Kisspeptin signaling is indispensable for neurokinin B, but not glutamate, stimulation of gonadotropin secretion in mice D García-Galiano, D van Ingen Schenau, S Leon, MAM Krajnc-Franken, ... Endocrinology 153 (1), 316-328, 2012 | 193 | 2012 |
Role of neurokinin B in the control of female puberty and its modulation by metabolic status VM Navarro, F Ruiz-Pino, MA Sánchez-Garrido, D García-Galiano, ... Journal of Neuroscience 32 (7), 2388-2397, 2012 | 172 | 2012 |
Defining a novel leptin–melanocortin–kisspeptin pathway involved in the metabolic control of puberty M Manfredi-Lozano, J Roa, F Ruiz-Pino, R Piet, D Garcia-Galiano, ... Molecular metabolism 5 (10), 844-857, 2016 | 162 | 2016 |
Connecting metabolism and gonadal function: novel central neuropeptide pathways involved in the metabolic control of puberty and fertility M Manfredi-Lozano, J Roa, M Tena-Sempere Frontiers in neuroendocrinology 48, 37-49, 2018 | 150 | 2018 |
Changes in Hypothalamic Expression of the Lin28/let-7 System and Related MicroRNAs During Postnatal Maturation and After Experimental Manipulations of … S Sangiao-Alvarellos, M Manfredi-Lozano, F Ruiz-Pino, VM Navarro, ... Endocrinology 154 (2), 942-955, 2013 | 147 | 2013 |
Kisspeptin receptor haplo-insufficiency causes premature ovarian failure despite preserved gonadotropin secretion F Gaytan, D Garcia-Galiano, MD Dorfman, M Manfredi-Lozano, ... Endocrinology 155 (8), 3088-3097, 2014 | 118 | 2014 |
Physiological roles of gonadotropin-inhibitory hormone signaling in the control of mammalian reproductive axis: studies in the NPFF1 receptor null mouse S León, D García-Galiano, F Ruiz-Pino, A Barroso, M Manfredi-Lozano, ... Endocrinology 155 (8), 2953-2965, 2014 | 114 | 2014 |
Metabolic programming of puberty: sexually dimorphic responses to early nutritional challenges MA Sanchez-Garrido, JM Castellano, F Ruiz-Pino, D Garcia-Galiano, ... Endocrinology 154 (9), 3387-3400, 2013 | 104 | 2013 |
Direct actions of kisspeptins on GnRH neurons permit attainment of fertility but are insufficient to fully preserve gonadotropic axis activity S León, A Barroso, MJ Vázquez, D García-Galiano, M Manfredi-Lozano, ... Scientific reports 6 (1), 19206, 2016 | 85 | 2016 |
Perturbation of hypothalamic microRNA expression patterns in male rats after metabolic distress: impact of obesity and conditions of negative energy balance S Sangiao-Alvarellos, L Pena-Bello, M Manfredi-Lozano, ... Endocrinology 155 (5), 1838-1850, 2014 | 85 | 2014 |
Obesity-induced hypogonadism in the male: premature reproductive neuroendocrine senescence and contribution of Kiss1-mediated mechanisms MA Sánchez-Garrido, F Ruiz-Pino, M Manfredi-Lozano, S Leon, ... Endocrinology 155 (3), 1067-1079, 2014 | 78 | 2014 |
Metabolic regulation of female puberty via hypothalamic AMPK–kisspeptin signaling J Roa, A Barroso, F Ruiz-Pino, MJ Vázquez, P Seoane-Collazo, ... Proceedings of the National Academy of Sciences 115 (45), E10758-E10767, 2018 | 71 | 2018 |
Distinct expression patterns predict differential roles of the miRNA-binding proteins, Lin28 and Lin28b, in the mouse testis: studies during postnatal development and in a … F Gaytan, S Sangiao-Alvarellos, M Manfredi-Lozano, D García-Galiano, ... Endocrinology 154 (3), 1321-1336, 2013 | 62 | 2013 |
Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3 V Heras, S Sangiao-Alvarellos, M Manfredi-Lozano, MJ Sanchez-Tapia, ... PLoS biology 17 (11), e3000532, 2019 | 60 | 2019 |
Effects and interactions of tachykinins and dynorphin on FSH and LH secretion in developing and adult rats F Ruiz-Pino, D Garcia-Galiano, M Manfredi-Lozano, S Leon, ... Endocrinology 156 (2), 576-588, 2015 | 55 | 2015 |
Kisspeptin treatment induces gonadotropic responses and rescues ovulation in a subset of preclinical models and women with polycystic ovary syndrome A Romero-Ruiz, K Skorupskaite, F Gaytan, E Torres, C Perdices-Lopez, ... Human Reproduction 34 (12), 2495-2512, 2019 | 49 | 2019 |
GnRH replacement rescues cognition in Down syndrome M Manfredi-Lozano, V Leysen, M Adamo, I Paiva, R Rovera, JM Pignat, ... Science 377 (6610), eabq4515, 2022 | 47 | 2022 |
Intergenerational influence of paternal obesity on metabolic and reproductive health parameters of the offspring: male-preferential impact and involvement of Kiss1-mediated … MA Sanchez-Garrido, F Ruiz-Pino, I Velasco, A Barroso, D Fernandois, ... Endocrinology 159 (2), 1005-1018, 2018 | 46 | 2018 |
Metabolic and gonadotropic impact of sequential obesogenic insults in the female: influence of the loss of ovarian secretion MA Sanchez-Garrido, F Ruiz-Pino, M Manfredi-Lozano, S Leon, V Heras, ... Endocrinology 156 (8), 2984-2998, 2015 | 37 | 2015 |
GnRH neurons recruit astrocytes in infancy to facilitate network integration and sexual maturation G Pellegrino, M Martin, C Allet, T Lhomme, S Geller, D Franssen, ... Nature neuroscience 24 (12), 1660-1672, 2021 | 33 | 2021 |