| PI 3‐kinase is a dual specificity enzyme: autoregulation by an intrinsic protein‐serine kinase activity. R Dhand, I Hiles, G Panayotou, S Roche, MJ Fry, I Gout, NF Totty, ... The EMBO journal 13 (3), 522-533, 1994 | 608 | 1994 |
| The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors. S Roche, M Koegl, SA Courtneidge Proceedings of the National Academy of Sciences 91 (19), 9185-9189, 1994 | 354 | 1994 |
| Requirement for Src family protein tyrosine kinases in G2 for fibroblast cell division S Roche, S Fumagalli, SA Courtneidge Science 269 (5230), 1567-1569, 1995 | 343 | 1995 |
| DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases S Roche, M Koegl, MV Barone, MF Roussel, SA Courtneidge Molecular and cellular biology 15 (2), 1102-1109, 1995 | 291 | 1995 |
| Evidence that resistance to nilotinib may be due to BCR-ABL, Pgp, or Src kinase overexpression FX Mahon, S Hayette, V Lagarde, F Belloc, B Turcq, F Nicolini, ... Cancer research 68 (23), 9809-9816, 2008 | 275 | 2008 |
| A specific function for phosphatidylinositol 3-kinase α (p85α-p110α) in cell survival and for phosphatidylinositol 3-kinase β (p85α-p110β) in de novo DNA synthesis of human … C Bénistant, H Chapuis, S Roche Oncogene 19 (44), 5083-5090, 2000 | 212 | 2000 |
| Cytoplasmic signalling by the c‐Abl tyrosine kinase in normal and cancer cells A Sirvent, C Benistant, S Roche Biology of the Cell 100 (11), 617-631, 2008 | 199 | 2008 |
| A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor A Yart, M Laffargue, P Mayeux, S Chretien, C Peres, N Tonks, S Roche, ... Journal of Biological Chemistry 276 (12), 8856-8864, 2001 | 196 | 2001 |
| A function for phosphatidylinositol 3-kinase β (p85α-p110β) in fibroblasts during mitogenesis: requirement for insulin-and lysophosphatidic acid-mediated signal transduction S Roche, J Downward, P Raynal, SA Courtneidge Molecular and cellular biology 18 (12), 7119-7129, 1998 | 177 | 1998 |
| Src and Ras are involved in separate pathways in epithelial cell scattering B Boyer, S Roche, M Denoyelle, JP Thiery The EMBO journal 16 (19), 5904-5913, 1997 | 176 | 1997 |
| c‐Abl is an effector of Src for growth factor‐induced c‐myc expression and DNA synthesis O Furstoss, K Dorey, V Simon, D Barilà, G Superti‐Furga, S Roche The EMBO journal, 2002 | 167 | 2002 |
| Calcium release at fertilization in starfish eggs is mediated by phospholipase Cγ DJ Carroll, CS Ramarao, LM Mehlmann, S Roche, M Terasaki, LA Jaffe The Journal of cell biology 138 (6), 1303-1311, 1997 | 167 | 1997 |
| Requirement of phospholipase C gamma, the tyrosine phosphatase Syp and the adaptor proteins Shc and Nck for PDGF‐induced DNA synthesis: evidence for the existence of Ras … S Roche, J McGlade, M Jones, GD Gish, T Pawson, SA Courtneidge The EMBO Journal 15 (18), 4940-4948, 1996 | 160 | 1996 |
| Identification of a novel immunoreceptor tyrosine-based activation motif-containing molecule, STAM2, by mass spectrometry and its involvement in growth factor and cytokine … A Pandey, MM Fernandez, H Steen, B Blagoev, MM Nielsen, S Roche, ... Journal of Biological Chemistry 275 (49), 38633-38639, 2000 | 146 | 2000 |
| Syntenin mediates SRC function in exosomal cell-to-cell communication NS Imjeti, K Menck, AL Egea-Jimenez, C Lecointre, F Lembo, ... Proceedings of the National Academy of Sciences 114 (47), 12495-12500, 2017 | 136 | 2017 |
| Quantitative phosphoproteomics reveals a cluster of tyrosine kinases that mediates SRC invasive activity in advanced colon carcinoma cells C Leroy, C Fialin, A Sirvent, V Simon, S Urbach, J Poncet, B Robert, ... Cancer research 69 (6), 2279-2286, 2009 | 131 | 2009 |
| Quantitative phosphoproteomics revealed interplay between Syk and Lyn in the resistance to nilotinib in chronic myeloid leukemia cells R Gioia, C Leroy, C Drullion, V Lagarde, G Etienne, S Dulucq, E Lippert, ... Blood, The Journal of the American Society of Hematology 118 (8), 2211-2221, 2011 | 124 | 2011 |
| An epidermal growth factor receptor/Gab1 signaling pathway is required for activation of phosphoinositide 3-kinase by lysophosphatidic acid M Laffargue, P Raynal, A Yart, C Peres, R Wetzker, S Roche, B Payrastre, ... Journal of Biological Chemistry 274 (46), 32835-32841, 1999 | 116 | 1999 |
| Nucleophosmin-anaplastic lymphoma kinase of anaplastic large-cell lymphoma recruits, activates, and uses pp60c-src to mediate its mitogenicity D Cussac, C Greenland, S Roche, RY Bai, J Duyster, SW Morris, G Delsol, ... Blood 103 (4), 1464-1471, 2004 | 115 | 2004 |
| A function for phosphoinositide 3-kinase β lipid products in coupling βγ to Ras activation in response to lysophosphatidic acid A Yart, S Roche, R Wetzker, M Laffargue, N Tonks, P Mayeux, H Chap, ... Journal of Biological Chemistry 277 (24), 21167-21178, 2002 | 115 | 2002 |
