Sriram Chandrasekaran
Sriram Chandrasekaran
Assistant Professor of Biomedical Engineering at University of Michigan, Ann Arbor
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Probabilistic integrative modeling of genome-scale metabolic and regulatory networks in Escherichia coli and Mycobacterium tuberculosis
S Chandrasekaran, ND Price
Proceedings of the National Academy of Sciences 107 (41), 17845-17850, 2010
LIN28 regulates stem cell metabolism and conversion to primed pluripotency
J Zhang, S Ratanasirintrawoot, S Chandrasekaran, Z Wu, SB Ficarro, ...
Cell stem cell 19 (1), 66-80, 2016
Behavior-specific changes in transcriptional modules lead to distinct and predictable neurogenomic states
S Chandrasekaran, SA Ament, JA Eddy, SL Rodriguez-Zas, BR Schatz, ...
Proceedings of the National Academy of Sciences 108 (44), 18020-18025, 2011
Molecular signatures from omics data: from chaos to consensus
J Sung, Y Wang, S Chandrasekaran, DM Witten, ND Price
Biotechnology journal 7 (8), 946-957, 2012
Chemogenomics and orthology‐based design of antibiotic combination therapies
S Chandrasekaran, M Cokol‐Cakmak, N Sahin, K Yilancioglu, H Kazan, ...
Molecular systems biology 12 (5), 872, 2016
A system‐level model for the microbial regulatory genome
AN Brooks, DJ Reiss, A Allard, WJ Wu, DM Salvanha, CL Plaisier, ...
Molecular systems biology 10 (7), 740, 2014
Aggression is associated with aerobic glycolysis in the honey bee brain
S Chandrasekaran, CC Rittschof, D Djukovic, H Gu, D Raftery, ND Price, ...
Genes, Brain and Behavior 14 (2), 158-166, 2015
Granzyme B disrupts central metabolism and protein synthesis in bacteria to promote an immune cell death program
F Dotiwala, SS Santara, AA Binker-Cosen, B Li, S Chandrasekaran*, ...
Cell 171 (5), 1125-1137. e11, 2017
Temporal dynamics of neurogenomic plasticity in response to social interactions in male threespined sticklebacks
SA Bukhari, MC Saul, CH Seward, H Zhang, M Bensky, N James, ...
PLoS genetics 13 (7), e1006840, 2017
Behavioral, transcriptomic and epigenetic responses to social challenge in honey bees
HY Shpigler, MC Saul, EE Murdoch, AC Cash‐Ahmed, CH Seward, ...
Genes, Brain and Behavior 16 (6), 579-591, 2017
Comprehensive mapping of pluripotent stem cell metabolism using dynamic genome-scale network modeling
S Chandrasekaran, J Zhang, Z Sun, L Zhang, CA Ross, YC Huang, ...
Cell reports 21 (10), 2965-2977, 2017
Transcriptional regulatory dynamics drive coordinated metabolic and neural response to social challenge in mice
MC Saul, CH Seward, JM Troy, H Zhang, LG Sloofman, X Lu, PA Weisner, ...
Genome research 27 (6), 959-972, 2017
Metabolic constraint-based refinement of transcriptional regulatory networks
S Chandrasekaran, ND Price
PLoS computational biology 9 (12), e1003370, 2013
Cross‐species systems analysis of evolutionary toolkits of neurogenomic response to social challenge
MC Saul, C Blatti, W Yang, SA Bukhari, HY Shpigler, JM Troy, CH Seward, ...
Genes, Brain and Behavior 18 (1), e12502, 2019
Purine metabolism regulates DNA repair and therapy resistance in glioblastoma
W Zhou, Y Yao, AJ Scott, K Wilder-Romans, JJ Dresser, CK Werner, ...
Nature communications 11 (1), 1-14, 2020
Genome-scale network model of metabolism and histone acetylation reveals metabolic dependencies of histone deacetylase inhibitors
F Shen, L Boccuto, R Pauly, S Srikanth, S Chandrasekaran
Genome biology 20 (1), 1-15, 2019
Honey bee neurogenomic responses to affiliative and agonistic social interactions
HY Shpigler, MC Saul, EE Murdoch, F Corona, AC Cash‐Ahmed, ...
Genes, Brain and Behavior 18 (1), e12509, 2019
A guide to integrating transcriptional regulatory and metabolic networks using PROM (probabilistic regulation of metabolism)
E Simeonidis, S Chandrasekaran, ND Price
Systems Metabolic Engineering, 103-112, 2013
Systems biology of embryogenesis
LB Edelman, S Chandrasekaran, ND Price
Reproduction, Fertility and Development 22 (1), 98-105, 2009
Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy
BS Nelson, L Lin, DM Kremer, CM Sousa, C Cotta-Ramusino, A Myers, ...
Cancer & metabolism 8 (1), 1-16, 2020
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