Mitochondria: the calcium connection L Contreras, I Drago, E Zampese, T Pozzan Biochimica et Biophysica Acta (BBA)-Bioenergetics 1797 (6-7), 607-618, 2010 | 449 | 2010 |
Whole-Exome Sequencing Identifies MDH2 as a New Familial Paraganglioma Gene A Cascón, I Comino-Méndez, M Currás-Freixes, AA de Cubas, ... Journal of the National Cancer Institute 107 (5), djv053, 2015 | 240 | 2015 |
Reduced N-acetylaspartate levels in mice lacking aralar, a brain-and muscle-type mitochondrial aspartate-glutamate carrier MA Jalil, L Begum, L Contreras, B Pardo, M Iijima, MX Li, M Ramos, ... Journal of Biological Chemistry 280 (35), 31333-31339, 2005 | 164 | 2005 |
Pyruvate kinase and aspartate-glutamate carrier distributions reveal key metabolic links between neurons and glia in retina KJ Lindsay, J Du, SR Sloat, L Contreras, JD Linton, SJ Turner, M Sadilek, ... Proceedings of the National Academy of Sciences 111 (43), 15579-15584, 2014 | 125 | 2014 |
Essential role of aralar in the transduction of small Ca+ signals to neuronal mitochondria B Pardo, L Contreras, A Serrano, M Ramos, K Kobayashi, M Iijima, ... Journal of Biological Chemistry 281 (2), 1039-1047, 2006 | 125 | 2006 |
Ca2+ Activation kinetics of the two aspartate-glutamate mitochondrial carriers, aralar and citrin: role in the heart malate-aspartate NADH shuttle L Contreras, P Gomez-Puertas, M Iijima, K Kobayashi, T Saheki, ... Journal of biological chemistry 282 (10), 7098-7106, 2007 | 113 | 2007 |
Brain glutamine synthesis requires neuronal-born aspartate as amino donor for glial glutamate formation B Pardo, TB Rodrigues, L Contreras, M Garzón, I Llorente-Folch, ... Journal of Cerebral Blood Flow & Metabolism 31 (1), 90-101, 2011 | 112 | 2011 |
Glutamate excitotoxicity and Ca2+-regulation of respiration: Role of the Ca2+ activated mitochondrial transporters (CaMCs) CB Rueda, I Llorente-Folch, J Traba, I Amigo, P Gonzalez-Sanchez, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1857 (8), 1158-1166, 2016 | 111 | 2016 |
Ca2+ dysregulation in neurons from transgenic mice expressing mutant presenilin 2 MJ Kipanyula, L Contreras, E Zampese, C Lazzari, AKC Wong, P Pizzo, ... Aging cell 11 (5), 885-893, 2012 | 109 | 2012 |
Calcium signaling in brain mitochondria L Contreras, J Satrústegui Journal of Biological Chemistry 284 (11), 7091-7099, 2009 | 109 | 2009 |
Phototransduction influences metabolic flux and nucleotide metabolism in mouse retina J Du, A Rountree, WM Cleghorn, L Contreras, KJ Lindsay, M Sadilek, ... Journal of Biological Chemistry 291 (9), 4698-4710, 2016 | 94 | 2016 |
Targeted exome sequencing of Krebs cycle genes reveals candidate cancer–predisposing mutations in pheochromocytomas and paragangliomas L Remacha, I Comino-Méndez, S Richter, L Contreras, M Currás-Freixes, ... Clinical Cancer Research 23 (20), 6315-6324, 2017 | 88 | 2017 |
Inhibition of mitochondrial pyruvate transport by zaprinast causes massive accumulation of aspartate at the expense of glutamate in the retina J Du, WM Cleghorn, L Contreras, K Lindsay, AM Rountree, AO Chertov, ... Journal of Biological Chemistry 288 (50), 36129-36140, 2013 | 87 | 2013 |
Ca2+ regulation of mitochondrial function in neurons CB Rueda, I Llorente-Folch, I Amigo, L Contreras, P González-Sánchez, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1837 (10), 1617-1624, 2014 | 65 | 2014 |
Role of aralar, the mitochondrial transporter of aspartate‐glutamate, in brain N‐acetylaspartate formation and Ca2+ signaling in neuronal mitochondria J Satrústegui, L Contreras, M Ramos, P Marmol, A Del Arco, T Saheki, ... Journal of neuroscience research 85 (15), 3359-3366, 2007 | 65 | 2007 |
Cytosolic reducing power preserves glutamate in retina J Du, W Cleghorn, L Contreras, JD Linton, GCK Chan, AO Chertov, ... Proceedings of the National Academy of Sciences 110 (46), 18501-18506, 2013 | 62 | 2013 |
Role of MDH2 pathogenic variant in pheochromocytoma and paraganglioma patients B Calsina, M Currás-Freixes, A Buffet, T Pons, L Contreras, R Letón, ... Genetics in Medicine 20 (12), 1652-1662, 2018 | 58 | 2018 |
De novo mutations in SLC25A24 cause a disorder characterized by early aging, bone dysplasia, characteristic face, and early demise K Writzl, A Maver, L Kovačič, P Martinez-Valero, L Contreras, ... The American Journal of Human Genetics 101 (5), 844-855, 2017 | 57 | 2017 |
Calcium regulation of mitochondrial carriers A Del Arco, L Contreras, B Pardo, J Satrustegui Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (10), 2413-2421, 2016 | 45 | 2016 |
De novo synthesis of glial glutamate and glutamine in young mice requires aspartate provided by the neuronal mitochondrial aspartate-glutamate carrier aralar/AGC1 B Pardo, L Contreras, J Satrústegui Frontiers in endocrinology 4, 70675, 2013 | 44 | 2013 |