p53 codon 72 polymorphs: implications in cancer development
MM Siddique, C Balram, L Fiszer-Maliszewska, A Aggarwal, A Tan, P Tan, ...
Cancer Epidemiology Biomarkers & Prevention 14 (9), 2245-2252, 2005
962005
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