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María Manfredi-Lozano
María Manfredi-Lozano
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Kisspeptin signaling is indispensable for neurokinin B, but not glutamate, stimulation of gonadotropin secretion in mice
D García-Galiano, D van Ingen Schenau, S Leon, MAM Krajnc-Franken, ...
Endocrinology 153 (1), 316-328, 2012
1912012
Role of neurokinin B in the control of female puberty and its modulation by metabolic status
VM Navarro, F Ruiz-Pino, MA Sánchez-Garrido, D García-Galiano, ...
Journal of Neuroscience 32 (7), 2388-2397, 2012
1712012
Defining a novel leptin–melanocortin–kisspeptin pathway involved in the metabolic control of puberty
M Manfredi-Lozano, J Roa, F Ruiz-Pino, R Piet, D Garcia-Galiano, ...
Molecular metabolism 5 (10), 844-857, 2016
1562016
Changes in Hypothalamic Expression of the Lin28/let-7 System and Related MicroRNAs During Postnatal Maturation and After Experimental Manipulations of …
S Sangiao-Alvarellos, M Manfredi-Lozano, F Ruiz-Pino, VM Navarro, ...
Endocrinology 154 (2), 942-955, 2013
1462013
Connecting metabolism and gonadal function: novel central neuropeptide pathways involved in the metabolic control of puberty and fertility
M Manfredi-Lozano, J Roa, M Tena-Sempere
Frontiers in neuroendocrinology 48, 37-49, 2018
1452018
Physiological roles of gonadotropin-inhibitory hormone signaling in the control of mammalian reproductive axis: studies in the NPFF1 receptor null mouse
S León, D García-Galiano, F Ruiz-Pino, A Barroso, M Manfredi-Lozano, ...
Endocrinology 155 (8), 2953-2965, 2014
1152014
Kisspeptin receptor haplo-insufficiency causes premature ovarian failure despite preserved gonadotropin secretion
F Gaytan, D Garcia-Galiano, MD Dorfman, M Manfredi-Lozano, ...
Endocrinology 155 (8), 3088-3097, 2014
1122014
Metabolic programming of puberty: sexually dimorphic responses to early nutritional challenges
MA Sanchez-Garrido, JM Castellano, F Ruiz-Pino, D Garcia-Galiano, ...
Endocrinology 154 (9), 3387-3400, 2013
1032013
Direct actions of kisspeptins on GnRH neurons permit attainment of fertility but are insufficient to fully preserve gonadotropic axis activity
S León, A Barroso, MJ Vázquez, D García-Galiano, M Manfredi-Lozano, ...
Scientific reports 6 (1), 19206, 2016
852016
Perturbation of hypothalamic microRNA expression patterns in male rats after metabolic distress: impact of obesity and conditions of negative energy balance
S Sangiao-Alvarellos, L Pena-Bello, M Manfredi-Lozano, ...
Endocrinology 155 (5), 1838-1850, 2014
792014
Obesity-induced hypogonadism in the male: premature reproductive neuroendocrine senescence and contribution of Kiss1-mediated mechanisms
MA Sánchez-Garrido, F Ruiz-Pino, M Manfredi-Lozano, S Leon, ...
Endocrinology 155 (3), 1067-1079, 2014
742014
Metabolic regulation of female puberty via hypothalamic AMPK–kisspeptin signaling
J Roa, A Barroso, F Ruiz-Pino, MJ Vázquez, P Seoane-Collazo, ...
Proceedings of the National Academy of Sciences 115 (45), E10758-E10767, 2018
692018
Distinct expression patterns predict differential roles of the miRNA-binding proteins, Lin28 and Lin28b, in the mouse testis: studies during postnatal development and in a …
F Gaytan, S Sangiao-Alvarellos, M Manfredi-Lozano, D García-Galiano, ...
Endocrinology 154 (3), 1321-1336, 2013
612013
Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3
V Heras, S Sangiao-Alvarellos, M Manfredi-Lozano, MJ Sanchez-Tapia, ...
PLoS biology 17 (11), e3000532, 2019
572019
Effects and interactions of tachykinins and dynorphin on FSH and LH secretion in developing and adult rats
F Ruiz-Pino, D Garcia-Galiano, M Manfredi-Lozano, S Leon, ...
Endocrinology 156 (2), 576-588, 2015
562015
Intergenerational influence of paternal obesity on metabolic and reproductive health parameters of the offspring: male-preferential impact and involvement of Kiss1-mediated …
MA Sanchez-Garrido, F Ruiz-Pino, I Velasco, A Barroso, D Fernandois, ...
Endocrinology 159 (2), 1005-1018, 2018
452018
Kisspeptin treatment induces gonadotropic responses and rescues ovulation in a subset of preclinical models and women with polycystic ovary syndrome
A Romero-Ruiz, K Skorupskaite, F Gaytan, E Torres, C Perdices-Lopez, ...
Human Reproduction 34 (12), 2495-2512, 2019
432019
Metabolic and gonadotropic impact of sequential obesogenic insults in the female: influence of the loss of ovarian secretion
MA Sanchez-Garrido, F Ruiz-Pino, M Manfredi-Lozano, S Leon, V Heras, ...
Endocrinology 156 (8), 2984-2998, 2015
392015
GnRH replacement rescues cognition in Down syndrome
M Manfredi-Lozano, V Leysen, M Adamo, I Paiva, R Rovera, JM Pignat, ...
Science 377 (6610), eabq4515, 2022
382022
Testicular expression of the Lin28/let-7 system: Hormonal regulation and changes during postnatal maturation and after manipulations of puberty
S Sangiao-Alvarellos, M Manfredi-Lozano, F Ruiz-Pino, S León, ...
Scientific Reports 5 (1), 15683, 2015
332015
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