|Structure-activity relationship of mutagenic aromatic and heteroaromatic nitro compounds. correlation with molecular orbital energies and hydrophobicity|
AK Debnath, RL Lopez de Compadre, G Debnath, AJ Shusterman, ...
Journal of medicinal chemistry 34 (2), 786-797, 1991
|Interaction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: implications for virus fusogenic mechanism and identification of fusion …|
S Liu, G Xiao, Y Chen, Y He, J Niu, CR Escalante, H Xiong, J Farmar, ...
The Lancet 363 (9413), 938-947, 2004
|Comparative quantitative structure− activity relationship studies on anti-HIV drugs|
R Garg, SP Gupta, H Gao, MS Babu, AK Debnath, C Hansch
Chemical reviews 99 (12), 3525-3602, 1999
|N-substituted pyrrole derivatives as novel human immunodeficiency virus type 1 entry inhibitors that interfere with the gp41 six-helix bundle formation and block virus fusion|
S Jiang, H Lu, S Liu, Q Zhao, Y He, AK Debnath
Antimicrobial agents and chemotherapy 48 (11), 4349-4359, 2004
|Structure-based identification of small molecule antiviral compounds targeted to the gp41 core structure of the human immunodeficiency virus type 1|
AK Debnath, L Radigan, S Jiang
Journal of medicinal chemistry 42 (17), 3203-3209, 1999
|Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops|
Y Do Kwon, A Finzi, X Wu, C Dogo-Isonagie, LK Lee, LR Moore, ...
Proceedings of the National Academy of Sciences 109 (15), 5663-5668, 2012
|Design of a Protein Surface Antagonist Based on α‐Helix Mimicry: Inhibition of gp41 Assembly and Viral Fusion|
JT Ernst, O Kutzki, AK Debnath, S Jiang, H Lu, AD Hamilton
Angewandte Chemie International Edition 41 (2), 278-281, 2002
|Identification of N-phenyl-N′-(2, 2, 6, 6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4|
Q Zhao, L Ma, S Jiang, H Lu, S Liu, Y He, N Strick, N Neamati, ...
Virology 339 (2), 213-225, 2005
|A cell-penetrating helical peptide as a potential HIV-1 inhibitor|
H Zhang, Q Zhao, S Bhattacharya, AA Waheed, X Tong, A Hong, S Heck, ...
Journal of molecular biology 378 (3), 565-580, 2008
|Theaflavin derivatives in black tea and catechin derivatives in green tea inhibit HIV-1 entry by targeting gp41|
S Liu, H Lu, Q Zhao, Y He, J Niu, AK Debnath, S Wu, S Jiang
Biochimica et Biophysica Acta (BBA)-General Subjects 1723 (1-3), 270-281, 2005
|Identification of a receptor-binding domain in the S protein of the novel human coronavirus Middle East respiratory syndrome coronavirus as an essential target for vaccine …|
L Du, G Zhao, Z Kou, C Ma, S Sun, VKM Poon, L Lu, L Wang, AK Debnath, ...
Journal of virology 87 (17), 9939-9942, 2013
|A QSAR investigation of the role of hydrophobicity in regulating mutagenicity in the Ames test: 1. Mutagenicity of aromatic and heteroaromatic amines in Salmonella typhimurium …|
AK Debnath, G Debnath, AJ Shusterman, C Hansch
Environmental and molecular mutagenesis 19 (1), 37-52, 1992
|Peptide and non-peptide HIV fusion inhibitors|
S Jing, Q Zhao, AK Debnath
Current pharmaceutical design 8 (8), 563-580, 2002
|Pharmacophore mapping of a series of 2, 4-diamino-5-deazapteridine inhibitors of Mycobacterium avium complex dihydrofolate reductase|
Journal of medicinal chemistry 45 (1), 41-53, 2002
|A screening assay for antiviral compounds targeted to the HIV-1 gp41 core structure using a conformation-specific monoclonal antibody|
S Jiang, K Lin, L Zhang, AK Debnath
Journal of virological methods 80 (1), 85-96, 1999
|Punica granatum (Pomegranate) juice provides an HIV-1 entry inhibitor and candidate topical microbicide|
AR Neurath, N Strick, YY Li, AK Debnath
BMC infectious diseases 4 (1), 1-12, 2004
|Design, synthesis, and structure− activity relationship of a novel series of 2-aryl 5-(4-oxo-3-phenethyl-2-thioxothiazolidinylidenemethyl) furans as HIV-1 entry inhibitors|
AR Katritzky, SR Tala, H Lu, AV Vakulenko, QY Chen, J Sivapackiam, ...
Journal of medicinal chemistry 52 (23), 7631-7639, 2009
|Cellulose acetate phthalate, a common pharmaceutical excipient, inactivates HIV-1 and blocks the coreceptor binding site on the virus envelope glycoprotein gp120|
AR Neurath, N Strick, YY Li, AK Debnath
BMC infectious diseases 1 (1), 1-12, 2001
|Three-dimensional quantitative structure− activity relationship study on cyclic urea derivatives as HIV-1 protease inhibitors: Application of comparative molecular field analysis|
Journal of Medicinal Chemistry 42 (2), 249-259, 1999
|Solution structure of a hydrocarbon stapled peptide inhibitor in complex with monomeric C-terminal domain of HIV-1 capsid|
S Bhattacharya, H Zhang, AK Debnath, D Cowburn
Journal of Biological Chemistry 283 (24), 16274-16278, 2008