Cancer immunotherapy with immunomodulatory anti-CD137 and anti–PD-1 monoclonal antibodies requires BATF3-dependent dendritic cells AR Sánchez-Paulete, FJ Cueto, M Martínez-López, S Labiano, ... Cancer discovery 6 (1), 71-79, 2016 | 439 | 2016 |
Tumor-produced interleukin-8 attracts human myeloid-derived suppressor cells and elicits extrusion of neutrophil extracellular traps (NETs) C Alfaro, A Teijeira, C Oñate, G Perez, MF Sanmamed, MP Andueza, ... Clinical Cancer Research 22 (15), 3924-3936, 2016 | 362 | 2016 |
Antigen cross-presentation and T-cell cross-priming in cancer immunology and immunotherapy AR Sánchez-Paulete, A Teijeira, FJ Cueto, S Garasa, JL Pérez-Gracia, ... Annals of Oncology 28, xii44-xii55, 2017 | 259 | 2017 |
Agonists of co-stimulation in cancer immunotherapy directed against CD137, OX40, GITR, CD27, CD28, and ICOS MF Sanmamed, F Pastor, A Rodriguez, JL Perez-Gracia, ... Seminars in oncology 42 (4), 640-655, 2015 | 255 | 2015 |
Abscopal effects of radiotherapy are enhanced by combined immunostimulatory mAbs and are dependent on CD8 T cells and crosspriming ME Rodriguez-Ruiz, I Rodriguez, S Garasa, B Barbes, JL Solorzano, ... Cancer research 76 (20), 5994-6005, 2016 | 221 | 2016 |
Intratumoral delivery of immunotherapy—act locally, think globally MA Aznar, N Tinari, AJ Rullán, AR Sánchez-Paulete, ME Rodriguez-Ruiz, ... The Journal of Immunology 198 (1), 31-39, 2017 | 216 | 2017 |
PD-L1/PD-1 presence in the tumor microenvironment and activity of PD-1 blockade in multiple myeloma B Paiva, A Azpilikueta, N Puig, EM Ocio, R Sharma, BO Oyajobi, ... Leukemia 29 (10), 2110-2113, 2015 | 199 | 2015 |
Deciphering CD137 (4‐1BB) signaling in T‐cell costimulation for translation into successful cancer immunotherapy AR Sanchez‐Paulete, S Labiano, ME Rodriguez‐Ruiz, A Azpilikueta, ... European journal of immunology 46 (3), 513-522, 2016 | 143 | 2016 |
Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb B Weigelin, E Bolaños, A Teijeira, I Martinez-Forero, S Labiano, ... Proceedings of the National Academy of Sciences 112 (24), 7551-7556, 2015 | 114 | 2015 |
Intratumor adoptive transfer of IL-12 mRNA transiently engineered antitumor CD8+ T cells I Etxeberria, E Bolaños, JI Quetglas, A Gros, A Villanueva, J Palomero, ... Cancer Cell 36 (6), 613-629. e7, 2019 | 109 | 2019 |
Virotherapy with a semliki forest virus–based vector encoding IL12 synergizes with PD-1/PD-L1 blockade JI Quetglas, S Labiano, MA Aznar, E Bolanos, A Azpilikueta, I Rodriguez, ... Cancer immunology research 3 (5), 449-454, 2015 | 102 | 2015 |
Cellular cytotoxicity is a form of immunogenic cell death L Minute, A Teijeira, AR Sanchez-Paulete, MC Ochoa, M Alvarez, I Otano, ... Journal for immunotherapy of cancer 8 (1), 2020 | 74 | 2020 |
Mitochondrial morphological and functional reprogramming following CD137 (4-1BB) costimulation A Teijeira, S Labiano, S Garasa, I Etxeberria, E Santamaría, A Rouzaut, ... Cancer immunology research 6 (7), 798-811, 2018 | 71 | 2018 |
Intratumoral immunotherapy with XCL1 and sFlt3L encoded in recombinant semliki forest virus–derived vectors fosters dendritic cell–mediated T-cell cross-priming AR Sánchez-Paulete, Á Teijeira, JI Quetglas, ME Rodríguez-Ruiz, ... Cancer Research 78 (23), 6643-6654, 2018 | 70 | 2018 |
Hypoxia-induced soluble CD137 in malignant cells blocks CD137L-costimulation as an immune escape mechanism S Labiano, A Palazón, E Bolanos, A Azpilikueta, AR Sánchez-Paulete, ... Oncoimmunology 5 (1), e1062967, 2016 | 56 | 2016 |
Successful immunotherapy against a transplantable mouse squamous lung carcinoma with anti–PD-1 and anti-CD137 monoclonal antibodies A Azpilikueta, J Agorreta, S Labiano, JL Pérez-Gracia, ... Journal of Thoracic Oncology 11 (4), 524-536, 2016 | 50 | 2016 |
CD137 (4-1BB) Costimulation Modifies DNA Methylation in CD8+ T Cell–Relevant Genes MA Aznar, S Labiano, A Diaz-Lagares, C Molina, S Garasa, A Azpilikueta, ... Cancer immunology research 6 (1), 69-78, 2018 | 42 | 2018 |
Brachytherapy attains abscopal effects when combined with immunostimulatory monoclonal antibodies ME Rodriguez-Ruiz, I Rodriguez, B Barbes, L Mayorga, ... Brachytherapy 16 (6), 1246-1251, 2017 | 42 | 2017 |
CD69 is a direct HIF-1α target gene in hypoxia as a mechanism enhancing expression on tumor-infiltrating T lymphocytes S Labiano, F Meléndez-Rodríguez, A Palazón, Á Teijeira, S Garasa, ... Oncoimmunology 6 (4), e1283468, 2017 | 39 | 2017 |
TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer MD Park, I Reyes-Torres, J LeBerichel, P Hamon, NM LaMarche, ... Nature immunology 24 (5), 792-801, 2023 | 33 | 2023 |