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Tongde Wu
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A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62
A Lau, XJ Wang, F Zhao, NF Villeneuve, T Wu, T Jiang, Z Sun, E White, ...
Molecular and cellular biology 30 (13), 3275-3285, 2010
8582010
Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism
D Ren, NF Villeneuve, T Jiang, T Wu, A Lau, HA Toppin, DD Zhang
Proceedings of the National Academy of Sciences 108 (4), 1433-1438, 2011
6632011
Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis
T Wu, F Zhao, B Gao, C Tan, N Yagishita, T Nakajima, PK Wong, ...
Genes & development 28 (7), 708-722, 2014
3272014
PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function
J Ma, H Cai, T Wu, B Sobhian, Y Huo, A Alcivar, M Mehta, KL Cheung, ...
Molecular and cellular biology 32 (8), 1506-1517, 2012
2172012
Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention
DDZ Bryan Harder, Tao Jiang, Tongde Wu, Shasha Tao, Montserrat Rojo de la ...
Biochemical Society Transactions 43 (4), 680-686, 2015
1752015
KPNA6 (Importin α7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response
Z Sun, T Wu, F Zhao, A Lau, CM Birch, DD Zhang
Molecular and cellular biology 31 (9), 1800-1811, 2011
1282011
Nrf2 promotes neuronal cell differentiation
F Zhao, T Wu, A Lau, T Jiang, Z Huang, XJ Wang, W Chen, PK Wong, ...
Free Radical Biology and Medicine 47 (6), 867-879, 2009
1222009
USP15 negatively regulates Nrf2 through deubiquitination of Keap1
NF Villeneuve, W Tian, T Wu, Z Sun, A Lau, E Chapman, D Fang, ...
Molecular cell 51 (1), 68-79, 2013
1132013
Oxidative stress, mammospheres and Nrf2–new implication for breast cancer therapy?
T Wu, BG Harder, PK Wong, JE Lang, DD Zhang
Molecular carcinogenesis 54 (11), 1494-1502, 2015
1092015
p97 negatively regulates NRF2 by extracting ubiquitylated NRF2 from the KEAP1-CUL3 E3 complex
S Tao, P Liu, G Luo, M Rojo de la Vega, H Chen, T Wu, J Tillotson, ...
Molecular and cellular biology 37 (8), e00660-16, 2017
942017
Poly (ADP-ribose) polymerase-1 modulates Nrf2-dependent transcription
T Wu, XJ Wang, W Tian, MC Jaramillo, A Lau, DD Zhang
Free Radical Biology and Medicine 67, 69-80, 2014
522014
Identification of BPIFA1/SPLUNC1 as an epithelium-derived smooth muscle relaxing factor
T Wu, J Huang, PJ Moore, MS Little, WG Walton, RC Fellner, NE Alexis, ...
Nature communications 8 (1), 14118, 2017
502017
Interleukin-8 (IL-8) over-production and autocrine cell activation are key factors in monomethylarsonous acid [MMA (III)]-induced malignant transformation of urothelial cells
C Escudero-Lourdes, T Wu, JM Camarillo, AJ Gandolfi
Toxicology and applied pharmacology, 2011
442011
Withaferin A analogs that target the AAA+ chaperone p97
S Tao, J Tillotson, EMK Wijeratne, Y Xu, MJ Kang, T Wu, EC Lau, C Mesa, ...
ACS chemical biology 10 (8), 1916-1924, 2015
432015
SPLUNC1 is an allosteric modulator of the epithelial sodium channel
CS Kim, S Ahmad, T Wu, WG Walton, MR Redinbo, R Tarran
The FASEB Journal 32 (5), 2478, 2018
392018
Functional chromatography reveals three natural products that target the same protein with distinct mechanisms of action
MJ Kang, T Wu, EMK Wijeratne, EC Lau, DJ Mason, C Mesa, J Tillotson, ...
ChemBioChem 15 (14), 2125-2131, 2014
312014
Identification of a functional antioxidant response element within the eighth intron of the human ABCC3 gene
MJ Canet, MD Merrell, BG Harder, JM Maher, T Wu, AJ Lickteig, ...
Drug Metabolism and Disposition 43 (1), 93-99, 2015
242015
A SPLUNC1 peptidomimetic inhibits Orai1 and reduces inflammation in a murine allergic asthma model
JA Wrennall, S Ahmad, EN Worthington, T Wu, AS Goriounova, ...
American Journal of Respiratory Cell and Molecular Biology 66 (3), 271-282, 2022
162022
JUUL e-liquid exposure elicits cytoplasmic Ca2+ responses and leads to cytotoxicity in cultured airway epithelial cells
R Zhang, MM Jones, RE Dornsife, T Wu, V Sivaraman, R Tarran, ...
Toxicology letters 337, 46-56, 2021
132021
Involvement of PU. 1 in mouse adar-1 gene transcription induced by high-dose esiRNA
T Wu, Y Zhao, Z Hao, H Zhao, W Wang
International journal of biological macromolecules 45 (2), 157-162, 2009
72009
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