| The structural basis of cyclic diguanylate signal transduction by PilZ domains J Benach, SS Swaminathan, R Tamayo, SK Handelman, ... The EMBO journal 26 (24), 5153-5166, 2007 | 284 | 2007 |
| Life-course genome-wide association study meta-analysis of total body BMD and assessment of age-specific effects C Medina-Gomez, JP Kemp, K Trajanoska, J Luan, A Chesi, TS Ahluwalia, ... The American Journal of Human Genetics 102 (1), 88-102, 2018 | 279 | 2018 |
| 17‐beta hydroxysteroid dehydrogenase 13 is a hepatic retinol dehydrogenase associated with histological features of nonalcoholic fatty liver disease Y Ma, OV Belyaeva, PM Brown, K Fujita, K Valles, S Karki, YS de Boer, ... Hepatology 69 (4), 1504-1519, 2019 | 209 | 2019 |
| Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19 C Mirabelli, JW Wotring, CJ Zhang, SM McCarty, R Fursmidt, CD Pretto, ... Proceedings of the National Academy of Sciences 118 (36), e2105815118, 2021 | 193 | 2021 |
| Understanding the physical properties that control protein crystallization by analysis of large-scale experimental data WN Price Ii, Y Chen, SK Handelman, H Neely, P Manor, R Karlin, R Nair, ... Nature biotechnology 27 (1), 51-57, 2009 | 189 | 2009 |
| Identification of eukaryotic and prokaryotic methylthiotransferase for biosynthesis of 2-methylthio-N6-threonylcarbamoyladenosine in tRNA S Arragain, SK Handelman, F Forouhar, FY Wei, K Tomizawa, JF Hunt, ... Journal of Biological Chemistry 285 (37), 28425-28433, 2010 | 155 | 2010 |
| The pharmacogenomics research network translational pharmacogenetics program: outcomes and metrics of pharmacogenetic implementations across diverse healthcare systems JA Luzum, RE Pakyz, AR Elsey, CE Haidar, JF Peterson, M Whirl‐Carrillo, ... Clinical Pharmacology & Therapeutics 102 (3), 502-510, 2017 | 128 | 2017 |
| Physiological response to membrane protein overexpression in E. coli F Gubellini, G Verdon, NK Karpowich, JD Luff, G Boel, N Gauthier, ... Molecular & Cellular Proteomics 10 (10), 2011 | 118 | 2011 |
| Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease LH Maguire, SK Handelman, X Du, Y Chen, TH Pers, EK Speliotes Nature genetics 50 (10), 1359-1365, 2018 | 112 | 2018 |
| Missing heritability of common diseases and treatments outside the protein-coding exome W Sadee, K Hartmann, M Seweryn, M Pietrzak, SK Handelman, ... Human genetics 133, 1199-1215, 2014 | 84 | 2014 |
| Crystal structures of Phd-Doc, HigA, and YeeU establish multiple evolutionary links between microbial growth-regulating toxin-antitoxin systems MA Arbing, SK Handelman, AP Kuzin, G Verdon, C Wang, M Su, ... Structure 18 (8), 996-1010, 2010 | 81 | 2010 |
| Relative reactivity of lysine and other peptide-bound amino acids to oxidation by hypochlorite ZD Nightingale, AH Lancha Jr, SK Handelman, GG Dolnikowski, ... Free Radical Biology and Medicine 29 (5), 425-433, 2000 | 77 | 2000 |
| Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology VL Chen, X Du, Y Chen, A Kuppa, SK Handelman, RB Vohnoutka, ... Nature communications 12 (1), 816, 2021 | 76 | 2021 |
| Whole transcriptome RNA-Seq allelic expression in human brain RM Smith, A Webb, AC Papp, LC Newman, SK Handelman, A Suhy, ... BMC genomics 14, 1-15, 2013 | 59 | 2013 |
| Insulin resistance exacerbates genetic predisposition to nonalcoholic fatty liver disease in individuals without diabetes L Barata, MF Feitosa, LF Bielak, B Halligan, AS Baldridge, X Guo, ... Hepatology communications 3 (7), 894-907, 2019 | 50 | 2019 |
| AmpliSeq transcriptome analysis of human alveolar and monocyte-derived macrophages over time in response to Mycobacterium tuberculosis infection AC Papp, AK Azad, M Pietrzak, A Williams, SK Handelman, RP Igo Jr, ... PloS one 13 (5), e0198221, 2018 | 47 | 2018 |
| Structural genomics target selection for the New York consortium on membrane protein structure M Punta, J Love, S Handelman, JF Hunt, L Shapiro, WA Hendrickson, ... Journal of structural and functional genomics 10, 255-268, 2009 | 47 | 2009 |
| BET bromodomain inhibition blocks an AR-repressed, E2F1-activated treatment-emergent neuroendocrine prostate cancer lineage plasticity program DH Kim, D Sun, WK Storck, K Welker Leng, C Jenkins, DJ Coleman, ... Clinical Cancer Research 27 (17), 4923-4936, 2021 | 43 | 2021 |
| Genetic variants that associate with cirrhosis have pleiotropic effects on human traits VL Chen, Y Chen, X Du, SK Handelman, EK Speliotes Liver International 40 (2), 405-415, 2020 | 42 | 2020 |
| RNA sequencing of transcriptomes in human brain regions: protein-coding and non-coding RNAs, isoforms and alleles A Webb, AC Papp, A Curtis, LC Newman, M Pietrzak, M Seweryn, ... BMC genomics 16, 1-16, 2015 | 41 | 2015 |
