Design of a long-acting follitropin agonist by fusing the C-terminal sequence of the chorionic gonadotropin beta subunit to the follitropin beta subunit. FA Fares, N Suganuma, K Nishimori, PS LaPolt, AJ Hsueh, I Boime Proceedings of the National Academy of Sciences 89 (10), 4304-4308, 1992 | 349 | 1992 |
Expression of biologically active human follitropin in Chinese hamster ovary cells JL Keene, MM Matzuk, T Otani, BC Fauser, AB Galway, AJ Hsueh, ... Journal of Biological Chemistry 264 (9), 4769-4775, 1989 | 297 | 1989 |
Site specificity of the chorionic gonadotropin N-linked oligosaccharides in signal transduction MM Matzuk, JL Keene, I Boime Journal of Biological Chemistry 264 (5), 2409-2414, 1989 | 275 | 1989 |
A single gonadotropin alpha-subunit gene in normal tissue and tumor-derived cell lines. M Boothby, RW Ruddon, C Anderson, D McWilliams, I Boime Journal of Biological Chemistry 256 (10), 5121-5127, 1981 | 265 | 1981 |
The role of the asparagine-linked oligosaccharides of the alpha subunit in the secretion and assembly of human chorionic gonadotrophin. MM Matzuk, I Boime The Journal of cell biology 106 (4), 1049-1059, 1988 | 252 | 1988 |
The biological role of the carboxyl-terminal extension of human chorionic gonadotroin β-subunit MM Matzuk, AJW Hsueh, P Lapolt, A Tsafriri, JL Keene, I Boime Endocrinology 126 (1), 376-383, 1990 | 244 | 1990 |
Transgenic models to study gonadotropin function: the role of follicle-stimulating hormone in gonadal growth and tumorigenesis TR Kumar, G Palapattu, P Wang, TK Woodruff, I Boime, MC Byrne, ... Molecular endocrinology 13 (6), 851-865, 1999 | 215 | 1999 |
Cytological localization of chorionic gonadotropin alpha and placental lactogen mRNAs during development of the human placenta. M Hoshina, M Boothby, I Boime The Journal of cell biology 93 (1), 190-198, 1982 | 213 | 1982 |
Identification of the transcriptionally active genes of the chorionic gonadotropin beta gene cluster in vivo. M Bo, I Boime Journal of Biological Chemistry 267 (5), 3179-3184, 1992 | 201 | 1992 |
The beta subunit of human chorionic gonadotropin is encoded by multiple genes. P Policastro, CE Ovitt, M Hoshina, H Fukuoka, MR Boothby, I Boime Journal of Biological Chemistry 258 (19), 11492-11499, 1983 | 190 | 1983 |
Advances in recombinant DNA technology: corifollitropin alfa, a hybrid molecule with sustained follicle-stimulating activity and reduced injection frequency B Fauser, B Mannaerts, P Devroey, A Leader, I Boime, DT Baird Human Reproduction Update 15 (3), 309-321, 2009 | 188 | 2009 |
Expression of human luteinizing hormone (LH) receptor: interaction with LH and chorionic gonadotropin from human but not equine, rat, and ovine species XC Jia, M Oikawa, M Bo, T Tanaka, T Ny, I Boime, AJW Hsueh Molecular Endocrinology 5 (6), 759-768, 1991 | 171 | 1991 |
Structural elucidation of the disulfated oligosaccharide from bovine lutropin. ED Green, H Van Halbeek, I Boime, JU Baenziger Journal of Biological Chemistry 260 (29), 15623-15630, 1985 | 171 | 1985 |
Protein synthesis directed by encephalomyocarditis virus RNA: properties of a transfer RNA-dependent system H Aviv, I Boime, P Leder Proceedings of the National Academy of Sciences 68 (9), 2303-2307, 1971 | 166 | 1971 |
A map of the hCG beta-LH beta gene cluster. PF Policastro, S Daniels-McQueen, G Carle, I Boime Journal of Biological Chemistry 261 (13), 5907-5916, 1986 | 158 | 1986 |
mRNA-dependent synthesis of authentic precursor to human placental lactogen: conversion to its mature hormone form in ascites cell-free extracts. E Szczesna, I Boime Proceedings of the National Academy of Sciences 73 (4), 1179-1183, 1976 | 149 | 1976 |
Linkage of human chorionic gonadotrophin and placental lactogen biosynthesis to trophoblast differentiation and tumorigenesis M Hoshina, M Boothby, R Hussa, R Pattillo, HM Camel, I Boime Placenta 6 (2), 163-172, 1985 | 145 | 1985 |
In Vitro and in Vivo Bioactivity of Recombinant Human Follicle-Stimulating Hormone and Partially Deglycosylated Variants Secreted by Transfected Eukaryotic Cell … AB Galway, AJW Hsueh, JL Keene, M Yamoto, B Fauser, I Boime Endocrinology 127 (1), 93-100, 1990 | 141 | 1990 |
Granulosa cells as hormone targets: the role of biologically active follicle-stimulating hormone in reproduction AJW Hsueh, TA Bicsak, XC Jia, KD Dahl, BCJM Fauser, AB Galway, ... Proceedings of the 1988 Laurentian Hormone Conference, 209-277, 1989 | 140 | 1989 |
Biosynthesis of a biologically active single peptide chain containing the human common alpha and chorionic gonadotropin beta subunits in tandem. T Sugahara, MR Pixley, S Minami, E Perlas, D Ben-Menahem, AJ Hsueh, ... Proceedings of the National Academy of Sciences 92 (6), 2041-2045, 1995 | 138 | 1995 |